Myocardial Fatty Acid Metabolism in Health and Disease

Targeting malonyl CoA inhibition of mitochondrial fatty acid uptake as an approach to treat cardiac ischemia/reperfusion

(2009) John R. Ussher et al.   BASIC RESEARCH IN CARDIOLOGY

Metabolomic Profiling Reveals Distinct Patterns of Myocardial Substrate Use in Humans With Coronary Artery Disease or Left Ventricular Dysfunction During Surgical Ischemia/Reperfusion

(2009) Aslan T. Turer et al.   CIRCULATION

Metabolic MRI of myocardial and hepatic triglyceride content in response to nutritional interventions

(2009) Hildo J Lamb et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Insulin-Stimulated Cardiac Glucose Oxidation Is Increased in High-Fat Diet-Induced Obese Mice Lacking Malonyl CoA Decarboxylase

(2009) J. R. Ussher et al.   DIABETES

Tight Glycemic Control Reduces Heart Inflammation and Remodeling During Acute Myocardial Infarction in Hyperglycemic Patients

(2009) Raffaele Marfella et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Cellular fatty acid uptake: a pathway under construction

(2009) Xiong Su et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Short-term flexibility of myocardial triglycerides and diastolic function in patients with type 2 diabetes mellitus

(2008) Sebastiaan Hammer et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Reverse changes in cardiac substrate oxidation in dogs recovering from heart failure

(2008) Khaled Qanud et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Ranolazine combined with enalapril or metoprolol prevents progressive LV dysfunction and remodeling in dogs with moderate heart failure

(2008) Sharad Rastogi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Reduced heart size and increased myocardial fuel substrate oxidation in ACC2 mutant mice

(2008) M. Faadiel Essop et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

The transcriptional coactivator PGC-1α is essential for maximal and efficient cardiac mitochondrial fatty acid oxidation and lipid homeostasis

(2008) John J. Lehman et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Metabolic (In)Flexibility of the Diabetic Heart

(2008) Terje S. Larsen et al.   CARDIOVASCULAR DRUGS AND THERAPY

Role of diet and fuel overabundance in the development and progression of heart failure

(2008) D. J. Chess et al.   CARDIOVASCULAR RESEARCH

Lack of functional assembly in mitochondrial supercomplexes: a new insight into impaired mitochondrial function?

(2008) F. J. Garcia-Palmer   CARDIOVASCULAR RESEARCH

The malonyl CoA axis as a potential target for treating ischaemic heart disease

(2008) J. R. Ussher et al.   CARDIOVASCULAR RESEARCH

Regulation of sarcolemmal glucose and fatty acid transporters in cardiac disease

(2008) R. W. Schwenk et al.   CARDIOVASCULAR RESEARCH

Adiponectin protects against myocardial ischaemia-reperfusion injury via AMP-activated protein kinase, Akt, and nitric oxide

(2008) A. T. Gonon et al.   CARDIOVASCULAR RESEARCH

Cardiac mitochondria in heart failure: decrease in respirasomes and oxidative phosphorylation

(2008) Mariana G. Rosca et al.   CARDIOVASCULAR RESEARCH

Trimetazidine, a Metabolic Modulator, Has Cardiac and Extracardiac Benefits in Idiopathic Dilated Cardiomyopathy

(2008) Helena Tuunanen et al.   CIRCULATION

Obesity and Free Fatty Acids

(2008) Guenther Boden   ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA

Opposite Regulation of CD36 Ubiquitination by Fatty Acids and Insulin

(2008) Jill Smith et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Effects of a High Saturated Fat Diet on Cardiac Hypertrophy and Dysfunction in Response to Pressure Overload

(2008) David J. Chess et al.   JOURNAL OF CARDIAC FAILURE

Differential impact of adipokines derived from primary adipocytes of wild-type versus streptozotocin-induced diabetic rats on glucose and fatty acid metabolism in cardiomyocytes

(2008) Rengasamy Palanivel et al.   JOURNAL OF ENDOCRINOLOGY

Regulation of fatty acid uptake into tissues: lipoprotein lipase- and CD36-mediated pathways: Fig. 1.

(2008) Ira J. Goldberg et al.   JOURNAL OF LIPID RESEARCH

Ceramide is a cardiotoxin in lipotoxic cardiomyopathy

(2008) Tae-Sik Park et al.   JOURNAL OF LIPID RESEARCH

Ranolazine improves diastolic dysfunction in isolated myocardium from failing human hearts — Role of late sodium current and intracellular ion accumulation

(2008) Samuel Sossalla et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

The PPAR trio: Regulators of myocardial energy metabolism in health and disease

(2008) Jose A. Madrazo et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

PGC-1α and ERRα target gene downregulation is a signature of the failing human heart

(2008) Smita Sihag et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Prolonged Caloric Restriction in Obese Patients With Type 2 Diabetes Mellitus Decreases Myocardial Triglyceride Content and Improves Myocardial Function

(2008) Sebastiaan Hammer et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Molecular and metabolic mechanisms of insulin resistance and β-cell failure in type 2 diabetes

(2008) Deborah M. Muoio et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Cardiac Remodeling in Obesity

(2008) E. Dale Abel et al.   PHYSIOLOGICAL REVIEWS

Metabolic response to an acute jump in cardiac workload: effects on malonyl-CoA, mechanical efficiency, and fatty acid oxidation

(2007) Lufang Zhou et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Progressive Caloric Restriction Induces Dose-Dependent Changes in Myocardial Triglyceride Content and Diastolic Function in Healthy Men

(2007) Sebastiaan Hammer et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Fenofibrate modulates cardiac and hepatic metabolism and increases ischemic tolerance in diet-induced obese mice

(2007) Ellen Aasum et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY