Brain TSPO-PET predicts later disease progression independent of relapses in multiple sclerosis

Insights into disseminated MS brain pathology with multimodal diffusion tensor and PET imaging

(2020) Svetlana Bezukladova et al.   Neurology-Neuroimmunology & Neuroinflammation

Transcriptional profiling of human microglia reveals grey–white matter heterogeneity and multiple sclerosis-associated changes

(2019) Marlijn van der Poel et al.   Nature Communications

Silent Progression in Disease Activity-Free Relapsing Multiple Sclerosis

(2019) et al.   ANNALS OF NEUROLOGY

Plasma Neurofilaments correlate with Disability in Progressive Multiple Sclerosis patients

(2019) Diana Ferraro et al.   ACTA NEUROLOGICA SCANDINAVICA

Natalizumab treatment reduces microglial activation in the white matter of the MS brain

(2019) Marcus Sucksdorff et al.   Neurology-Neuroimmunology & Neuroinflammation

Association of Chronic Active Multiple Sclerosis Lesions With Disability In Vivo

(2019) Martina Absinta et al.   JAMA Neurology

Additive Effect of Spinal Cord Volume, Diffuse and Focal Cord Pathology on Disability in Multiple Sclerosis

(2019) Michaela Andelova et al.   Frontiers in Neurology

A quantitative neuropathological assessment of translocator protein expression in multiple sclerosis

(2019) Erik Nutma et al.   BRAIN

Serum neurofilament as a predictor of disease worsening and brain and spinal cord atrophy in multiple sclerosis

(2018) Christian Barro et al.   BRAIN

Diagnosis of multiple sclerosis: 2017 revisions of the McDonald criteria

(2018) Alan J Thompson et al.   LANCET NEUROLOGY

Spinal cord volume loss

(2018) Charidimos Tsagkas et al.   NEUROLOGY

Spinal Cord Atrophy in Multiple Sclerosis: A Systematic Review and Meta-Analysis

(2018) Courtney Casserly et al.   JOURNAL OF NEUROIMAGING

Positron emission tomography imaging in evaluation of MS pathology in vivo

(2018) Heidi Högel et al.   Multiple Sclerosis Journal

Neurofilaments and 10-year follow-up in multiple sclerosis

(2018) Alok Bhan et al.   Multiple Sclerosis Journal

TSPO in diverse CNS pathologies and psychiatric disease: A critical review and a way forward

(2018) Tomás R. Guilarte   PHARMACOLOGY & THERAPEUTICS

Atrophied brain lesion volume, a magnetic resonance imaging biomarker for monitoring neurodegenerative changes in multiple sclerosis

(2018) Robert Zivadinov et al.   QUANTITATIVE IMAGING IN MEDICINE AND SURGERY

Characterizing Clinical and MRI Dissociation in Patients with Multiple Sclerosis

(2017) Brian C. Healy et al.   JOURNAL OF NEUROIMAGING

PETPVE12: an SPM toolbox for Partial Volume Effects correction in brain PET – Application to amyloid imaging with AV45-PET

(2017) Gabriel Gonzalez-Escamilla et al.   NEUROIMAGE

Clinical relevance of brain atrophy assessment in multiple sclerosis. Implications for its use in a clinical routine

(2016) Robert Zivadinov et al.   Expert Review of Neurotherapeutics

Neurofilament in CSF—A biomarker of disease activity and long-term prognosis in multiple sclerosis

(2016) Per Soelberg Sorensen et al.   Multiple Sclerosis Journal

Clinical relevance of brain atrophy assessment in multiple sclerosis. Implications for its use in a clinical routine

(2016) Robert Zivadinov et al.   Expert Review of Neurotherapeutics

Neurofilament in CSF—A biomarker of disease activity and long-term prognosis in multiple sclerosis

