Genetic variation in T-box binding element functionally affects SCN5A/SCN10A enhancer

MEME-ChIP: motif analysis of large DNA datasets

(2011) Philip Machanick et al.   BIOINFORMATICS

Developmental aspects of cardiac arrhythmogenesis

(2011) A. V. Postma et al.   CARDIOVASCULAR RESEARCH

Sox4 mediates Tbx3 transcriptional regulation of the gap junction protein Cx43

(2011) C. J. J. Boogerd et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Tbx2 and Tbx3 induce atrioventricular myocardial development and endocardial cushion formation

(2011) Reena Singh et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Informatic and Functional Approaches to Identifying a Regulatory Region for the Cardiac Sodium Channel

(2011) Thomas C. Atack et al.   CIRCULATION RESEARCH

Phenotypical Manifestations of Mutations in the Genes Encoding Subunits of the Cardiac Sodium Channel

(2011) Arthur A.M. Wilde et al.   CIRCULATION RESEARCH

Molecular Analysis of Patterning of Conduction Tissues in the Developing Human Heart

(2011) Aleksander Sizarov et al.   Circulation-Arrhythmia and Electrophysiology

Tbx20 regulates a genetic program essential to adult mouse cardiomyocyte function

(2011) Tao Shen et al.   JOURNAL OF CLINICAL INVESTIGATION

Large-scale discovery of enhancers from human heart tissue

(2011) Dalit May et al.   NATURE GENETICS

ENCODE whole-genome data in the UCSC Genome Browser: update 2012

(2011) K. R. Rosenbloom et al.   NUCLEIC ACIDS RESEARCH

Hypermorphic mutation of the voltage-gated sodium channel encoding gene Scn10a causes a dramatic stimulus-dependent neurobehavioral phenotype

(2011) A. L. Blasius et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lethal arrhythmias in Tbx3-deficient mice reveal extreme dosage sensitivity of cardiac conduction system function and homeostasis

(2011) D. U. Frank et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Co-occupancy by multiple cardiac transcription factors identifies transcriptional enhancers active in heart

(2011) A. He et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome-Wide Association Studies of the PR Interval in African Americans

(2011) J. Gustav Smith et al.   PLoS Genetics

Development of the Pacemaker Tissues of the Heart

(2010) Vincent M. Christoffels et al.   CIRCULATION RESEARCH

Chromatin remodeling in heart development

(2010) Benoit G Bruneau   CURRENT OPINION IN GENETICS & DEVELOPMENT

An 8q24 gene desert variant associated with prostate cancer risk confers differential in vivo activity to a MYC enhancer

(2010) N. F. Wasserman et al.   GENOME RESEARCH

ChIP-Seq identification of weakly conserved heart enhancers

(2010) Matthew J Blow et al.   NATURE GENETICS

Several common variants modulate heart rate, PR interval and QRS duration

(2010) Hilma Holm et al.   NATURE GENETICS

Genome-wide association study identifies a susceptibility locus at 21q21 for ventricular fibrillation in acute myocardial infarction

(2010) Connie R Bezzina et al.   NATURE GENETICS

Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction

(2010) Nona Sotoodehnia et al.   NATURE GENETICS

Genome-wide association study of PR interval

(2010) Arne Pfeufer et al.   NATURE GENETICS

Genetic variation in SCN10A influences cardiac conduction

(2010) John C Chambers et al.   NATURE GENETICS

Early management of atrial fibrillation: from imaging to drugs to ablation

(2010) Ashok J. Shah et al.   Nature Reviews Cardiology

Genome-wide assessment of differential roles for p300 and CBP in transcription regulation

(2010) Y. F. M. Ramos et al.   NUCLEIC ACIDS RESEARCH

Five-Vertebrate ChIP-seq Reveals the Evolutionary Dynamics of Transcription Factor Binding

(2010) D. Schmidt et al.   SCIENCE

Protein interactions at the heart of cardiac chamber formation

(2009) Cornelis J.J. Boogerd et al.   ANNALS OF ANATOMY-ANATOMISCHER ANZEIGER

The cardiac sodium channel displays differential distribution in the conduction system and transmural heterogeneity in the murine ventricular myocardium

(2009) C. A. Remme et al.   BASIC RESEARCH IN CARDIOLOGY

Specification of the Cardiac Conduction System by Transcription Factors

(2009) Cathy J. Hatcher et al.   CIRCULATION RESEARCH

Developmental Basis for Electrophysiological Heterogeneity in the Ventricular and Outflow Tract Myocardium As a Substrate for Life-Threatening Ventricular Arrhythmias

(2009) Bastiaan J.D. Boukens et al.   CIRCULATION RESEARCH

Gene Expression Profiling of the Forming Atrioventricular Node Using a Novel Tbx3 -Based Node-Specific Transgenic Reporter

(2009) Thomas Horsthuis et al.   CIRCULATION RESEARCH

Zebrafish enhancer detection (ZED) vector: A new tool to facilitate transgenesis and the functional analysis ofcis-regulatory regions in zebrafish

(2009) José Bessa et al.   DEVELOPMENTAL DYNAMICS

Genomic views of distant-acting enhancers

(2009) Axel Visel et al.   NATURE

ChIP-seq accurately predicts tissue-specific activity of enhancers

(2009) Axel Visel et al.   NATURE

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Sodium channel mutations and arrhythmias

(2009) Yanfei Ruan et al.   Nature Reviews Cardiology

ChIP–seq: advantages and challenges of a maturing technology

(2009) Peter J. Park   NATURE REVIEWS GENETICS

Genomewide Association Studies and Human Disease

(2009) John Hardy et al.   NEW ENGLAND JOURNAL OF MEDICINE

Tissue distribution and subcellular localization of the cardiac sodium channel during mouse heart development

(2008) Jorge N. Domínguez et al.   CARDIOVASCULAR RESEARCH

Transcription Factor Tbx3 Is Required for the Specification of the Atrioventricular Conduction System

(2008) Martijn L. Bakker et al.   CIRCULATION RESEARCH

Formation of the Sinus Node Head and Differentiation of Sinus Node Myocardium Are Independently Regulated by Tbx18 and Tbx3

(2008) Cornelia Wiese et al.   CIRCULATION RESEARCH

The developmental genetics of congenital heart disease

(2008) Benoit G. Bruneau   NATURE

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

(2008) Da Wei Huang et al.   NUCLEIC ACIDS RESEARCH

Genesis and Regulation of the Heart Automaticity

(2008) Matteo E. Mangoni et al.   PHYSIOLOGICAL REVIEWS