Post-Cardiac Arrest: Mechanisms, Management, and Future Perspectives

ERC-ESICM guidelines on temperature control after cardiac arrest in adults

(2022) Claudio Sandroni et al.   INTENSIVE CARE MEDICINE

Treating Rhythmic and Periodic EEG Patterns in Comatose Survivors of Cardiac Arrest

(2022) Barry J. Ruijter et al.   NEW ENGLAND JOURNAL OF MEDICINE

Targeted Temperature Management After In-Hospital Cardiac Arrest

(2022) Alexiane Blanc et al.   CHEST

Ventilatory settings in the initial 72 h and their association with outcome in out-of-hospital cardiac arrest patients: a preplanned secondary analysis of the targeted hypothermia versus targeted normothermia after out-of-hospital cardiac arrest (TTM2) trial

(2022) Chiara Robba et al.   INTENSIVE CARE MEDICINE

2022 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations: Summary From the Basic Life Support; Advanced Life Support; Pediatric Life Support; Neonatal Life Support; Education, Implementation, and Teams; and First Aid Task Forces

(2022) Myra H. Wyckoff et al.   CIRCULATION

Blood-Pressure Targets in Comatose Survivors of Cardiac Arrest

(2022) Jesper Kjaergaard et al.   NEW ENGLAND JOURNAL OF MEDICINE

Oxygen Targets in Comatose Survivors of Cardiac Arrest

(2022) Henrik Schmidt et al.   NEW ENGLAND JOURNAL OF MEDICINE

Impact of the modified SESAME ultrasound protocol implementation on patients with cardiac arrest in the emergency department

(2021) Su Yeong Pyo et al.   AMERICAN JOURNAL OF EMERGENCY MEDICINE

Association of Timing of Electrocardiogram Acquisition After Return of Spontaneous Circulation With Coronary Angiography Findings in Patients With Out-of-Hospital Cardiac Arrest

(2021) Enrico Baldi et al.   JAMA Network Open

Early Head to Pelvis Computed Tomography in Out‐of‐Hospital Circulatory Arrest Without Obvious Etiology

(2021) Kelley R.H. Branch et al.   ACADEMIC EMERGENCY MEDICINE

Diagnostic test accuracy of the initial electrocardiogram after resuscitation from cardiac arrest to indicate invasive coronary angiographic findings and attempted revascularization: A systematic review and meta-analysis

(2021) Patrick McFadden et al.   RESUSCITATION

Which Target Temperature for Post-Anoxic Brain Injury? A Systematic Review from “Real Life” Studies

(2021) Andrea Minini et al.   Brain Sciences

European Resuscitation Council and European Society of Intensive Care Medicine guidelines 2021: post-resuscitation care

(2021) Jerry P. Nolan et al.   INTENSIVE CARE MEDICINE

European Resuscitation Council Guidelines 2021: Cardiac arrest in special circumstances

(2021) Carsten Lott et al.   RESUSCITATION

Molar Sodium Lactate Attenuates the Severity of Postcardiac Arrest Syndrome

(2021) Neven Stevic et al.   CRITICAL CARE MEDICINE

Angiography after Out-of-Hospital Cardiac Arrest without ST-Segment Elevation

(2021) Steffen Desch et al.   NEW ENGLAND JOURNAL OF MEDICINE

Hypothermia versus Normothermia after Out-of-Hospital Cardiac Arrest

(2021) Josef Dankiewicz et al.   NEW ENGLAND JOURNAL OF MEDICINE

Mechanical circulatory support in post-cardiac arrest: One two many?

(2021) Saraschandra Vallabhajosyula et al.   RESUSCITATION

Brain injury after cardiac arrest: pathophysiology, treatment, and prognosis

(2021) Claudio Sandroni et al.   INTENSIVE CARE MEDICINE

Brain injury after cardiac arrest

(2021) Gavin D Perkins et al.   LANCET

Impact of Cardiac Arrest Centers on the Survival of Patients With Nontraumatic Out‐of‐Hospital Cardiac Arrest: A Systematic Review and Meta‐Analysis

(2021) Jun Wei Yeo et al.   Journal of the American Heart Association

Sudden Cardiac Arrest Survivorship: A Scientific Statement From the American Heart Association

(2020) Kelly N. Sawyer et al.   CIRCULATION

Cyclosporine A prevents cardiac arrest-induced acute respiratory failure: a post-hoc analysis of the CYRUS trial

