Lactate promotes endothelial-to-mesenchymal transition via Snail1 lactylation after myocardial infarction
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Title
Lactate promotes endothelial-to-mesenchymal transition via Snail1 lactylation after myocardial infarction
Authors
Keywords
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Journal
Science Advances
Volume 9, Issue 5, Pages -
Publisher
American Association for the Advancement of Science (AAAS)
Online
2023-02-04
DOI
10.1126/sciadv.adc9465
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Note: Only part of the references are listed.- Cardiovascular Dysfunction in COVID-19: Association Between Endothelial Cell Injury and Lactate
- (2022) Kun Yang et al. Frontiers in Immunology
- Lactate induces vascular permeability via disruption of VE-cadherin in endothelial cells during sepsis
- (2022) Kun Yang et al. Science Advances
- Heart Disease and Stroke Statistics—2021 Update: A Report From the American Heart Association
- (2021) Salim S. Virani et al. CIRCULATION
- Single cell sequencing reveals endothelial plasticity with transient mesenchymal activation after myocardial infarction
- (2021) Lukas S. Tombor et al. Nature Communications
- Lactate promotes macrophage HMGB1 lactylation, acetylation, and exosomal release in polymicrobial sepsis
- (2021) Kun Yang et al. CELL DEATH AND DIFFERENTIATION
- Protein lactylation induced by neural excitation
- (2021) Hideo Hagihara et al. Cell Reports
- Endothelial-specific Loss of IFT88 Promotes Endothelial-to-Mesenchymal Transition and Exacerbates Bleomycin-induced Pulmonary Fibrosis
- (2020) Shweta Singh et al. Scientific Reports
- A potent CBP/p300-Snail interaction inhibitor suppresses tumor growth and metastasis in wild-type p53-expressing cancer
- (2020) Hong-Mei Li et al. Science Advances
- Lactate Increases Renal Cell Carcinoma Aggressiveness through Sirtuin 1-Dependent Epithelial Mesenchymal Transition Axis Regulation
- (2020) Vera Miranda-Gonçalves et al. Cells
- Lactate released by inflammatory bone marrow neutrophils induces their mobilization via endothelial GPR81 signaling
- (2020) Eman Khatib-Massalha et al. Nature Communications
- Endothelial cell HSPA12B and yes-associated protein cooperatively regulate angiogenesis following myocardial infarction
- (2020) Min Fan et al. JCI Insight
- Lactate Dehydrogenase A Governs Cardiac Hypertrophic Growth in Response to Hemodynamic Stress
- (2020) Chongshan Dai et al. Cell Reports
- Lactate Suppresses Macrophage Pro-Inflammatory Response to LPS Stimulation by Inhibition of YAP and NF-κB Activation via GPR81-Mediated Signaling
- (2020) Kun Yang et al. Frontiers in Immunology
- Endothelial to Mesenchymal Transition in Cardiovascular Disease
- (2019) Jason C. Kovacic et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- A simple protocol for isolating mouse lung endothelial cells
- (2019) Jinping Wang et al. Scientific Reports
- Endothelial-to-Mesenchymal Transition
- (2019) Joyce Bischoff CIRCULATION RESEARCH
- Single-cell transcriptome analyses reveal novel targets modulating cardiac neovascularization by resident endothelial cells following myocardial infarction
- (2019) Ziwen Li et al. EUROPEAN HEART JOURNAL
- Calcitriol Attenuates Doxorubicin-Induced Cardiac Dysfunction and Inhibits Endothelial-to-Mesenchymal Transition in Mice
- (2019) Tsai et al. Cells
- Metabolic regulation of gene expression by histone lactylation
- (2019) Di Zhang et al. NATURE
- Endothelial–mesenchymal transition in atherosclerosis
- (2018) Celine Souilhol et al. CARDIOVASCULAR RESEARCH
- The Science and Translation of Lactate Shuttle Theory
- (2018) George A. Brooks Cell Metabolism
- Clonal Expansion of Endothelial Cells Contributes to Ischemia-Induced NeovascularizationNovelty and Significance
- (2018) Yosif Manavski et al. CIRCULATION RESEARCH
- Increased blood lactate is prevalent and identifies poor prognosis in patients with acute heart failure without overt peripheral hypoperfusion
- (2018) Robert Zymliński et al. EUROPEAN JOURNAL OF HEART FAILURE
- Reassessing endothelial-to-mesenchymal transition in cardiovascular diseases
- (2018) Yan Li et al. Nature Reviews Cardiology
- Epigenetic Regulation of Endothelial-to-Mesenchymal Transition in Chronic Heart Disease
- (2018) Melanie S. Hulshoff et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Lactate transporters as therapeutic targets in cancer and inflammatory diseases
- (2018) Valentina Pucino et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- Clinical, respiratory, haemodynamic, and metabolic determinants of lactate in heart failure
- (2018) Jan Biegus et al. Kardiologia Polska
- Dual Inhibition of the Lactate Transporters MCT1 and MCT4 Is Synthetic Lethal with Metformin due to NAD+ Depletion in Cancer Cells
