The effects of proliferation status and cell cycle phase on the responses of single cells to chemotherapy

Real-time dynamics of mutagenesis reveal the chronology of DNA repair and damage tolerance responses in single cells

(2018) Stephan Uphoff   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Anticancer chemotherapy and radiotherapy trigger both non-cell-autonomous and cell-autonomous death

(2018) Isabelle Martins et al.   Cell Death & Disease

Single-Cell Tracking of A549 Lung Cancer Cells Exposed to a Marine Toxin Reveals Correlations in Pedigree Tree Profiles

(2018) Mónica Suárez Korsnes et al.   Frontiers in Oncology

Fluctuations in p53 Signaling Allow Escape from Cell-Cycle Arrest

(2018) José Reyes et al.   MOLECULAR CELL

Inheritance of OCT4 predetermines fate choice in human embryonic stem cells

(2018) Samuel C Wolff et al.   Molecular Systems Biology

In situ immune response and mechanisms of cell damage in central nervous system of fatal cases microcephaly by Zika virus

(2018) Raimunda S. S. Azevedo et al.   Scientific Reports

Hidden heterogeneity and circadian-controlled cell fate inferred from single cell lineages

(2018) Shaon Chakrabarti et al.   Nature Communications

The Partial Information Decomposition of Generative Neural Network Models

(2017) Tycho Tax et al.   Entropy

Endogenous Replication Stress in Mother Cells Leads to Quiescence of Daughter Cells

(2017) Mansi Arora et al.   Cell Reports

Cell-Cycle Position of Single MYC-Driven Cancer Cells Dictates Their Susceptibility to a Chemotherapeutic Drug

(2017) Tatsiana Ryl et al.   Cell Systems

Cell-to-Cell Variation in p53 Dynamics Leads to Fractional Killing

(2016) Andrew L. Paek et al.   CELL

The Role of Proliferation in Determining Response to Neoadjuvant Chemotherapy in Breast Cancer: A Gene Expression-Based Meta-Analysis

(2016) D. G. Stover et al.   CLINICAL CANCER RESEARCH

Growth rate inhibition metrics correct for confounders in measuring sensitivity to cancer drugs

(2016) Marc Hafner et al.   NATURE METHODS

Intrinsic TGF-β2-triggered SDF-1-CXCR4 signaling axis is crucial for drug resistance and a slow-cycling state in bone marrow-disseminated tumor cells

(2015) Takuya Nakamura et al.   Oncotarget

Spatial–temporal FUCCI imaging of each cell in a tumor demonstrates locational dependence of cell cycle dynamics and chemoresponsiveness

(2014) Shuya Yano et al.   CELL CYCLE

Information transfer by leaky, heterogeneous, protein kinase signaling systems

(2014) M. Voliotis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Accurate information transmission through dynamic biochemical signaling networks

(2014) J. Selimkhanov et al.   SCIENCE

Synergy, redundancy, and multivariate information measures: an experimentalist’s perspective

(2013) Nicholas Timme et al.   JOURNAL OF COMPUTATIONAL NEUROSCIENCE

Correction: High Weight Loss during Radiation Treatment Changes the Prognosis in Under-/Normal Weight Nasopharyngeal Carcinoma Patients for the Worse: A Retrospective Analysis of 2433 Cases

(2013) Lu-Jun Shen et al.   PLoS One

Defining the mode of tumour growth by clonal analysis

(2012) Gregory Driessens et al.   NATURE

Telomeric DNA damage is irreparable and causes persistent DNA-damage-response activation

(2012) Marzia Fumagalli et al.   NATURE CELL BIOLOGY

Fractional proliferation: a method to deconvolve cell population dynamics from single-cell data

(2012) Darren R Tyson et al.   NATURE METHODS

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

The impact of S- and G2-checkpoint response on the fidelity of G1-arrest by cisplatin and its comparison to a non-cross-resistant platinum(IV) analog

(2011) Guangan He et al.   GYNECOLOGIC ONCOLOGY

The proliferation rate paradox in antimitotic chemotherapy

(2011) Timothy J. Mitchison   MOLECULAR BIOLOGY OF THE CELL

Origins of regulated cell-to-cell variability

(2011) Berend Snijder et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Molecular mechanisms of cisplatin resistance

(2011) L Galluzzi et al.   ONCOGENE

A Chromatin-Mediated Reversible Drug-Tolerant State in Cancer Cell Subpopulations

(2010) Sreenath V. Sharma et al.   CELL

Non-genetic origins of cell-to-cell variability in TRAIL-induced apoptosis

(2009) Sabrina L. Spencer et al.   NATURE

Visualizing Spatiotemporal Dynamics of Multicellular Cell-Cycle Progression

(2008) Asako Sakaue-Sawano et al.   CELL

Quantitative Analysis of Pathways Controlling Extrinsic Apoptosis in Single Cells

(2008) John G. Albeck et al.   MOLECULAR CELL