Short-Term Omega-3 Supplementation Modulates Novel Neurovascular and Fatty Acid Metabolic Proteome Changes in the Retina and Ophthalmic Artery of Mice with Targeted Cyp2c44 Gene Deletion

Controlling litter effects to enhance rigor and reproducibility with rodent models of neurodevelopmental disorders

(2021) Jessica A. Jiménez et al.   Journal of Neurodevelopmental Disorders

Absence of Cytochrome P450-1b1 Increases Susceptibility of Pressure-Induced Axonopathy in the Murine Retinal Projection

(2021) Naseem Amirmokhtari et al.   Frontiers in Cell and Developmental Biology

The glycolytic process in endothelial cells and its implications

(2021) Susan et al.   ACTA PHARMACOLOGICA SINICA

Cyp2c44 epoxygenase-derived epoxyeicosatrienoic acids in vascular smooth muscle cells elicit vasoconstriction of the murine ophthalmic artery

(2021) Jiong Hu et al.   Scientific Reports

Dietary ω-3 polyunsaturated fatty acids are protective for myopia

(2021) Miaozhen Pan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Omega-3 and omega-6 fatty acids have distinct effects on endothelial fatty acid content and nitric oxide bioavailability

(2021) Samuel C.R. Sherratt et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Bioenergetic shift and actin cytoskeleton remodelling as acute vascular adaptive mechanisms to angiotensin II in murine retina and ophthalmic artery

(2020) Natarajan Perumal et al.   Redox Biology

Selective knockdown of hexokinase 2 in rods leads to age-related photoreceptor degeneration and retinal metabolic remodeling

(2020) Rui Zhang et al.   Cell Death & Disease

A disease causing ATLASTIN 3 mutation affects multiple endoplasmic reticulum-related pathways

(2019) Laura Behrendt et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Sample Preparation for Mass-spectrometry-based Proteomics Analysis of Ocular Microvessels

(2019) Natarajan Perumal et al.   Jove-Journal of Visualized Experiments

Dietary fatty acids promote lipid droplet diversity through seipin enrichment in an ER subdomain

(2019) Zhe Cao et al.   Nature Communications

Congenital fibrosis of the extra-ocular muscles (CFEOM) and the cranial dysinnervation disorders

(2019) Anthony J. Vivian   EYE

Retinal energy demands control vascular supply of the retina in development and disease: The role of neuronal lipid and glucose metabolism

(2018) Jean-Sébastien Joyal et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Omega-3 Fatty Acid Supplementation Improves Endothelial Function in Primary Antiphospholipid Syndrome: A Small-Scale Randomized Double-Blind Placebo-Controlled Trial

(2018) Sheylla M. Felau et al.   Frontiers in Immunology

Oral Omega-3 Supplementation Lowers Intraocular Pressure in Normotensive Adults

(2018) Laura Elizabeth Downie et al.   Translational Vision Science & Technology

Quiescent Endothelial Cells Upregulate Fatty Acid β-Oxidation for Vasculoprotection via Redox Homeostasis

(2018) Joanna Kalucka et al.   Cell Metabolism

Nutritional AMD Treatment Phase I (NAT-1): Feasibility of Oral DHA Supplementation in Age-Related Macular Degeneration

(2018) G. Querques et al.   EUROPEAN JOURNAL OF OPHTHALMOLOGY

Omega-3 fatty acids regulate plasticity in distinct hippocampal glutamatergic synapses

(2018) Sanjay Aryal et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Somatic Gene Editing of GUCY2D by AAV-CRISPR/Cas9 Alters Retinal Structure and Function in Mouse and Macaque

(2018) K. Tyler McCullough et al.   HUMAN GENE THERAPY

Effect of different concentrations of omega-3 fatty acids on stimulated THP-1 macrophages

(2017) B. Allam-Ndoul et al.   Genes and Nutrition

Changes in liver proteins of rats fed standard and high-fat and sucrose diets induced by fish omega-3 PUFAs and their combination with grape polyphenols according to quantitative proteomics

(2017) Lucía Méndez et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Role of Müller cell cytochrome P450 2c44 in murine retinal angiogenesis

