Canonical TGF-β Pathway Activity Is a Predictor of SHH-Driven Medulloblastoma Survival and Delineates Putative Precursors in Cerebellar Development

Molecular subgroups of medulloblastoma: an international meta-analysis of transcriptome, genetic aberrations, and clinical data of WNT, SHH, Group 3, and Group 4 medulloblastomas

(2012) Marcel Kool et al.   ACTA NEUROPATHOLOGICA

MiRNA-335 suppresses neuroblastoma cell invasiveness by direct targeting of multiple genes from the non-canonical TGF-β signalling pathway

(2012) Jennifer Lynch et al.   CARCINOGENESIS

c-Myc expression and MEK1-induced Erk2 nuclear localization are required for TGF-beta induced epithelial–mesenchymal transition and invasion in prostate cancer

(2012) Michael D. Amatangelo et al.   CARCINOGENESIS

Clonal selection drives genetic divergence of metastatic medulloblastoma

(2012) Xiaochong Wu et al.   NATURE

Medulloblastoma: clinicopathological correlates of SHH, WNT, and non-SHH/WNT molecular subgroups

(2011) David W. Ellison et al.   ACTA NEUROPATHOLOGICA

Rapid, reliable, and reproducible molecular sub-grouping of clinical medulloblastoma samples

(2011) Paul A. Northcott et al.   ACTA NEUROPATHOLOGICA

Molecular subgroups of medulloblastoma: the current consensus

(2011) Michael D. Taylor et al.   ACTA NEUROPATHOLOGICA

Contrasting Behavior of the p18INK4c and p16INK4a Tumor Suppressors in Both Replicative and Oncogene-Induced Senescence

(2011) S. Gagrica et al.   CANCER RESEARCH

Medulloblastomas

(2011) Franck Bourdeaut et al.   CURRENT OPINION IN ONCOLOGY

MicroRNA-21 suppression impedes medulloblastoma cell migration

(2011) Eveline Grunder et al.   EUROPEAN JOURNAL OF CANCER

Role of TGF-β and the Tumor Microenvironment During Mammary Tumorigenesis

(2011) MOLLY A. TAYLOR et al.   GENE EXPRESSION

Smad2 Protein Disruption in the Central Nervous System Leads to Aberrant Cerebellar Development and Early Postnatal Ataxia in Mice

(2011) Lixiang Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Predicting Relapse in Patients With Medulloblastoma by Integrating Evidence From Clinical and Genomic Features

(2011) Pablo Tamayo et al.   JOURNAL OF CLINICAL ONCOLOGY

Adult Medulloblastoma Comprises Three Major Molecular Variants

(2011) Marc Remke et al.   JOURNAL OF CLINICAL ONCOLOGY

Noncanonical TGF-β Signaling During Mammary Tumorigenesis

(2011) Jenny G. Parvani et al.   JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA

Bone morphogenetic proteins induce apoptosis in multiple myeloma cells by Smad-dependent repression of MYC

(2011) T Holien et al.   LEUKEMIA

Bone morphogenetic protein-7 is a MYC target with prosurvival functions in childhood medulloblastoma

(2011) G Fiaschetti et al.   ONCOGENE

Development and cancer of the cerebellum

(2011) Mary E. Hatten et al.   TRENDS IN NEUROSCIENCES

Molecular diagnostics of CNS embryonal tumors

(2010) Stefan M. Pfister et al.   ACTA NEUROPATHOLOGICA

Adult and Pediatric Medulloblastomas Are Genetically Distinct and Require Different Algorithms for Molecular Risk Stratification

(2010) Andrey Korshunov et al.   JOURNAL OF CLINICAL ONCOLOGY

Integrative Genomic Analysis of Medulloblastoma Identifies a Molecular Subgroup That Drives Poor Clinical Outcome

(2010) Yoon-Jae Cho et al.   JOURNAL OF CLINICAL ONCOLOGY

Medulloblastoma Comprises Four Distinct Molecular Variants

(2010) Paul A. Northcott et al.   JOURNAL OF CLINICAL ONCOLOGY

Subtypes of medulloblastoma have distinct developmental origins

(2010) Paul Gibson et al.   NATURE

Smad2/3 activities are required for induction and patterning of the neuroectoderm in zebrafish

(2009) Shunji Jia et al.   DEVELOPMENTAL BIOLOGY

The TGF-β paradox in human cancer: an update

(2009) Maozhen Tian et al.   Future Oncology

The Origins of Medulloblastoma Subtypes

(2008) Richard J. Gilbertson et al.   Annual Review of Pathology-Mechanisms of Disease

The Smo/Smo Model: Hedgehog-Induced Medulloblastoma with 90% Incidence and Leptomeningeal Spread

(2008) B. A. Hatton et al.   CANCER RESEARCH

Molecular Risk Stratification of Medulloblastoma Patients Based on Immunohistochemical Analysis of MYC, LDHB, and CCNB1 Expression

(2008) T. de Haas et al.   CLINICAL CANCER RESEARCH

Enhanced neurogenesis from neural progenitor cells with G1/S-phase cell cycle arrest is mediated by transforming growth factor β1

(2008) Sachiyo Misumi et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Post-transcriptional down-regulation of Atoh1/Math1 by bone morphogenic proteins suppresses medulloblastoma development

(2008) H. Zhao et al.   GENES & DEVELOPMENT

Integrated Genomics Identifies Five Medulloblastoma Subtypes with Distinct Genetic Profiles, Pathway Signatures and Clinicopathological Features

(2008) Marcel Kool et al.   PLoS One

Nuclear localization of Cdk5 is a key determinant in the postmitotic state of neurons

(2008) J. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA