Sonic hedgehog patterning during cerebellar development

Heterogeneity and Bipotency of Astroglial-Like Cerebellar Progenitors along the Interneuron and Glial Lineages

(2015) E. Parmigiani et al.   JOURNAL OF NEUROSCIENCE

Exogenous Sonic Hedgehog Modulates the Pool of GABAergic Interneurons During Cerebellar Development

(2014) A. De Luca et al.   CEREBELLUM

Growth and differentiation factor 10 (Gdf10) is involved in Bergmann glial cell development underShhregulation

(2014) Nora Mecklenburg et al.   GLIA

Germline Mutations inSUFUCause Gorlin Syndrome–Associated Childhood Medulloblastoma and Redefine the Risk Associated WithPTCH1Mutations

(2014) Miriam J. Smith et al.   JOURNAL OF CLINICAL ONCOLOGY

Specification of Spatial Identities of Cerebellar Neuron Progenitors by Ptf1a and Atoh1 for Proper Production of GABAergic and Glutamatergic Neurons

(2014) M. Yamada et al.   JOURNAL OF NEUROSCIENCE

Temporal identity transition from Purkinje cell progenitors to GABAergic interneuron progenitors in the cerebellum

(2014) Yusuke Seto et al.   Nature Communications

Kif3a is necessary for initiation and maintenance of medulloblastoma

(2013) Monique T. Barakat et al.   CARCINOGENESIS

Interaction of PACAP with Sonic hedgehog reveals complex regulation of the Hedgehog pathway by PKA

(2013) Pawel Niewiadomski et al.   CELLULAR SIGNALLING

Signaling mechanisms of non-conventional axon guidance cues: the Shh, BMP and Wnt morphogens

(2013) Patricia T Yam et al.   CURRENT OPINION IN NEUROBIOLOGY

The Purkinje Neuron Acts as a Central Regulator of Spatially and Functionally Distinct Cerebellar Precursors

(2013) Jonathan T. Fleming et al.   DEVELOPMENTAL CELL

A population of Nestin-expressing progenitors in the cerebellum exhibits increased tumorigenicity

(2013) Peng Li et al.   NATURE NEUROSCIENCE

Origin, lineage and function of cerebellar glia

(2013) Annalisa Buffo et al.   PROGRESS IN NEUROBIOLOGY

Canonical TGF-β Pathway Activity Is a Predictor of SHH-Driven Medulloblastoma Survival and Delineates Putative Precursors in Cerebellar Development

(2012) Donya Aref et al.   BRAIN PATHOLOGY

Megalin mediates the influence of sonic hedgehog on oligodendrocyte precursor cell migration and proliferation during development

(2012) María Cristina Ortega et al.   GLIA

High Frequency of Germline SUFU Mutations in Children With Desmoplastic/Nodular Medulloblastoma Younger Than 3 Years of Age

(2012) Laurence Brugières et al.   JOURNAL OF CLINICAL ONCOLOGY

Subgroup-specific structural variation across 1,000 medulloblastoma genomes

(2012) Paul A. Northcott et al.   NATURE

Purkinje Cell Maturation Participates in the Control of Oligodendrocyte Differentiation: Role of Sonic Hedgehog and Vitronectin

(2012) Lamia Bouslama-Oueghlani et al.   PLoS One

Analysis of human samples reveals impaired SHH-dependent cerebellar development in Joubert syndrome/Meckel syndrome

(2012) A. Aguilar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pediatric and adult sonic hedgehog medulloblastomas are clinically and molecularly distinct

(2011) Paul A. Northcott et al.   ACTA NEUROPATHOLOGICA

Molecular subgroups of medulloblastoma: the current consensus

(2011) Michael D. Taylor et al.   ACTA NEUROPATHOLOGICA

Boc and Gas1 Each Form Distinct Shh Receptor Complexes with Ptch1 and Are Required for Shh-Mediated Cell Proliferation