(2017) Jiong Hu et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS

Effect of different concentrations of omega-3 fatty acids on stimulated THP-1 macrophages

(2017) B. Allam-Ndoul et al.   Genes and Nutrition

Compensatory Vasodilator Mechanisms in the Ophthalmic Artery of Endothelial Nitric Oxide Synthase Gene Knockout Mice

(2017) Caroline Manicam et al.   Scientific Reports

Short-Term Omega 3 Fatty Acids Treatment for Dry Eye in Young and Middle-Aged Visual Display Terminal Users

(2016) Rahul Bhargava et al.   Eye & Contact Lens-Science and Clinical Practice

The MaxQuant computational platform for mass spectrometry-based shotgun proteomics

(2016) Stefka Tyanova et al.   Nature Protocols

Structural basis for misregulation of kinesin KIF21A autoinhibition by CFEOM1 disease mutations

(2016) Sarah Bianchi et al.   Scientific Reports

The Gatekeepers in the Mouse Ophthalmic Artery: Endothelium-Dependent Mechanisms of Cholinergic Vasodilation

(2016) Caroline Manicam et al.   Scientific Reports

Dietary Marine ω-3 Fatty Acids and Incident Sight-Threatening Retinopathy in Middle-Aged and Older Individuals With Type 2 Diabetes

(2016) Aleix Sala-Vila et al.   JAMA Ophthalmology

The impact of sequence database choice on metaproteomic results in gut microbiota studies

(2016) Alessandro Tanca et al.   Microbiome

Does Short-Term Dietary Omega-3 Fatty Acid Supplementation Influence Brain Hippocampus Gene Expression of Zinc Transporter-3?

(2015) Nur Sopian et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Effective Leveraging of Targeted Search Spaces for Improving Peptide Identification in Tandem Mass Spectrometry Based Proteomics

(2015) Avinash K. Shanmugam et al.   JOURNAL OF PROTEOME RESEARCH

Proteomics-Based Metabolic Modeling Reveals That Fatty Acid Oxidation (FAO) Controls Endothelial Cell (EC) Permeability

(2015) Francesca Patella et al.   MOLECULAR & CELLULAR PROTEOMICS

Short-term supplementation of acute long-chain omega-3 polyunsaturated fatty acids may alter depression status and decrease symptomology among young adults with depression: A preliminary randomized and placebo controlled trial

(2015) Annie T. Ginty et al.   PSYCHIATRY RESEARCH

Cytochrome P450 2C8 ω3-Long-Chain Polyunsaturated Fatty Acid Metabolites Increase Mouse Retinal Pathologic Neovascularization—Brief Report

(2014) Zhuo Shao et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Cytochrome P450-generated metabolites derived from ω-3 fatty acids attenuate neovascularization

(2014) Ryoji Yanai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Analysis of the tryptic search space in UniProt databases

(2014) Emanuele Alpi et al.   PROTEOMICS

Role of dietary fish oil on nitric oxide synthase activity and oxidative status in mice red blood cells

(2014) Marcela A. Martins et al.   Food & Function

Causal analysis approaches in Ingenuity Pathway Analysis

(2013) Andreas Krämer et al.   BIOINFORMATICS

Targeting hexokinase II to mitochondria to modulate energy metabolism and reduce ischaemia-reperfusion injury in heart

(2013) Rianne Nederlof et al.   BRITISH JOURNAL OF PHARMACOLOGY

Long term effects of lutein, zeaxanthin and omega-3-LCPUFAs supplementation on optical density of macular pigment in AMD patients: the LUTEGA study

(2013) Jens Dawczynski et al.   GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

Alterations in neuronal morphology and synaptophysin expression in the rat brain as a result of changes in dietary n-6: n-3 fatty acid ratios

(2013) Toktam Hajjar et al.   Lipids in Health and Disease

Nitric oxide scavenging causes remodeling of the endoplasmic reticulum, Golgi apparatus and mitochondria in pulmonary arterial endothelial cells

(2013) Jason E. Lee et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Effects of Lutein and Docosahexaenoic Acid Supplementation on Macular Pigment Optical Density in a Randomized Controlled Trial