(2020) Louis Kreitmann et al.   INTENSIVE CARE MEDICINE

Comprehensive Cardiac Care After Cardiac Arrest

(2020) Barry Burstein et al.   CRITICAL CARE CLINICS

Optimum Blood Pressure in Patients With Shock After Acute Myocardial Infarction and Cardiac Arrest

(2020) Koen Ameloot et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Etiology and Determinants of In-Hospital Survival in Patients Resuscitated After Out-of-Hospital Cardiac Arrest in an Urban Medical Center

(2020) Amir J. Khan et al.   AMERICAN JOURNAL OF CARDIOLOGY

A Randomized Pilot Clinical Trial of Early Coronary Angiography Versus No Early Coronary Angiography for Post-Cardiac Arrest Patients Without ST-Segment Elevation: The PEARL Study

(2020) Karl B. Kern et al.   CIRCULATION

Part 3: Adult Basic and Advanced Life Support: 2020 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care

(2020) Ashish R. Panchal et al.   CIRCULATION

Coronary Angiography After Cardiac Arrest Without ST Segment Elevation

(2020) Jorrit S. Lemkes et al.   JAMA Cardiology

Post-resuscitation shock: recent advances in pathophysiology and treatment

(2020) Mathieu Jozwiak et al.   Annals of Intensive Care

Reasons for death in patients successfully resuscitated from out-of-hospital and in-hospital cardiac arrest

(2019) Lise Witten et al.   RESUSCITATION

In-Hospital Cardiac Arrest

(2019) Lars W. Andersen et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

The Burden of Brain Hypoxia and Optimal Mean Arterial Pressure in Patients With Hypoxic Ischemic Brain Injury After Cardiac Arrest

(2019) Mypinder S. Sekhon et al.   CRITICAL CARE MEDICINE

Hypoxic liver injury after in- and out-of-hospital cardiac arrest: Risk factors and neurological outcome

(2019) Kevin Roedl et al.   RESUSCITATION

Hemodynamic efficiency of hemodialysis treatment with high cut-off membrane during the early period of post-resuscitation shock: The HYPERDIA trial

(2019) Guillaume Geri et al.   RESUSCITATION

Outcome after pre-hospital cardiac arrest in accordance with underlying cause

(2019) Holger Gässler et al.   RESUSCITATION

Optimal Arterial Blood Oxygen Tension in the Early Postresuscitation Phase of Extracorporeal Cardiopulmonary Resuscitation

(2019) Wei-Tien Chang et al.   CRITICAL CARE MEDICINE

Direct or subacute coronary angiography in out-of-hospital cardiac arrest (DISCO)—An initial pilot-study of a randomized clinical trial

(2019) Ludvig Elfwén et al.   RESUSCITATION

Cardiac Arrest and Cardiopulmonary Resuscitation Outcome Reports: Update of the Utstein Resuscitation Registry Template for In-Hospital Cardiac Arrest: A Consensus Report From a Task Force of the International Liaison Committee on Resuscitation (American Heart Association, European Resuscitation Council, Australian and New Zealand Council on Resuscitation, Heart and Stroke Foundation of Canada, InterAmerican Heart Foundation, Resuscitation Council of Southern Africa, Resuscitation Council of Asia)

(2019) Jerry P. Nolan et al.   CIRCULATION

Focused cardiac ultrasound after return of spontaneous circulation in cardiac-arrest patients

(2019) Ludvig Elfwén et al.   RESUSCITATION

Optimizing the Early Resuscitation After Out-of-Hospital Cardiac Arrest

(2019) Peter M. Reardon et al.   JOURNAL OF INTENSIVE CARE MEDICINE

Understanding and Improving Critical Care Survivorship

(2019) Aluko A. Hope et al.   AMERICAN JOURNAL OF CRITICAL CARE

Long-term survival in out-of-hospital cardiac arrest patients treated with targeted temperature control at 33 °C or 36 °C: A national registry study

(2019) Lis Abazi et al.   RESUSCITATION

Targeted Temperature Management for Cardiac Arrest with Nonshockable Rhythm

(2019) Jean-Baptiste Lascarrou et al.   NEW ENGLAND JOURNAL OF MEDICINE

The Cardiac Arrest Sonographic Assessment (CASA) exam – A standardized approach to the use of ultrasound in PEA

(2018) Kevin F. Gardner et al.   AMERICAN JOURNAL OF EMERGENCY MEDICINE

Randomized controlled trial of internal and external targeted temperature management methods in post- cardiac arrest patients

(2018) Xinqi Look et al.   AMERICAN JOURNAL OF EMERGENCY MEDICINE

Does Early Coronary Angiography Improve Survival After out-of-Hospital Cardiac Arrest? A Systematic Review With Meta-Analysis

(2018) Michelle Welsford et al.   CANADIAN JOURNAL OF CARDIOLOGY

Multidisciplinary Management of the Post–Cardiac Arrest Patient

(2018) Ryan D. Madder et al.   CARDIOLOGY CLINICS

Critical Care of the Post–Cardiac Arrest Patient

(2018) Amy C. Walker et al.   CARDIOLOGY CLINICS

Return to Work and Participation in Society After Out-of-Hospital Cardiac Arrest

(2018) Gisela Lilja et al.  

