Mycobacterial PE/PPE Proteins at the Host-Pathogen Interface

The candidate tuberculosis vaccine Mtb72F/AS02A: Tolerability and immunogenicity in humans

(2014) Kenneth Von Eschen et al.   Human vaccines & immunotherapeutics

The ESX-5 Secretion System of Mycobacterium marinum Modulates the Macrophage Response

(2014) A. M. Abdallah et al.   JOURNAL OF IMMUNOLOGY

Identification of Human T Cell Antigens for the Development of Vaccines against Mycobacterium tuberculosis

(2014) S. Bertholet et al.   JOURNAL OF IMMUNOLOGY

Using epitope predictions to evaluate efficacy and population coverage of the Mtb72f vaccine for tuberculosis

(2010) Lucy A McNamara et al.   BMC IMMUNOLOGY

Virulence-related Mycobacterium avium subsp hominissuis MAV_2928 gene is associated with vacuole remodeling in macrophages

(2010) Samradhni S Jha et al.   BMC MICROBIOLOGY

Definition of novel cell envelope associated proteins in Triton X-114 extracts of Mycobacterium tuberculosis H37Rv

(2010) Hiwa Målen et al.   BMC MICROBIOLOGY

Evaluation of the Safety and Immunogenicity of Two Antigen Concentrations of the Mtb72F/AS02A Candidate Tuberculosis Vaccine in Purified Protein Derivative-Negative Adults

(2010) I. Leroux-Roels et al.   Clinical and Vaccine Immunology

Identification of Mycobacterium tuberculosis Antigens of High Serodiagnostic Value

(2010) G. C. Ireton et al.   Clinical and Vaccine Immunology

A key role for lung-resident memory lymphocytes in protective immune responses after BCG vaccination

(2010) Lisa M. Connor et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Src Homology 3-interacting Domain of Rv1917c ofMycobacterium tuberculosisInduces Selective Maturation of Human Dendritic Cells by Regulating PI3K-MAPK-NF-κB Signaling and Drives Th2 Immune Responses

(2010) Kushagra Bansal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Multifunctional PE_PGRS11 Protein fromMycobacterium tuberculosisPlays a Role in Regulating Resistance to Oxidative Stress

(2010) Rashmi Chaturvedi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PE_PGRS Antigens of Mycobacterium tuberculosis Induce Maturation and Activation of Human Dendritic Cells

(2010) K. Bansal et al.   JOURNAL OF IMMUNOLOGY

Human T cell epitopes of Mycobacterium tuberculosis are evolutionarily hyperconserved

(2010) Iñaki Comas et al.   NATURE GENETICS

Contrasting Transcriptional Responses of a Virulent and an Attenuated Strain of Mycobacterium tuberculosis Infecting Macrophages

(2010) Alice H. Li et al.   PLoS One

The Population Dynamics and Control of Tuberculosis

(2010) C. Dye et al.   SCIENCE

A Defined Tuberculosis Vaccine Candidate Boosts BCG and Protects Against Multidrug-Resistant Mycobacterium tuberculosis

(2010) S. Bertholet et al.   Science Translational Medicine

Direct Visualization by Cryo-EM of the Mycobacterial Capsular Layer: A Labile Structure Containing ESX-1-Secreted Proteins

(2010) Musa Sani et al.   PLoS Pathogens

High Content Phenotypic Cell-Based Visual Screen Identifies Mycobacterium tuberculosis Acyltrehalose-Containing Glycolipids Involved in Phagosome Remodeling

(2010) Priscille Brodin et al.   PLoS Pathogens

Evidence for a rapid rate of molecular evolution at the hypervariable and immunogenic Mycobacterium tuberculosis PPE38 gene region

(2009) Christopher RE McEvoy et al.   BMC EVOLUTIONARY BIOLOGY

Strong Antibody Responses to Mycobacterium tuberculosis PE-PGRS62 Protein Are Associated with Latent and Active Tuberculosis

(2009) K. W. Koh et al.   INFECTION AND IMMUNITY

The Transcriptional Regulator Rv0485 Modulates the Expression of a pe and ppe Gene Pair and Is Required for Mycobacterium tuberculosis Virulence

(2009) R. M. Goldstone et al.   INFECTION AND IMMUNITY

The PPE18 of Mycobacterium tuberculosis Interacts with TLR2 and Activates IL-10 Induction in Macrophage

(2009) S. Nair et al.   JOURNAL OF IMMUNOLOGY

Immunoproteomic Identification of Secretory and Subcellular Protein Antigens and Functional Evaluation of the Secretome Fraction ofMycobacterium immunogenum, a Newly Recognized Species of theMycobacterium chelonae−Mycobacterium abscessusGroup

(2009) Manish K. Gupta et al.   JOURNAL OF PROTEOME RESEARCH

Degradation-resistant protein domains limit host cell processing and immune detection of mycobacteria

(2009) Kah Wee Koh et al.   MOLECULAR IMMUNOLOGY

PPE and PE_PGRS proteins ofMycobacterium marinumare transported via the type VII secretion system ESX-5

(2009) Abdallah M. Abdallah et al.   MOLECULAR MICROBIOLOGY

Defined tuberculosis vaccine, Mtb72F/AS02A, evidence of protection in cynomolgus monkeys

(2009) S. G. Reed et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intradermal immunization improves protective efficacy of a novel TB vaccine candidate

(2009) Susan L. Baldwin et al.   VACCINE

Association of Strong Immune Responses to PPE Protein Rv1168c with Active Tuberculosis

(2008) N. Khan et al.   Clinical and Vaccine Immunology

Frequent Homologous Recombination Events in Mycobacterium tuberculosis PE/PPE Multigene Families: Potential Role in Antigenic Variability

(2008) A. Karboul et al.   JOURNAL OF BACTERIOLOGY

T Cells and Tuberculosis: Beyond Interferon‐γ

(2008) Ajit Lalvani et al.   JOURNAL OF INFECTIOUS DISEASES

Evaluation of a recombinant BCG expressing antigen Ag85B and PPE protein Rv3425 from DNA segment RD11 of Mycobacterium tuberculosis in C57BL/6 mice

(2008) Jiu ling Wang et al.   MEDICAL MICROBIOLOGY AND IMMUNOLOGY

Expression of Mycobacterium tuberculosis pe_pgrs33 is repressed during stationary phase and stress conditions, and its transcription is mediated by sigma factor A

(2008) Antonio J. Vallecillo et al.   MICROBIAL PATHOGENESIS

A comparative study of host response to three Mycobacterium tuberculosis PE_PGRS proteins

(2008) P. P. Singh et al.   MICROBIOLOGY-SGM

Mycobacterium tuberculosis PE_PGRS16 and PE_PGRS26 genetic polymorphism among clinical isolates

(2008) Sarah Talarico et al.   TUBERCULOSIS

Immunogenicity and protective efficacy of tuberculosis subunit vaccines expressing PPE44 (Rv2770c)

(2008) Marta Romano et al.   VACCINE

Presence of PPE proteins in Mycobacterium avium subsp. paratuberculosis isolates and their immunogenicity in cattle

(2008) Victoria Newton et al.   VETERINARY MICROBIOLOGY

Identifying Cognate Binding Pairs among a Large Set of Paralogs: The Case of PE/PPE Proteins of Mycobacterium tuberculosis

(2008) Robert Riley et al.   PLoS Computational Biology

A protein linkage map of the ESAT-6 secretion system 1 (ESX-1) of Mycobacterium tuberculosis

(2007) Janka Teutschbein et al.   MICROBIOLOGICAL RESEARCH