Strategy of Patient-Specific Therapeutics in Cardiovascular Disease Through Single-Cell RNA Sequencing

Single-cell transcriptomics provides insights into hypertrophic cardiomyopathy

(2022) Martijn Wehrens et al.   Cell Reports

Pathogenic variants damage cell composition and single cell transcription in cardiomyopathies

(2022) Daniel Reichart et al.   SCIENCE

Donor Macrophages Modulate Rejection After Heart Transplantation

(2022) Benjamin J. Kopecky et al.   CIRCULATION

Single-cell transcriptomics trajectory and molecular convergence of clinically relevant mutations in Brugada syndrome

(2021) Richa Tambi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Single cell RNA sequencing approaches to cardiac development and congenital heart disease

(2021) Tahmina Samad et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

MiR-590-5p inhibits pathological hypertrophy mediated heart failure by targeting RTN4

(2021) Ping Fan et al.   JOURNAL OF MOLECULAR HISTOLOGY

Single-cell transcriptomic identified HIF1A as a target for attenuating acute rejection after heart transplantation

(2021) Yuan Chang et al.   BASIC RESEARCH IN CARDIOLOGY

Intratumor Heterogeneity: The Rosetta Stone of Therapy Resistance

(2020) Andriy Marusyk et al.   CANCER CELL

Transcriptional and Cellular Diversity of the Human Heart

(2020) Nathan R. Tucker et al.   CIRCULATION

Single-Cell Reconstruction of Progression Trajectory Reveals Intervention Principles in Pathological Cardiac Hypertrophy

(2020) Zongna Ren et al.   CIRCULATION

How personalised medicine will transform healthcare by 2030: the ICPerMed vision

(2020) Astrid M. Vicente et al.   Journal of Translational Medicine

Single-cell RNA sequencing in cardiovascular development, disease and medicine

(2020) David T. Paik et al.   Nature Reviews Cardiology

Single-cell RNA Sequencing: In-depth Decoding of Heart Biology and Cardiovascular Diseases

(2020) Zhongli Chen et al.   CURRENT GENOMICS

Cells of the adult human heart

(2020) Monika Litviňuková et al.   NATURE

Single-Cell Transcriptome Analysis Maps the Developmental Track of the Human Heart

(2019) Yueli Cui et al.   Cell Reports

In Vivo Generation of Post-infarct Human Cardiac Muscle by Laminin-Promoted Cardiovascular Progenitors

(2019) Lynn Yap et al.   Cell Reports

Maturation of heart valve cell populations during postnatal remodeling

(2019) Alexia Hulin et al.   DEVELOPMENT

Single-cell expression profiling reveals dynamic flux of cardiac stromal, vascular and immune cells in health and injury

(2019) Nona Farbehi et al.   eLife

Single-Cell RNA-Seq of the Developing Cardiac Outflow Tract Reveals Convergent Development of the Vascular Smooth Muscle Cells

(2019) Xuanyu Liu et al.   Cell Reports

Single-Cell Transcriptomics Reveals Chemotaxis-Mediated Intraorgan Crosstalk During Cardiogenesis

(2019) Haiqing Xiong et al.   CIRCULATION RESEARCH

The human body at cellular resolution: the NIH Human Biomolecular Atlas Program

(2019)   NATURE

Single-Cell Sequencing of the Healthy and Diseased Heart Reveals Cytoskeleton-Associated Protein 4 as a New Modulator of Fibroblasts Activation

(2018) Monika M. Gladka et al.   CIRCULATION

Emerging Role of Precision Medicine in Cardiovascular Disease

(2018) Jane A. Leopold et al.   CIRCULATION RESEARCH

Single-Cell Transcriptomics of a Human Kidney Allograft Biopsy Specimen Defines a Diverse Inflammatory Response

(2018) Haojia Wu et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The human heart contains distinct macrophage subsets with divergent origins and functions

(2018) Geetika Bajpai et al.   NATURE MEDICINE

Single-cell RNA sequencing for the study of development, physiology and disease

(2018) S. Steven Potter   Nature Reviews Nephrology

Defining the earliest step of cardiovascular lineage segregation by single-cell RNA-seq

(2018) Fabienne Lescroart et al.   SCIENCE

Single-Cell Transcriptional Profiling Reveals Cellular Diversity and Intercommunication in the Mouse Heart

(2018) Daniel A. Skelly et al.   Cell Reports

Single-Cell Transcriptomic Analysis of Cardiac Differentiation from Human PSCs Reveals HOPX-Dependent Cardiomyocyte Maturation

(2018) Clayton E. Friedman et al.   Cell Stem Cell

Defining human cardiac transcription factor hierarchies using integrated single-cell heterogeneity analysis

(2018) Jared M. Churko et al.   Nature Communications

Single-Cell Resolution of Temporal Gene Expression during Heart Development

(2016) Daniel M. DeLaughter et al.   DEVELOPMENTAL CELL

Transcriptomic Profiling Maps Anatomically Patterned Subpopulations among Single Embryonic Cardiac Cells

(2016) Guang Li et al.   DEVELOPMENTAL CELL

Towards precision medicine

(2016) Euan A. Ashley   NATURE REVIEWS GENETICS

A draft network of ligand–receptor-mediated multicellular signalling in human

(2015) Jordan A. Ramilowski et al.   Nature Communications

Full-length RNA-seq from single cells using Smart-seq2

(2014) Simone Picelli et al.   Nature Protocols

Endoplasmic Reticulum Stress Induces Different Molecular Structural Alterations in Human Dilated and Ischemic Cardiomyopathy

(2014) Ana Ortega et al.   PLoS One

Distinct macrophage lineages contribute to disparate patterns of cardiac recovery and remodeling in the neonatal and adult heart

(2014) Kory J. Lavine et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Single-Cell RNA-Seq Reveals Dynamic, Random Monoallelic Gene Expression in Mammalian Cells

(2014) Q. Deng et al.   SCIENCE

Quantitative single-cell RNA-seq with unique molecular identifiers

(2013) Saiful Islam et al.   NATURE METHODS

Sarcomere Gene Mutations Are Associated With Increased Cardiovascular Events in Left Ventricular Hypertrophy

(2013) Takashi Fujita et al.   JACC-Heart Failure