Posttraumatic stress and depressive symptoms characterize cardiac arrest survivors' perceived recovery at hospital discharge

(2018) Alex Presciutti et al.   GENERAL HOSPITAL PSYCHIATRY

Time to awakening after cardiac arrest and the association with target temperature management

(2018) Anna Lybeck et al.   RESUSCITATION

Arrest etiology among patients resuscitated from cardiac arrest

(2018) Niel Chen et al.   RESUSCITATION

Return to Work and Participation in Society After Out-of-Hospital Cardiac Arrest

(2018) Gisela Lilja et al.   Circulation-Cardiovascular Quality and Outcomes

Severe metabolic acidosis after out-of-hospital cardiac arrest: risk factors and association with outcome

(2018) Matthieu Jamme et al.   Annals of Intensive Care

Changes in Temperature Management of Cardiac Arrest Patients Following Publication of the Target Temperature Management Trial

(2018) Ryan Salter et al.   CRITICAL CARE MEDICINE

Diagnostic Yield of Non-Invasive Imaging in Patients Following Non-Traumatic Out-of-Hospital Sudden Cardiac Arrest: A Systematic Review

(2018) Bradley J. Petek et al.   RESUSCITATION

Implementation of the Cardiac Arrest Sonographic Assessment (CASA) protocol for patients with cardiac arrest is associated with shorter CPR pulse checks

(2018) Eben J. Clattenburg et al.   RESUSCITATION

Association Between Elevated Mean Arterial Blood Pressure and Neurologic Outcome After Resuscitation From Cardiac Arrest

(2018) Brian W. Roberts et al.   CRITICAL CARE MEDICINE

Targeting low-normal or high-normal mean arterial pressure after cardiac arrest and resuscitation: a randomised pilot trial

(2018) Pekka Jakkula et al.   INTENSIVE CARE MEDICINE

The Role of Inflammatory Cytokines in Cardiac Arrest

(2018) Christopher Jou et al.   JOURNAL OF INTENSIVE CARE MEDICINE

Targeted Temperature Management for 48 vs 24 Hours and Neurologic Outcome After Out-of-Hospital Cardiac Arrest

(2017) Hans Kirkegaard et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Oxidative stress and abnormal cholesterol metabolism in patients with post-cardiac arrest syndrome

(2017) Midori Nagase et al.   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

Coronary Artery Disease in Patients With Out-of-Hospital Refractory Ventricular Fibrillation Cardiac Arrest

(2017) Demetris Yannopoulos et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Etiological diagnoses of out-of-hospital cardiac arrest survivors admitted to the intensive care unit: Insights from a French registry

(2017) Guillaume Geri et al.   RESUSCITATION

Cognitive impairments and subjective cognitive complaints after survival of cardiac arrest: A prospective longitudinal cohort study

(2017) Catherine V.M. Steinbusch et al.   RESUSCITATION

Impact of mean arterial pressure on clinical outcomes in comatose survivors of out-of-hospital cardiac arrest: Insights from the University of Ottawa Heart Institute Regional Cardiac Arrest Registry (CAPITAL-CARe)

(2017) Juan J. Russo et al.   RESUSCITATION

Changing target temperature from 33 °C to 36 °C in the ICU management of out-of-hospital cardiac arrest: A before and after study

(2017) Janet E. Bray et al.   RESUSCITATION

Derivation and Validation of the CREST Model for Very Early Prediction of Circulatory Etiology Death in Patients Without ST-Segment–Elevation Myocardial Infarction After Cardiac Arrest

(2017) Karen E. Bascom et al.   CIRCULATION

Response to Letter Regarding Article, “Endovascular Versus External Targeted Temperature Management for Patients With Out-of-Hospital Cardiac Arrest: A Randomized, Controlled Study”