(2011) Luisa Izzi et al.   DEVELOPMENTAL CELL

GLI2 Is a Potential Therapeutic Target in Pediatric Medulloblastoma

(2011) Pawel Buczkowicz et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Suppressor of Fused Controls Mid-Hindbrain Patterning and Cerebellar Morphogenesis via GLI3 Repressor

(2011) J. J. Kim et al.   JOURNAL OF NEUROSCIENCE

Ascl1 Genetics Reveals Insights into Cerebellum Local Circuit Assembly

(2011) A. Sudarov et al.   JOURNAL OF NEUROSCIENCE

Sonic Hedgehog Dependent Phosphorylation by CK1α and GRK2 Is Required for Ciliary Accumulation and Activation of Smoothened

(2011) Yongbin Chen et al.   PLOS BIOLOGY

Hedgehog signaling update

(2010) M. Michael Cohen Jr.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

A mechanism for vertebrate Hedgehog signaling: recruitment to cilia and dissociation of SuFu–Gli protein complexes

(2010) Hanna Tukachinsky et al.   JOURNAL OF CELL BIOLOGY

Medulloblastoma Comprises Four Distinct Molecular Variants

(2010) Paul A. Northcott et al.   JOURNAL OF CLINICAL ONCOLOGY

Sonic Hedgehog Regulates Discrete Populations of Astrocytes in the Adult Mouse Forebrain

(2010) A. D. R. Garcia et al.   JOURNAL OF NEUROSCIENCE

The primary cilium: a signalling centre during vertebrate development

(2010) Sarah C. Goetz et al.   NATURE REVIEWS GENETICS

Transventricular delivery of Sonic hedgehog is essential to cerebellar ventricular zone development

(2010) X. Huang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SHH Pathway and Cerebellar Development

(2009) Catherine Vaillant et al.   CEREBELLUM

BMP7 and SHH regulate Pax2 in mouse retinal astrocytes by relieving TLX repression

(2009) Rachna Sehgal et al.   DEVELOPMENTAL BIOLOGY

Origins and control of the differentiation of inhibitory interneurons and glia in the cerebellum

(2009) Piercesare Grimaldi et al.   DEVELOPMENTAL BIOLOGY

Laminar Fate and Phenotype Specification of Cerebellar GABAergic Interneurons

(2009) K. Leto et al.   JOURNAL OF NEUROSCIENCE

Trafficking, development and hedgehog

(2009) Fiona Simpson et al.   MECHANISMS OF DEVELOPMENT

The Smo/Smo Model: Hedgehog-Induced Medulloblastoma with 90% Incidence and Leptomeningeal Spread

(2008) B. A. Hatton et al.   CANCER RESEARCH

Cerebellar development and disease

(2008) Kathleen J Millen et al.   CURRENT OPINION IN NEUROBIOLOGY

Primary cilia are required for cerebellar development and Shh-dependent expansion of progenitor pool

(2008) N. Spassky et al.   DEVELOPMENTAL BIOLOGY

Hedgehog: functions and mechanisms

(2008) M. Varjosalo et al.   GENES & DEVELOPMENT

Besides Purkinje cells and granule neurons: an appraisal of the cell biology of the interneurons of the cerebellar cortex

(2008) Karl Schilling et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Cerebellar granule cells: Insights into proliferation, differentiation, and role in medulloblastoma pathogenesis

(2008) Hourinaz Behesti et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Defining a role for Sonic hedgehog pathway activation in desmoplastic medulloblastoma by identifying GLI1 target genes

(2008) Joon Won Yoon et al.   INTERNATIONAL JOURNAL OF CANCER

Integrated Genomics Identifies Five Medulloblastoma Subtypes with Distinct Genetic Profiles, Pathway Signatures and Clinicopathological Features

(2008) Marcel Kool et al.   PLoS One

Fine-tuning of cell signaling by glypicans

(2007) A. Fico et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Disruption of the PACAP gene promotes medulloblastoma in ptc1 mutant mice

(2007) Vincent Lelievre et al.   DEVELOPMENTAL BIOLOGY