TheMycobacterium tuberculosisprotein pair PE9 (Rv1088)-PE10 (Rv1089) forms heterodimers and induces macrophage apoptosis through Toll-like receptor 4

Mycobacterium TuberculosisPPE Family Protein Rv1808 Manipulates Cytokines Profile via Co-Activation of MAPK and NF-κB Signaling Pathways

(2014) Wanyan Deng et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

An immunomodulatory role for theMycobacterium tuberculosisregion of difference 1 locus proteins PE35 (Rv3872) and PPE68 (Rv3873)

(2014) Bhavana Tiwari et al.   FEBS Journal

Type I IFNs Enhance Susceptibility to Chlamydia muridarum Lung Infection by Enhancing Apoptosis of Local Macrophages

(2014) H. Qiu et al.   JOURNAL OF IMMUNOLOGY

Type I IFN Induces IL-10 Production in an IL-27–Independent Manner and Blocks Responsiveness to IFN-γ for Production of IL-12 and Bacterial Killing inMycobacterium tuberculosis–Infected Macrophages

(2014) Finlay W. McNab et al.   JOURNAL OF IMMUNOLOGY

Structure of a PE-PPE-EspG complex from Mycobacterium tuberculosis reveals molecular specificity of ESX protein secretion

(2014) D. C. Ekiert et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bim is a crucial regulator of apoptosis induced by Mycobacterium tuberculosis

(2014) N Aguiló et al.   Cell Death & Disease

Receptor-mediated recognition of mycobacterial pathogens

(2013) Kate E. Killick et al.   CELLULAR MICROBIOLOGY

ESX-1-induced apoptosis is involved in cell-to-cell spread ofMycobacterium tuberculosis

(2013) J. I. Aguilo et al.   CELLULAR MICROBIOLOGY

Interferon-Regulatory Factors Determine Macrophage Phenotype Polarization

(2013) Roman Günthner et al.   MEDIATORS OF INFLAMMATION

The PPE Domain of PPE17 Is Responsible for Its Surface Localization and Can Be Used to Express Heterologous Proteins on the Mycobacterial Surface

(2013) Valentina Donà et al.   PLoS One

Pattern Recognition Receptors and Cytokines inMycobacterium tuberculosisInfection—The Double-Edged Sword?

(2013) Md. Murad Hossain et al.   Biomed Research International

ESX-1-induced apoptosis during mycobacterial infection: to be or not to be, that is the question

(2013) Nacho Aguiló et al.   Frontiers in Cellular and Infection Microbiology

Functional dissection of protein domains involved in the immunomodulatory properties of PE_PGRS33 ofMycobacterium tuberculosis

(2013) Antonella Zumbo et al.   Pathogens and Disease

The 19 kDaMycobacterium tuberculosisLipoprotein (LpqH) Induces Macrophage Apoptosis through Extrinsic and Intrinsic Pathways: A Role for the Mitochondrial Apoptosis-Inducing Factor

(2012) Alejandro Sánchez et al.   Clinical & Developmental Immunology

Proline-Proline-Glutamic Acid (PPE) Protein Rv1168c ofMycobacterium tuberculosisAugments Transcription from HIV-1 Long Terminal Repeat Promoter

(2012) Khalid Hussain Bhat et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Mycobacterium tuberculosis PE Proteins Rv0285 and Rv1386 Modulate Innate Immunity and Mediate Bacillary Survival in Macrophages

(2012) Bhavana Mishra Tiwari et al.   PLoS One

The PE/PPE multigene family codes for virulence factors and is a possible source of mycobacterial antigenic variation: Perhaps more?

(2011) Yusuf Akhter et al.   BIOCHIMIE

Innate Immune Recognition ofMycobacterium tuberculosis

(2011) Johanneke Kleinnijenhuis et al.   Clinical & Developmental Immunology

Mycobacterial PE/PPE Proteins at the Host-Pathogen Interface

(2011) Samantha L. Sampson   Clinical & Developmental Immunology

Mycobacterium tuberculosis Triggers Host Type I IFN Signaling To Regulate IL-1  Production in Human Macrophages

(2011) A. Novikov et al.   JOURNAL OF IMMUNOLOGY

The PE-PPE Domain in Mycobacterium Reveals a Serine α/β Hydrolase Fold and Function: An In-Silico Analysis

(2011) Rafiya Sultana et al.   PLoS One

Functional Dissection of the PE Domain Responsible for Translocation of PE_PGRS33 across the Mycobacterial Cell Wall

(2011) Alessandro Cascioferro et al.   PLoS One

The PE and PPE proteins of Mycobacterium tuberculosis

(2011) Sangita Mukhopadhyay et al.   TUBERCULOSIS

Src Homology 3-interacting Domain of Rv1917c ofMycobacterium tuberculosisInduces Selective Maturation of Human Dendritic Cells by Regulating PI3K-MAPK-NF-κB Signaling and Drives Th2 Immune Responses

(2010) Kushagra Bansal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Multifunctional PE_PGRS11 Protein fromMycobacterium tuberculosisPlays a Role in Regulating Resistance to Oxidative Stress

(2010) Rashmi Chaturvedi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Type I interferon: friend or foe?

(2010) Giorgio Trinchieri   JOURNAL OF EXPERIMENTAL MEDICINE

Cutting Edge: Caspase-1 Independent IL-1  Production Is Critical for Host Resistance to Mycobacterium tuberculosis and Does Not Require TLR Signaling In Vivo

(2010) K. D. Mayer-Barber et al.   JOURNAL OF IMMUNOLOGY

The Role of the Granuloma in Expansion and Dissemination of Early Tuberculous Infection

(2009) J. Muse Davis et al.   CELL

Role of TLR2- and TLR4-mediated signaling in Mycobacterium tuberculosis-induced macrophage death

(2009) Dulfary Sánchez et al.   CELLULAR IMMUNOLOGY

The PPE18 of Mycobacterium tuberculosis Interacts with TLR2 and Activates IL-10 Induction in Macrophage

(2009) S. Nair et al.   JOURNAL OF IMMUNOLOGY

Mycobacterium tuberculosis Prevents Inflammasome Activation

(2008) Sharon S. Master et al.   Cell Host & Microbe

ESX-1-dependent cytolysis in lysosome secretion and inflammasome activation during mycobacterial infection

(2008) Ingrid C. Koo et al.   CELLULAR MICROBIOLOGY

The Co-Operonic PE25/PPE41 Protein Complex of Mycobacterium tuberculosis Elicits Increased Humoral and Cell Mediated Immune Response

(2008) Smanla Tundup et al.   PLoS One

Mycobacterium tuberculosis38-kDa Lipoprotein is Apoptogenic for Human Monocyte-derived Macrophages

(2008) A. Sanchez et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Identifying Cognate Binding Pairs among a Large Set of Paralogs: The Case of PE/PPE Proteins of Mycobacterium tuberculosis

(2008) Robert Riley et al.   PLoS Computational Biology