(2016) Nicolas Deye et al.   CIRCULATION

Comparison of health-related quality of life and functional recovery measurement tools in out-of-hospital cardiac arrest survivors

(2016) Emily Andrew et al.   RESUSCITATION

Hypoxic hepatitis after out-of-hospital cardiac arrest: Incidence, determinants and prognosis

(2016) B. Champigneulle et al.   RESUSCITATION

Early antibiotics administration during targeted temperature management after out-of-hospital cardiac arrest: a nationwide database study

(2016) Takashi Tagami et al.   BMC Anesthesiology

Location of In‐Hospital Cardiac Arrest in the United States—Variability in Event Rate and Outcomes

(2016) Sarah M. Perman et al.   Journal of the American Heart Association

Effect of Cyclosporine in Nonshockable Out-of-Hospital Cardiac Arrest

(2016) Laurent Argaud et al.   JAMA Cardiology

An overview of microRNAs

(2015) Scott M. Hammond   ADVANCED DRUG DELIVERY REVIEWS

Hypoxic hepatitis in survivors of out-of-hospital cardiac arrest

(2015) Sang Hoon Oh et al.   AMERICAN JOURNAL OF EMERGENCY MEDICINE

Stress-Induced Cardiomyopathy

(2015) Torrey A. Boland et al.   CRITICAL CARE MEDICINE

Hemodynamics and Vasopressor Support During Targeted Temperature Management at 33°C Versus 36°C After Out-of-Hospital Cardiac Arrest

(2015) John Bro-Jeppesen et al.   CRITICAL CARE MEDICINE

European Resuscitation Council and European Society of Intensive Care Medicine 2015 guidelines for post-resuscitation care

(2015) Jerry P. Nolan et al.   INTENSIVE CARE MEDICINE

Outcomes of Comatose Cardiac Arrest Survivors With and Without ST-Segment Elevation Myocardial Infarction

(2015) Karl B. Kern et al.   JACC-Cardiovascular Interventions

Prophylactic antibiotics are associated with a lower incidence of pneumonia in cardiac arrest survivors treated with targeted temperature management

(2015) David J. Gagnon et al.   RESUSCITATION

Recognizing the causes of in-hospital cardiac arrest — A survival benefit

(2015) Daniel Bergum et al.   RESUSCITATION

Hemodynamic targets during therapeutic hypothermia after cardiac arrest: A prospective observational study

(2015) K. Ameloot et al.   RESUSCITATION

Recent Trends in Survival From Out-of-Hospital Cardiac Arrest in the United States

(2014) Paul S. Chan et al.   CIRCULATION

Die another way – non-apoptotic mechanisms of cell death

(2014) Stephen W. G. Tait et al.   JOURNAL OF CELL SCIENCE

Myocardial depression in sepsis: From pathogenesis to clinical manifestations and treatment

(2014) Elio Antonucci et al.   JOURNAL OF CRITICAL CARE

Post-resuscitation electrocardiograms, acute coronary findings and in-hospital prognosis of survivors of out-of-hospital cardiac arrest

(2014) Julio Garcia-Tejada et al.   RESUSCITATION

Cardiac catheterization is associated with superior outcomes for survivors of out of hospital cardiac arrest: Review and meta-analysis

(2014) Anthony C. Camuglia et al.   RESUSCITATION

Invasive coronary treatment strategies for out-of-hospital cardiac arrest: a consensus statement from the European Association for Percutaneous Cardiovascular Interventions (EAPCI)/Stent for Life (SFL) groups

(2014) Marko Noc et al.   EuroIntervention

Association Between Postresuscitation Partial Pressure of Arterial Carbon Dioxide and Neurological Outcome in Patients With Post–Cardiac Arrest Syndrome

(2013) Brian W. Roberts et al.   CIRCULATION

Cardiovascular Health: The Importance of Measuring Patient-Reported Health Status

(2013) John S. Rumsfeld et al.   CIRCULATION

Intensive care unit mortality after cardiac arrest: the relative contribution of shock and brain injury in a large cohort

(2013) Virginie Lemiale et al.   INTENSIVE CARE MEDICINE

Temperature Management and Modern Post–Cardiac Arrest Care

(2013) Jon C. Rittenberger et al.   NEW ENGLAND JOURNAL OF MEDICINE

Targeted Temperature Management at 33°C versus 36°C after Cardiac Arrest

(2013) Niklas Nielsen et al.   NEW ENGLAND JOURNAL OF MEDICINE

Predictive value of electrocardiogram in diagnosing acute coronary artery lesions among patients with out-of-hospital-cardiac-arrest

