Single-Cell Reconstruction of Progression Trajectory Reveals Intervention Principles in Pathological Cardiac Hypertrophy

Single-cell reconstruction of the adult human heart during heart failure and recovery reveals the cellular landscape underlying cardiac function

(2020) Li Wang et al.   NATURE CELL BIOLOGY

Effect of Dapagliflozin on Heart Failure and Mortality in Type 2 Diabetes Mellitus

(2019) Eri T. Kato et al.   CIRCULATION

Single-cell reconstruction of differentiation trajectory reveals a critical role of ETS1 in human cardiac lineage commitment

(2019) Hang Ruan et al.   BMC BIOLOGY

Histone Variant H2A.Z is Required for the Maintenance of Smooth Muscle Cell Identity as Revealed by Single-Cell Transcriptomics

(2018) Fang Yao et al.   CIRCULATION

Single-Cell Sequencing of the Healthy and Diseased Heart Reveals Cytoskeleton-Associated Protein 4 as a New Modulator of Fibroblasts Activation

(2018) Monika M. Gladka et al.   CIRCULATION

Cardiovascular Effects of New Oral Glucose-Lowering Agents

(2018) André J. Scheen   CIRCULATION RESEARCH

Large-Scale Single-Cell RNA-Seq Reveals Molecular Signatures of Heterogeneous Populations of Human Induced Pluripotent Stem Cell-Derived Endothelial Cells

(2018) David T Paik et al.   CIRCULATION RESEARCH

Hippo Signaling Plays an Essential Role in Cell State Transitions during Cardiac Fibroblast Development

(2018) Yang Xiao et al.   DEVELOPMENTAL CELL

The human heart contains distinct macrophage subsets with divergent origins and functions

(2018) Geetika Bajpai et al.   NATURE MEDICINE

Mechanisms of physiological and pathological cardiac hypertrophy

(2018) Michinari Nakamura et al.   Nature Reviews Cardiology

Single-Cell Transcriptional Profiling Reveals Cellular Diversity and Intercommunication in the Mouse Heart

(2018) Daniel A. Skelly et al.   Cell Reports

Single-nucleus transcriptomic survey of cell diversity and functional maturation in postnatal mammalian hearts

(2018) Peng Hu et al.   GENES & DEVELOPMENT

Deficiency of GATA3-Positive Macrophages Improves Cardiac Function Following Myocardial Infarction or Pressure Overload Hypertrophy

(2018) Mingjie Yang et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Single-Cell Sequencing of the Mammalian Heart

(2018) Bas Molenaar et al.   CIRCULATION RESEARCH

Single-cell reconstruction of the early maternal–fetal interface in humans

(2018) Roser Vento-Tormo et al.   NATURE

Dapagliflozin and Cardiovascular Outcomes in Type 2 Diabetes

(2018) Stephen D. Wiviott et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cardiomyocyte gene programs encoding morphological and functional signatures in cardiac hypertrophy and failure

(2018) Seitaro Nomura et al.   Nature Communications

Dapagliflozin, a selective SGLT2 Inhibitor, attenuated cardiac fibrosis by regulating the macrophage polarization via STAT3 signaling in infarcted rat hearts

(2017) Tsung-Ming Lee et al.   FREE RADICAL BIOLOGY AND MEDICINE

A single-cell survey of the small intestinal epithelium

(2017) Adam L. Haber et al.   NATURE

IRF3 and type I interferons fuel a fatal response to myocardial infarction

(2017) Kevin R King et al.   NATURE MEDICINE

Single cardiomyocyte nuclear transcriptomes reveal a lincRNA-regulated de-differentiation and cell cycle stress-response in vivo

(2017) Kelvin See et al.   Nature Communications

Single-Cell Resolution of Temporal Gene Expression during Heart Development

(2016) Daniel M. DeLaughter et al.   DEVELOPMENTAL CELL

Activation of the pluripotency factor OCT4 in smooth muscle cells is atheroprotective

(2016) Olga A Cherepanova et al.   NATURE MEDICINE

Anti-Inflammatory and Antiatherogenic Effects of the NLRP3 Inflammasome Inhibitor Arglabin in ApoE2.Ki Mice Fed a High-Fat Diet

(2015) A. Abderrazak et al.   CIRCULATION

Immune Cell and Other Noncardiomyocyte Regulation of Cardiac Hypertrophy and Remodeling

(2015) R. A. Frieler et al.   CIRCULATION

Inhibition of Hypertrophy Is a Good Therapeutic Strategy in Ventricular Pressure Overload

(2015) G. G. Schiattarella et al.   CIRCULATION

Cardiac Nonmyocytes in the Hub of Cardiac Hypertrophy

(2015) T. Kamo et al.   CIRCULATION RESEARCH

A draft network of ligand–receptor-mediated multicellular signalling in human

(2015) Jordan A. Ramilowski et al.   Nature Communications

Allele-Specific Silencing of Mutant Myh6 Transcripts in Mice Suppresses Hypertrophic Cardiomyopathy

(2013) Jianming Jiang et al.   SCIENCE

Molecular basis of physiological heart growth: fundamental concepts and new players

(2012) Marjorie Maillet et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Regulation of Transforming Growth Factor-β1–driven Lung Fibrosis by Galectin-3

(2011) Alison C. MacKinnon et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Galectin-3 deficiency prevents concanavalin A-induced hepatitis in mice

(2011) Vladislav Volarevic et al.   HEPATOLOGY

Chromatin regulation by Brg1 underlies heart muscle development and disease

(2010) Calvin T. Hang et al.   NATURE