GATA-dependent transcriptional and epigenetic control of cardiac lineage specification and differentiation

GATA-Binding Factor 6 Contributes to Atrioventricular Node Development and FunctionCLINICAL PERSPECTIVE

(2015) Fang Liu et al.   Circulation-Cardiovascular Genetics

GATA-Binding Factor 6 Contributes to Atrioventricular Node Development and FunctionCLINICAL PERSPECTIVE

(2015) Fang Liu et al.   Circulation-Cardiovascular Genetics

A mutation in the Kozak sequence ofGATA4hampers translation in a family with atrial septal defects

(2014) Rajiv A. Mohan et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

A Large Permissive Regulatory Domain Exclusively Controls Tbx3 Expression in the Cardiac Conduction System

(2014) Jan Hendrik van Weerd et al.   CIRCULATION RESEARCH

A CRISPR view of development

(2014) Melissa M. Harrison et al.   GENES & DEVELOPMENT

Pioneer transcription factors in cell reprogramming

(2014) Makiko Iwafuchi-Doi et al.   GENES & DEVELOPMENT

Disruption of myocardial Gata4 and Tbx5 results in defects in cardiomyocyte proliferation and atrioventricular septation

(2014) Chaitali Misra et al.   HUMAN MOLECULAR GENETICS

Carboxy terminus of GATA4 transcription factor is required for its cardiogenic activity and interaction with CDK4

(2014) Joseph M. Gallagher et al.   MECHANISMS OF DEVELOPMENT

Mechanism governing a stem cell-generating cis-regulatory element

(2014) R. Sanalkumar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sequential histone-modifying activities determine the robustness of transdifferentiation

(2014) S. Zuryn et al.   SCIENCE

Dynamic GATA4 enhancers shape the chromatin landscape central to heart development and disease

(2014) Aibin He et al.   Nature Communications

GATA-dependent regulatory switches establish atrioventricular canal specificity during heart development

(2014) Sonia Stefanovic et al.   Nature Communications

Programming and Isolation of Highly Pure Physiologically and Pharmacologically Functional Sinus-Nodal Bodies from Pluripotent Stem Cells

(2014) Julia Jeannine Jung et al.   Stem Cell Reports

Genetics of Congenital Heart Disease

(2013) Akl C. Fahed et al.   CIRCULATION RESEARCH

Topology of mammalian developmental enhancers and their regulatory landscapes

(2013) Wouter de Laat et al.   NATURE

De novo mutations in histone-modifying genes in congenital heart disease

(2013) Samir Zaidi et al.   NATURE

Mechanisms and models of somatic cell reprogramming

(2013) Yosef Buganim et al.   NATURE REVIEWS GENETICS

Epistatic Rescue of Nkx2.5 Adult Cardiac Conduction Disease Phenotypes by Prospero-Related Homeobox Protein 1 and HDAC3

(2012) Catherine A. Risebro et al.   CIRCULATION RESEARCH

Inefficient Reprogramming of Fibroblasts into Cardiomyocytes Using Gata4, Mef2c, and Tbx5

(2012) Jenny X. Chen et al.   CIRCULATION RESEARCH

Combinatorial regulation of tissue specification by GATA and FOG factors

(2012) T. M. Chlon et al.   DEVELOPMENT

New developments in the second heart field

(2012) Stéphane Zaffran et al.   DIFFERENTIATION

GATA6 loss-of-function mutation in atrial fibrillation

(2012) Yi-Qing Yang et al.   European Journal of Medical Genetics

PRC2 directly methylates GATA4 and represses its transcriptional activity

(2012) A. He et al.   GENES & DEVELOPMENT

KDM6A Point Mutations Cause Kabuki Syndrome

(2012) Noriko Miyake et al.   HUMAN MUTATION

Prevalence and spectrum of GATA6 mutations associated with familial atrial fibrillation

(2012) Yi-Qing Yang et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Myocardin regulates BMP10 expression and is required for heart development

(2012) Jianhe Huang et al.   JOURNAL OF CLINICAL INVESTIGATION

Genetic variation in T-box binding element functionally affects SCN5A/SCN10A enhancer

(2012) Malou van den Boogaard et al.   JOURNAL OF CLINICAL INVESTIGATION

Mutation spectrum of the GATA4 gene in patients with idiopathic atrial fibrillation

(2012) Jun Wang et al.   MOLECULAR BIOLOGY REPORTS

Heart repair by reprogramming non-myocytes with cardiac transcription factors

(2012) Kunhua Song et al.   NATURE

Single-tube linear DNA amplification for genome-wide studies using a few thousand cells

(2012) Pattabhiraman Shankaranarayanan et al.   Nature Protocols

Cell type–specific chromatin immunoprecipitation from multicellular complex samples using BiTS-ChIP

(2012) Stefan Bonn et al.   Nature Protocols

Integration of Hi-C and ChIP-seq data reveals distinct types of chromatin linkages

(2012) Xun Lan et al.   NUCLEIC ACIDS RESEARCH

DNA Binding by GATA Transcription Factor Suggests Mechanisms of DNA Looping and Long-Range Gene Regulation

(2012) Yongheng Chen et al.   Cell Reports

Origin and development of the atrioventricular myocardial lineage: Insight into the development of accessory pathways