(2016) Per Soelberg Sorensen et al.   Multiple Sclerosis Journal

Erratum: Multiple sclerosis—a quiet revolution

(2015) Richard M. Ransohoff et al.   Nature Reviews Neurology

MAGNIMS consensus guidelines on the use of MRI in multiple sclerosis—establishing disease prognosis and monitoring patients

(2015)   Nature Reviews Neurology

Association of Cortical Lesion Burden on 7-T Magnetic Resonance Imaging With Cognition and Disability in Multiple Sclerosis

(2015) Daniel M. Harrison et al.   JAMA Neurology

Increased PK11195-PET binding in normal-appearing white matter in clinically isolated syndrome

(2014) Paolo Giannetti et al.   BRAIN

Clinical Relevance of Brain Volume Measures in Multiple Sclerosis

(2014) Nicola De Stefano et al.   CNS DRUGS

Brain atrophy and disability progression in multiple sclerosis patients: a 10-year follow-up study

(2014) Cecilie Jacobsen et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

In Vivo Detection of Diffuse Inflammation in Secondary Progressive Multiple Sclerosis Using PET Imaging and the Radioligand 11C-PK11195

(2014) E. Rissanen et al.   JOURNAL OF NUCLEAR MEDICINE

The central role of mitochondria in axonal degeneration in multiple sclerosis

(2014) Graham R Campbell et al.   Multiple Sclerosis Journal

Microglia activation in multiple sclerosis black holes predicts outcome in progressive patients: An in vivo [(11)C](R)-PK11195-PET pilot study

(2014) Paolo Giannetti et al.   NEUROBIOLOGY OF DISEASE

Brain atrophy and lesion load predict long term disability in multiple sclerosis

(2013) Veronica Popescu et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Magnetic resonance imaging correlates of physical disability in relapse onset multiple sclerosis of long disease duration

(2013) H Kearney et al.   Multiple Sclerosis Journal

Relevance of Spinal Cord Abnormalities to Clinical Disability in Multiple Sclerosis: MR Imaging Findings in a Large Cohort of Patients

(2013) Carsten Lukas et al.   RADIOLOGY

NADPH oxidase expression in active multiple sclerosis lesions in relation to oxidative tissue damage and mitochondrial injury

(2012) Marie T. Fischer et al.   BRAIN

Optimization of Supervised Cluster Analysis for Extracting Reference Tissue Input Curves in (R)-[11C]PK11195 Brain PET Studies

(2012) Maqsood Yaqub et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Onset of progressive phase is an age-dependent clinical milestone in multiple sclerosis

(2012) M. Tutuncu et al.   Multiple Sclerosis Journal

Increased PK11195 PET binding in the cortex of patients with MS correlates with disability

(2012) M. Politis et al.   NEUROLOGY

An 18-kDa Translocator Protein (TSPO) Polymorphism Explains Differences in Binding Affinity of the PET Radioligand PBR28

(2011) David R Owen et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

An automated tool for detection of FLAIR-hyperintense white-matter lesions in Multiple Sclerosis

(2011) Paul Schmidt et al.   NEUROIMAGE

Age and disability accumulation in multiple sclerosis

(2011) A. Scalfari et al.   NEUROLOGY

Assessing brain atrophy rates in a large population of untreated multiple sclerosis subtypes

(2010) N. De Stefano et al.   NEUROLOGY

Role of the innate immune system in the pathogenesis of multiple sclerosis

(2009) Roopali Gandhi et al.   JOURNAL OF NEUROIMMUNOLOGY

Disability and T2 MRI lesions: a 20-year follow-up of patients with relapse onset of multiple sclerosis

(2008) L. K. Fisniku et al.   BRAIN

Multiple sclerosis

(2008) Alastair Compston et al.   LANCET

Magnetic resonance imaging metrics and their correlation with clinical outcomes in multiple sclerosis: a review of the literature and future perspectives

(2008) D Bar-Zohar et al.   Multiple Sclerosis Journal

Natural history of secondary-progressive multiple sclerosis

(2008) Helen Tremlett et al.   Multiple Sclerosis Journal