(2013) Davide Zanuttini et al.   RESUSCITATION

Cardioprotection during cardiac surgery

(2012) D. J. Hausenloy et al.   CARDIOVASCULAR RESEARCH

Reactive oxygen species (ROS) homeostasis and redox regulation in cellular signaling

(2012) Paul D. Ray et al.   CELLULAR SIGNALLING

Guidelines for the use of an insulin infusion for the management of hyperglycemia in critically ill patients

(2012) Judith Jacobi et al.   CRITICAL CARE MEDICINE

Trends in Survival after In-Hospital Cardiac Arrest

(2012) Saket Girotra et al.   NEW ENGLAND JOURNAL OF MEDICINE

Causes of in-hospital cardiac arrest and influence on outcome

(2012) Christian Wallmuller et al.   RESUSCITATION

Early-Onset Pneumonia after Cardiac Arrest

(2011) Sébastien Perbet et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

‘Stand still … , and move on’, a new early intervention service for cardiac arrest survivors and their caregivers: rationale and description of the intervention

(2011) Véronique RMP Moulaert et al.   CLINICAL REHABILITATION

Infectious complications in out-of-hospital cardiac arrest patients in the therapeutic hypothermia era*

(2011) Nicolas Mongardon et al.   CRITICAL CARE MEDICINE

Postresuscitation syndrome: Potential role of hydroxyl radical-induced endothelial cell damage*

(2011) Olivier Huet et al.   CRITICAL CARE MEDICINE

Pathophysiology and pathogenesis of post-resuscitation myocardial stunning

(2011) Athanasios Chalkias et al.   HEART FAILURE REVIEWS

Ischemia and reperfusion—from mechanism to translation

(2011) Holger K Eltzschig et al.   NATURE MEDICINE

Does appropriate treatment of the primary underlying cause of PEA during resuscitation improve patients’ survival?

(2011) Sini Saarinen et al.   RESUSCITATION

Postcardiac arrest syndrome: from immediate resuscitation to long-term outcome

(2011) Nicolas Mongardon et al.   Annals of Intensive Care

The effects of mild induced hypothermia on the myocardium: a systematic review

(2010) F. E. Kelly et al.   ANAESTHESIA

Extracellular Adenosine: A Safety Signal That Dampens Hypoxia-Induced Inflammation During Ischemia

(2010) Almut Grenz et al.   ANTIOXIDANTS & REDOX SIGNALING

Calcium-Mediated Mechanisms of Ischemic Injury and Protection

(2010) Paul Morley et al.   BRAIN PATHOLOGY

A comparison of intravascular and surface cooling techniques in comatose cardiac arrest survivors*

(2010) Øystein Tømte et al.   CRITICAL CARE MEDICINE

Complement: a key system for immune surveillance and homeostasis

(2010) Daniel Ricklin et al.   NATURE IMMUNOLOGY

Myocardial Fatty Acid Metabolism in Health and Disease

(2010) Gary D. Lopaschuk et al.   PHYSIOLOGICAL REVIEWS

European Resuscitation Council Guidelines for Resuscitation 2010 Section 1. Executive summary

(2010) Jerry P. Nolan et al.   RESUSCITATION

Pivotal role of cerebral interleukin-17–producing γδT cells in the delayed phase of ischemic brain injury

(2009) Takashi Shichita et al.   NATURE MEDICINE

Cell Death

(2009) Richard S. Hotchkiss et al.   NEW ENGLAND JOURNAL OF MEDICINE

Life after survival: Long-term daily functioning and quality of life after an out-of-hospital cardiac arrest

(2009) E.M. Wachelder et al.   RESUSCITATION

No difference in autopsy detected injuries in cardiac arrest patients treated with manual chest compressions compared with mechanical compressions with the LUCAS™ device—A pilot study

(2009) David Smekal et al.   RESUSCITATION

Identification of Splenic Reservoir Monocytes and Their Deployment to Inflammatory Sites

(2009) F. K. Swirski et al.   SCIENCE

Acute coronary angiographic findings in survivors of out-of-hospital cardiac arrest

(2008) Zacharias Alexandros Anyfantakis et al.   AMERICAN HEART JOURNAL

HIF-1-dependent repression of adenosine kinase attenuates hypoxia-induced vascular leak

(2008) J. C. Morote-Garcia et al.   BLOOD

Post-cardiac arrest syndrome: Epidemiology, pathophysiology, treatment, and prognostication

(2008) Jerry P. Nolan et al.   RESUSCITATION