(2011) Wim T. J. Aanhaanen et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

Tbx2 and Tbx3 induce atrioventricular myocardial development and endocardial cushion formation

(2011) Reena Singh et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

GATA5 interacts with GATA4 and GATA6 in outflow tract development

(2011) Brigitte Laforest et al.   DEVELOPMENTAL BIOLOGY

Whole-genome chromatin profiling from limited numbers of cells using nano-ChIP-seq

(2011) Mazhar Adli et al.   Nature Protocols

The road to biological pacing

(2011) Michael R. Rosen et al.   Nature Reviews Cardiology

Co-occupancy by multiple cardiac transcription factors identifies transcriptional enhancers active in heart

(2011) A. He et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transcription factor genes Smad4 and Gata4 cooperatively regulate cardiac valve development

(2011) I. P. Moskowitz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Cardiac Transcription Network Modulated by Gata4, Mef2a, Nkx2.5, Srf, Histone Modifications, and MicroRNAs

(2011) Jenny Schlesinger et al.   PLoS Genetics

Direct Reprogramming of Fibroblasts into Functional Cardiomyocytes by Defined Factors

(2010) Masaki Ieda et al.   CELL

Developmental Origin, Growth, and Three-Dimensional Architecture of the Atrioventricular Conduction Axis of the Mouse Heart

(2010) Wim T.J. Aanhaanen et al.   CIRCULATION RESEARCH

Development of the Pacemaker Tissues of the Heart

(2010) Vincent M. Christoffels et al.   CIRCULATION RESEARCH

Hopx and Hdac2 Interact to Modulate Gata4 Acetylation and Embryonic Cardiac Myocyte Proliferation

(2010) Chinmay M. Trivedi et al.   DEVELOPMENTAL CELL

Characterization and In Vivo Pharmacological Rescue of a Wnt2-Gata6 Pathway Required for Cardiac Inflow Tract Development

(2010) Ying Tian et al.   DEVELOPMENTAL CELL

Inducible Cx40-Cre expression in the cardiac conduction system and arterial endothelial cells

(2010) Sabrina Beyer et al.   GENESIS

A novel GATA6 mutation in patients with tetralogy of Fallot or atrial septal defect

(2010) Xiaoping Lin et al.   JOURNAL OF HUMAN GENETICS

Characterization of an antagonistic switch between histone H3 lysine 27 methylation and acetylation in the transcriptional regulation of Polycomb group target genes

(2010) Diego Pasini et al.   NUCLEIC ACIDS RESEARCH

An endocardial pathway involving Tbx5, Gata4, and Nos3 required for atrial septum formation

(2010) M. Nadeau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tbx20 Interacts With Smads to Confine Tbx2 Expression to the Atrioventricular Canal

(2009) Reena Singh et al.   CIRCULATION RESEARCH

The Tbx2 + Primary Myocardium of the Atrioventricular Canal Forms the Atrioventricular Node and the Base of the Left Ventricle

(2009) Wim T.J. Aanhaanen et al.   CIRCULATION RESEARCH

Cx30.2 enhancer analysis identifies Gata4 as a novel regulator of atrioventricular delay

(2009) N. V. Munshi et al.   DEVELOPMENT

Gata4andGata5Cooperatively Regulate Cardiac Myocyte Proliferation in Mice

(2009) Manvendra K. Singh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Insights into GATA-1-Mediated Gene Activation versus Repression via Genome-wide Chromatin Occupancy Analysis

(2009) Ming Yu et al.   MOLECULAR CELL

GATA6 mutations cause human cardiac outflow tract defects by disrupting semaphorin-plexin signaling

(2009) K. Kodo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SCL and associated proteins distinguish active from repressive GATA transcription factor complexes

(2008) T. Tripic et al.   BLOOD

Letter by Anderson et al Regarding Article, “Abnormal Conduction and Morphology in the Atrioventricular Node of Mice With Atrioventricular Canal–Targeted Deletion of Alk3/Bmpr1a Receptor”

(2008) R.H. Anderson et al.   CIRCULATION

Loss of both GATA4 and GATA6 blocks cardiac myocyte differentiation and results in acardia in mice

(2008) Roong Zhao et al.   DEVELOPMENTAL BIOLOGY

Interaction of Gata4 and Gata6 with Tbx5 is critical for normal cardiac development

(2008) Meenakshi Maitra et al.   DEVELOPMENTAL BIOLOGY

Real time monitoring of BMP Smads transcriptional activity during mouse development

(2008) Rui M. Monteiro et al.   GENESIS

GATA4 Is a Direct Transcriptional Activator of Cyclin D2 and Cdk4 and Is Required for Cardiomyocyte Proliferation in Anterior Heart Field-Derived Myocardium

(2008) A. Rojas et al.   MOLECULAR AND CELLULAR BIOLOGY

Exchange of GATA Factors Mediates Transitions in Looped Chromatin Organization at a Developmentally Regulated Gene Locus

(2008) Huie Jing et al.   MOLECULAR CELL

The developmental genetics of congenital heart disease

(2008) Benoit G. Bruneau   NATURE

Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds

(2008) Danwei Huangfu et al.   NATURE BIOTECHNOLOGY