Boron Neutron Capture Therapy Eliminates Radioresistant Liver Cancer Cells by Targeting DNA Damage and Repair Responses

NEAT1 Confers Radioresistance to Hepatocellular Carcinoma Cells by Inducing Autophagy through GABARAP

(2022) Hiromi Sakaguchi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

An emerging role of radiation‑induced exosomes in hepatocellular carcinoma progression and radioresistance (Review)

(2022) Qing Fan et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Immunotherapies for hepatocellular carcinoma

(2021) Josep M. Llovet et al.   Nature Reviews Clinical Oncology

Immunotherapy for Hepatocellular Carcinoma: Current Status and Future Prospects

(2021) Zhuoyan Liu et al.   Frontiers in Immunology

Clinical and Preclinical Outcomes of Combining Targeted Therapy With Radiotherapy

(2021) May Elbanna et al.   Frontiers in Oncology

Clustered DNA Double-Strand Breaks: Biological Effects and Relevance to Cancer Radiotherapy

(2020) Jac A. Nickoloff et al.   Genes

Suitability of boric acid as a boron drug for boron neutron capture therapy for hepatoma

(2020) Yi-Hsuan Hung et al.   APPLIED RADIATION AND ISOTOPES

The effects of proliferation status and cell cycle phase on the responses of single cells to chemotherapy

(2020) Adrián E. Granada et al.   MOLECULAR BIOLOGY OF THE CELL

Phase I trial of WEE1 inhibition with chemotherapy and radiotherapy as adjuvant treatment, and a window of opportunity trial with cisplatin in patients with head and neck cancer: theWISTERIAtrial protocol

(2020) Anthony Kong et al.   BMJ Open

The Determinant of DNA Repair Pathway Choices in Ionising Radiation-Induced DNA Double-Strand Breaks

(2020) Lei Zhao et al.   Biomed Research International

Boron neutron capture therapy: Current status and future perspectives

(2020) Mayya Alexandrovna Dymova et al.   Cancer Communications

Current Treatment Landscape for Advanced Hepatocellular Carcinoma: Patient Outcomes and the Impact on Quality of Life

(2019) Daneng Li et al.   Cancers

The Cell Cycle G2/M Block Is an Indicator of Cellular Radiosensitivity

(2019) Chang Liu et al.   Dose-Response

Dose Escalation Trial of the Wee1 Inhibitor Adavosertib (AZD1775) in Combination With Gemcitabine and Radiation for Patients With Locally Advanced Pancreatic Cancer

(2019) Kyle C. Cuneo et al.   JOURNAL OF CLINICAL ONCOLOGY

Boron neutron capture therapy of cancer: Critical issues and future prospects

(2019) Tai‐Ze Yuan et al.   Thoracic Cancer

Analysis of DNA Damage Responses After Boric Acid-mediated Boron Neutron Capture Therapy in Hepatocellular Carcinoma

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Boron agents for neutron capture therapy

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How cells ensure correct repair of DNA double-strand breaks

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Hepatocellular carcinoma

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In vitro studies of DNA damage and repair mechanisms induced by BNCT in a poorly differentiated thyroid carcinoma cell line

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Mechanisms of resistance to chemotherapy and radiotherapy in hepatocellular carcinoma

(2018) Jiapei Guo et al.   Translational Cancer Research

State-of-the-art strategies for targeting the DNA damage response in cancer

(2018) Patrick G. Pilié et al.   Nature Reviews Clinical Oncology

Simultaneous induction of dispersed and clustered DNA lesions compromises DNA damage response in human peripheral blood lymphocytes

(2018) Lei Cheng et al.   PLoS One

Effect of low- and high-linear energy transfer radiation on in vitro and orthotopic in vivo models of osteosarcoma by activation of caspase-3 and -9

(2017) Eun Ho Kim et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

ATM, ATR, and DNA-PK: The Trinity at the Heart of the DNA Damage Response

(2017) Andrew N. Blackford et al.   MOLECULAR CELL

Egr-1 regulates irradiation-induced autophagy through Atg4B to promote radioresistance in hepatocellular carcinoma cells