(2013) Alfredo García-Layana et al.   Nutrients

Alteration of Vitreal Retinoschisin Level in Human Primary Retinal Detachment

(2013) Sten Kjellström et al.   JAMA Ophthalmology

Preventive Effects of Omega-3 and Omega-6 Fatty Acids on Peroxide Mediated Oxidative Stress Responses in Primary Human Trabecular Meshwork Cells

(2012) Theofilos Tourtas et al.   PLoS One

Survey of the camel urinary proteome by shotgun proteomics using a multiple database search strategy

(2012) Abdulqader A. Alhaider et al.   PROTEOMICS

Dietary ω-3 Fatty Acid and Fish Intake and Incident Age-Related Macular Degeneration in Women

(2011) William G. Christen   ARCHIVES OF OPHTHALMOLOGY

Reducing the Genetic Risk of Age-Related Macular Degeneration With Dietary Antioxidants, Zinc, and ω-3 Fatty Acids

(2011) Lintje Ho   ARCHIVES OF OPHTHALMOLOGY

The need for littermate controls

(2011) Rikard Holmdahl et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Long-Term Preservation of Cones and Improvement in Visual Function Following Gene Therapy in a Mouse Model of Leber Congenital Amaurosis Caused by Guanylate Cyclase-1 Deficiency

(2011) Marija Mihelec et al.   HUMAN GENE THERAPY

Andromeda: A Peptide Search Engine Integrated into the MaxQuant Environment

(2011) Jürgen Cox et al.   JOURNAL OF PROTEOME RESEARCH

Genetic Variation in the CYP2C Monooxygenase Enzyme Subfamily Shows No Association With Longevity in a German Population

(2011) F. Flachsbart et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Hypoxia-inducible factor-1-dependent mechanisms of vascularization and vascular remodelling

(2010) S. Rey et al.   CARDIOVASCULAR RESEARCH

The physiological roles of phosducin: from retinal function to stress-dependent hypertension

(2010) Nadine Beetz et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Short Communication: PPARγ Mediates a Direct Antiangiogenic Effect of ω3-PUFAs in Proliferative Retinopathy

(2010) Andreas Stahl et al.   CIRCULATION RESEARCH

Cone and rod photoreceptor transplantation in models of the childhood retinopathy Leber congenital amaurosis using flow-sorted Crx-positive donor cells

(2010) J. Lakowski et al.   HUMAN MOLECULAR GENETICS

Arachidonic Acid-metabolizing Cytochrome P450 Enzymes Are Targets of ω-3 Fatty Acids

(2010) Cosima Arnold et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanisms of n-3 fatty acid-mediated development and maintenance of learning memory performance

(2010) Hui-Min Su   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Synaptophysin Expression in Rat Retina Following Acute High Intraocular Pressure

(2009) Chen Dan et al.   ACTA HISTOCHEMICA ET CYTOCHEMICA

Dietary Fatty Acids and the 10-Year Incidence of Age-Related Macular Degeneration

(2009) Jennifer S. L. Tan   ARCHIVES OF OPHTHALMOLOGY

A dietary combination of omega-3 and omega-6 polyunsaturated fatty acids is more efficient than single supplementations in the prevention of retinal damage induced by elevation of intraocular pressure in rats

(2009) Coralie Schnebelen et al.   GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

Axonal Transport Defects in Neurodegenerative Diseases

(2009) G. A. Morfini et al.   JOURNAL OF NEUROSCIENCE

TGF-β Is Required for Vascular Barrier Function, Endothelial Survival and Homeostasis of the Adult Microvasculature

(2009) Tony E. Walshe et al.   PLoS One

The Benefit of Docosahexanoic Acid on the Migration of Vascular Smooth Muscle Cells Is Partially Dependent on Notch Regulation of MMP-2/-9

(2008) Sandrine Delbosc et al.   AMERICAN JOURNAL OF PATHOLOGY

Role of transforming growth factor-β superfamily signaling pathways in human disease

(2008) Kelly J. Gordon et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

TGF-β signaling in vascular biology and dysfunction

(2008) Marie-José Goumans et al.   CELL RESEARCH

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

(2008) Jürgen Cox et al.   NATURE BIOTECHNOLOGY