Structural basis for misregulation of kinesin KIF21A autoinhibition by CFEOM1 disease mutations
Published 2016 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Structural basis for misregulation of kinesin KIF21A autoinhibition by CFEOM1 disease mutations
Authors
Keywords
-
Journal
Scientific Reports
Volume 6, Issue 1, Pages -
Publisher
Springer Nature
Online
2016-08-03
DOI
10.1038/srep30668
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- The kinesin-4 protein Kif7 regulates mammalian Hedgehog signalling by organizing the cilium tip compartment
- (2014) Mu He et al. NATURE CELL BIOLOGY
- Human CFEOM1 Mutations Attenuate KIF21A Autoinhibition and Cause Oculomotor Axon Stalling
- (2014) Long Cheng et al. NEURON
- Microtubule Minus-End Binding Protein CAMSAP2 Controls Axon Specification and Dendrite Development
- (2014) Kah Wai Yau et al. NEURON
- Abundant kif21b is associated with accelerated progression in neurodegenerative diseases
- (2014) Karim L Kreft et al. Acta Neuropathologica Communications
- Oncogenic role of kinesin proteins and targeting kinesin therapy
- (2013) Xinran Liu et al. CANCER SCIENCE
- CFEOM1-Associated Kinesin KIF21A Is a Cortical Microtubule Growth Inhibitor
- (2013) Babet van der Vaart et al. DEVELOPMENTAL CELL
- Structure of a kinesin–tubulin complex and implications for kinesin motility
- (2013) Benoît Gigant et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- TRIM3 Regulates the Motility of the Kinesin Motor Protein KIF21B
- (2013) Dorthe Labonté et al. PLoS One
- End Binding Proteins Are Obligatory Dimers
- (2013) Indrani Sen et al. PLoS One
- AMPLE: a cluster-and-truncate approach to solve the crystal structures of small proteins using rapidly computedab initiomodels
- (2012) Jaclyn Bibby et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- High-Precision Isothermal Titration Calorimetry with Automated Peak-Shape Analysis
- (2012) Sandro Keller et al. ANALYTICAL CHEMISTRY
- New developments in theATSASprogram package for small-angle scattering data analysis
- (2012) Maxim V. Petoukhov et al. JOURNAL OF APPLIED CRYSTALLOGRAPHY
- KIF21A-Mediated Axonal Transport and Selective Endocytosis Underlie the Polarized Targeting of NCKX2
- (2012) K.-H. Lee et al. JOURNAL OF NEUROSCIENCE
- A mutation in KIF7 is responsible for the autosomal recessive syndrome of macrocephaly, multiple epiphyseal dysplasia and distinctive facial appearance
- (2012) Bassam R Ali et al. Orphanet Journal of Rare Diseases
- The CC1-FHA Tandem as a Central Hub for Controlling the Dimerization and Activation of Kinesin-3 KIF1A
- (2012) Lin Huo et al. STRUCTURE
- Structural analysis of vascular endothelial growth factor receptor-2/ligand complexes by small-angle X-ray solution scattering
- (2011) Kaisa Kisko et al. FASEB JOURNAL
- KIF21A novel deletion and recurrent mutation in patients with congenital fibrosis of the extraocular muscles-1
- (2011) Qingjiong Zhang INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- KIF7 mutations cause fetal hydrolethalus and acrocallosal syndromes
- (2011) Audrey Putoux et al. NATURE GENETICS
- Post-translational regulation of the microtubule cytoskeleton: mechanisms and functions
- (2011) Carsten Janke et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- The Structure of the Kinesin-1 Motor-Tail Complex Reveals the Mechanism of Autoinhibition
- (2011) H. Y. K. Kaan et al. SCIENCE
- XDS
- (2010) Wolfgang Kabsch ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Features and development ofCoot
- (2010) P. Emsley et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- PHENIX: a comprehensive Python-based system for macromolecular structure solution
- (2010) Paul D. Adams et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Automated seamless DNA co-transformation cloning with direct expression vectors applying positive or negative insert selection
- (2010) Natacha Olieric et al. BMC BIOTECHNOLOGY
- Linking molecular motors to membrane cargo
- (2010) Anna Akhmanova et al. CURRENT OPINION IN CELL BIOLOGY
- Autoinhibition of the kinesin-2 motor KIF17 via dual intramolecular mechanisms
- (2010) Jennetta W. Hammond et al. JOURNAL OF CELL BIOLOGY
- MolProbity: all-atom structure validation for macromolecular crystallography
- (2009) Vincent B. Chen et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- A major mutation of KIF21A associated with congenital fibrosis of the extraocular muscles type 1 (CFEOM1) enhances translocation of Kank1 to the membrane
- (2009) Naoto Kakinuma et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- DAMMIF, a program for rapidab-initioshape determination in small-angle scattering
- (2009) Daniel Franke et al. JOURNAL OF APPLIED CRYSTALLOGRAPHY
- Axonal Transport Defects in Neurodegenerative Diseases
- (2009) G. A. Morfini et al. JOURNAL OF NEUROSCIENCE
- Traffic control: regulation of kinesin motors
- (2009) Kristen J. Verhey et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Structure prediction for CASP8 with all-atom refinement using Rosetta
- (2009) Srivatsan Raman et al. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS
- Basic mechanisms for recognition and transport of synaptic cargos
- (2009) Max A Schlager et al. Molecular Brain
- Phosphorylation Relieves Autoinhibition of the Kinetochore Motor Cenp-E
- (2008) Julien Espeut et al. MOLECULAR CELL
- The kinesin-1 motor protein is regulated by a direct interaction of its head and tail
- (2008) Kristen A. Dietrich et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Interaction of brefeldin A-inhibited guanine nucleotide-exchange protein (BIG) 1 and kinesin motor protein KIF21A
- (2008) X. Shen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started