(2017) W-x Peng et al.   Oncogenesis

RAD51 Is a Selective DNA Repair Target to Radiosensitize Glioma Stem Cells

(2017) Harry O. King et al.   Stem Cell Reports

Perspectives on the combination of radiotherapy and targeted therapy with DNA repair inhibitors in the treatment of pancreatic cancer

(2016) Shih-Hung Yang et al.   WORLD JOURNAL OF GASTROENTEROLOGY

The DNA Damage Response: Implications for Tumor Responses to Radiation and Chemotherapy

(2015) Michael Goldstein et al.   Annual Review of Medicine

Autoradiographic and histopathological studies of boric acid-mediated BNCT in hepatic VX2 tumor-bearing rabbits: Specific boron retention and damage in tumor and tumor vessels

(2015) C.H. Yang et al.   APPLIED RADIATION AND ISOTOPES

DNA damage checkpoint recovery and cancer development

(2015) Haiyong Wang et al.   EXPERIMENTAL CELL RESEARCH

Mechanisms and Consequences of Double-Strand DNA Break Formation in Chromatin

(2015) Wendy J. Cannan et al.   JOURNAL OF CELLULAR PHYSIOLOGY

A Phase I/II Study of Bortezomib in Combination with Paclitaxel, Carboplatin, and Concurrent Thoracic Radiation Therapy for Non–Small-Cell Lung Cancer: North Central Cancer Treatment Group (NCCTG)-N0321

(2015) Yujie Zhao et al.   Journal of Thoracic Oncology

DNA damage induced by boron neutron capture therapy is partially repaired by DNA ligase IV

(2015) Natsuko Kondo et al.   RADIATION AND ENVIRONMENTAL BIOPHYSICS

Understanding Cancer Development Processes after HZE-Particle Exposure: Roles of ROS, DNA Damage Repair and Inflammation

(2015) D. M. Sridharan et al.   RADIATION RESEARCH

AKT-mediated enhanced aerobic glycolysis causes acquired radioresistance by human tumor cells

(2014) Tsutomu Shimura et al.   RADIOTHERAPY AND ONCOLOGY

The complexity of DNA double strand breaks is a critical factor enhancing end-resection

(2013) Hirohiko Yajima et al.   DNA REPAIR

High linear-energy-transfer radiation can overcome radioresistance of glioma stem-like cells to low linear-energy-transfer radiation

(2013) Y. Hirota et al.   JOURNAL OF RADIATION RESEARCH

Use of the γ-H2AX Assay to Investigate DNA Repair Dynamics Following Multiple Radiation Exposures

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The DNA damage response and cancer therapy

(2012) Christopher J. Lord et al.   NATURE

Increased Artemis levels confer radioresistance to both high and low LET radiation exposures

(2012) Deepa M Sridharan et al.   Radiation Oncology

Factors determining DNA double-strand break repair pathway choice in G2 phase

(2011) Atsushi Shibata et al.   EMBO JOURNAL

Repair of DNA damage induced by accelerated heavy ions-A mini review

(2011) Ryuichi Okayasu   INTERNATIONAL JOURNAL OF CANCER

Radiation-generated Short DNA Fragments May Perturb Non-homologous End-joining and Induce Genomic Instability

(2011) Dalong PANG et al.   JOURNAL OF RADIATION RESEARCH

DNA double-strand break induction in Ku80-deficient CHO cells following Boron Neutron Capture Reaction

(2011) Yuko Kinashi et al.   Radiation Oncology

The DNA Damage Response: Making It Safe to Play with Knives

(2010) Alberto Ciccia et al.   MOLECULAR CELL

Characteristics of DNA-binding proteins determine the biological sensitivity to high-linear energy transfer radiation

(2010) H. Wang et al.   NUCLEIC ACIDS RESEARCH

Inducible response required for repair of low-dose radiation damage in human fibroblasts

(2010) S. Grudzenski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Suitability of boron carriers for BNCT: Accumulation of boron in malignant and normal liver cells after treatment with BPA, BSH and BA

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