- (2018) Don Benjamin et al. Cell Reports
- TGF-β-Induced Endothelial-Mesenchymal Transition in Fibrotic Diseases
- (2017) Evangelia Pardali et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Fibroblast-specific TGF-β–Smad2/3 signaling underlies cardiac fibrosis
- (2017) Hadi Khalil et al. JOURNAL OF CLINICAL INVESTIGATION
- Enhanced Glycolytic Metabolism Contributes to Cardiac Dysfunction in Polymicrobial Sepsis
- (2017) Zhibo Zheng et al. JOURNAL OF INFECTIOUS DISEASES
- LDHA promotes tumor metastasis by facilitating epithelial-mesenchymal transition in renal cell carcinoma
- (2017) Juping Zhao et al. Molecular Medicine Reports
- TGF-β Signaling in Control of Cardiovascular Function
- (2017) Marie-José Goumans et al. Cold Spring Harbor Perspectives in Biology
- Shear stress induces endothelial-to-mesenchymal transition via the transcription factor Snail
- (2017) Marwa M. Mahmoud et al. Scientific Reports
- The TIR/BB-loop mimetic AS-1 attenuates mechanical stress-induced cardiac fibroblast activation and paracrine secretion via modulation of large tumor suppressor kinase 1
- (2016) Min Fan et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Cardiac Fibrosis
- (2016) Joshua G. Travers et al. CIRCULATION RESEARCH
- Getting to the Heart of the Matter
- (2015) Andrew Leask CIRCULATION RESEARCH
- Attenuation of cardiac dysfunction and remodeling of myocardial infarction by microRNA-130a are mediated by suppression of PTEN and activation of PI3K dependent signaling
- (2015) Chen Lu et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Pellino1-mediated TGF-β1 synthesis contributes to mechanical stress induced cardiac fibroblast activation
- (2015) Juan Song et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Tissue-based map of the human proteome
- (2015) M. Uhlen et al. SCIENCE
- Acetylation of Snail Modulates the Cytokinome of Cancer Cells to Enhance the Recruitment of Macrophages
- (2014) Dennis Shin-Shian Hsu et al. CANCER CELL
- Exosomes and Cardiac Repair After Myocardial Infarction
- (2014) Susmita Sahoo et al. CIRCULATION RESEARCH
- Fibrosis: ultimate and proximate causes
- (2014) Victor J. Thannickal et al. JOURNAL OF CLINICAL INVESTIGATION
- Resident fibroblast lineages mediate pressure overload–induced cardiac fibrosis
- (2014) Thomas Moore-Morris et al. JOURNAL OF CLINICAL INVESTIGATION
- Snail and Slug, key regulators of TGF-β-induced EMT, are sufficient for the induction of single-cell invasion
- (2013) Hildegonda P.H. Naber et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Toll-like receptor 3 plays a role in myocardial infarction and ischemia/reperfusion injury
- (2013) Chen Lu et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- The SLC16 gene family – Structure, role and regulation in health and disease
- (2013) Andrew P. Halestrap MOLECULAR ASPECTS OF MEDICINE
- Lactic Acid Is Elevated in Idiopathic Pulmonary Fibrosis and Induces Myofibroblast Differentiation via pH-Dependent Activation of Transforming Growth Factor-β
- (2012) Robert Matthew Kottmann et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Increased expression of microRNA-146a decreases myocardial ischaemia/reperfusion injury
- (2012) Xiaohui Wang et al. CARDIOVASCULAR RESEARCH
- Fibrosis and heart failure
- (2012) Ana Maria Segura et al. HEART FAILURE REVIEWS
- Transforming growth factor-β2 promotes Snail-mediated endothelial–mesenchymal transition through convergence of Smad-dependent and Smad-independent signalling
- (2011) Damian Medici et al. BIOCHEMICAL JOURNAL
- Lactate: A Metabolic Key Player in Cancer
- (2011) F. Hirschhaeuser et al. CANCER RESEARCH
- TLR2 ligands attenuate cardiac dysfunction in polymicrobial sepsis via a phosphoinositide 3-kinase-dependent mechanism
- (2010) Tuanzhu Ha et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- ERβ Impedes Prostate Cancer EMT by Destabilizing HIF-1α and Inhibiting VEGF-Mediated Snail Nuclear Localization: Implications for Gleason Grading
- (2010) Paul Mak et al. CANCER CELL
- TLR2 ligands induce cardioprotection against ischaemia/reperfusion injury through a PI3K/Akt-dependent mechanism
- (2010) T. Ha et al. CARDIOVASCULAR RESEARCH
- Endothelial Cell–Derived Endothelin-1 Promotes Cardiac Fibrosis in Diabetic Hearts Through Stimulation of Endothelial-to-Mesenchymal Transition
- (2010) Bambang Widyantoro et al. CIRCULATION
- Transforming Growth Factor β–Induced Endothelial-to-Mesenchymal Transition: A Switch to Cardiac Fibrosis?
- (2009) Marie-José Goumans et al. TRENDS IN CARDIOVASCULAR MEDICINE
- Snail is required for TGF -induced endothelial-mesenchymal transition of embryonic stem cell-derived endothelial cells
- (2008) T. Kokudo et al. JOURNAL OF CELL SCIENCE
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