The endoplasmic reticulum kinase PERK interacts with the oxidoreductase ERO1 to metabolically adapt mitochondria

Activation of the UPR sensor ATF6α is regulated by its redox-dependent dimerization and ER retention by ERp18

(2022) Ojore Benedict Valentine Oka et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ERO1 alpha deficiency impairs angiogenesis by increasing N-glycosylation of a proangiogenic VEGFA

(2022) Ersilia Varone et al.   Redox Biology

Transfer of H2O2 from Mitochondria to the endoplasmic reticulum via Aquaporin-11

(2022) Ilaria Sorrentino et al.   Redox Biology

MFN2 mediates ER-mitochondrial coupling during ER stress through specialized stable contact sites

(2022) Benjamin Gottschalk et al.   Frontiers in Cell and Developmental Biology

Mitochondria-rough-ER contacts in the liver regulate systemic lipid homeostasis

(2021) Irene Anastasia et al.   Cell Reports

Oxidative bursts of single mitochondria mediate retrograde signaling toward the ER

(2021) David M. Booth et al.   MOLECULAR CELL

Quantification of organelle contact sites by split-GFP-based contact site sensors (SPLICS) in living cells

(2021) Tito Calì et al.   Nature Protocols

A Quantitative Tissue-Specific Landscape of Protein Redox Regulation during Aging

(2020) Haopeng Xiao et al.   CELL

Nox4 regulates InsP 3 receptor‐dependent Ca 2+ release into mitochondria to promote cell survival

(2020) Matteo Beretta et al.   EMBO JOURNAL

The ER chaperone calnexin controls mitochondrial positioning and respiration

(2020) Tomás Gutiérrez et al.   Science Signaling

ER and Nutrient Stress Promote Assembly of Respiratory Chain Supercomplexes through the PERK-eIF2α Axis

(2019) Eduardo Balsa et al.   MOLECULAR CELL

Non-canonical function of IRE1α determines mitochondria-associated endoplasmic reticulum composition to control calcium transfer and bioenergetics

(2019) Amado Carreras-Sureda et al.   NATURE CELL BIOLOGY

Redox signals at the ER –mitochondria interface control melanoma progression

(2019) Xin Zhang et al.   EMBO JOURNAL

IP3 receptor isoforms differently regulate ER-mitochondrial contacts and local calcium transfer

(2019) Adam Bartok et al.   Nature Communications

Human aquaporin-11 guarantees efficient transport of H2O2 across the endoplasmic reticulum membrane

(2019) Stefano Bestetti et al.   Redox Biology

The PERK Arm of the Unfolded Protein Response Regulates Mitochondrial Morphology during Acute Endoplasmic Reticulum Stress

(2018) Justine Lebeau et al.   Cell Reports

The enigmatic ATP supply of the endoplasmic reticulum

(2018) Maria R. Depaoli et al.   BIOLOGICAL REVIEWS

Optimization of normal phase chromatographic conditions for lipid analysis and comparison of associated detection techniques

(2017) Sonia Abreu et al.   JOURNAL OF CHROMATOGRAPHY A

The ER Stress Sensor PERK Coordinates ER-Plasma Membrane Contact Site Formation through Interaction with Filamin-A and F-Actin Remodeling

(2017) Alexander R. van Vliet et al.   MOLECULAR CELL

PDI is an essential redox-sensitive activator of PERK during the unfolded protein response (UPR)

(2017) Philip Kranz et al.   Cell Death & Disease

An Update on Sec61 Channel Functions, Mechanisms, and Related Diseases

(2017) Sven Lang et al.   Frontiers in Physiology

Development of a stable ERroGFP variant suitable for monitoring redox dynamics in the ER

(2016) J. Hoseki et al.   BIOSCIENCE REPORTS

FATE1 antagonizes calcium‐ and drug‐induced apoptosis by uncoupling ER and mitochondria

(2016) Mabrouka Doghman‐Bouguerra et al.   EMBO REPORTS

TMX1 determines cancer cell metabolism as a thiol-based modulator of ER–mitochondria Ca2+flux

(2016) Arun Raturi et al.   JOURNAL OF CELL BIOLOGY

Redox Nanodomains Are Induced by and Control Calcium Signaling at the ER-Mitochondrial Interface

(2016) David M. Booth et al.   MOLECULAR CELL

Mitochondria-associated endoplasmic reticulum membranes allow adaptation of mitochondrial metabolism to glucose availability in the liver

(2016) Pierre Theurey et al.   Journal of Molecular Cell Biology

Cysteines 208 and 241 in Ero1α are required for maximal catalytic turnover

(2016) Thomas Ramming et al.   Redox Biology

ERO1-independent production of H2O2within the endoplasmic reticulum fuels Prdx4-mediated oxidative protein folding

(2015) Tasuku Konno et al.   JOURNAL OF CELL BIOLOGY

Red fluorescent genetically encoded Ca2+indicators for use in mitochondria and endoplasmic reticulum

(2014) Jiahui Wu et al.   BIOCHEMICAL JOURNAL

Mitochondria-Associated Endoplasmic Reticulum Membrane (MAM) Integrity Is Required for Insulin Signaling and Is Implicated in Hepatic Insulin Resistance

(2014) E. Tubbs et al.   DIABETES

pHuji, a pH-sensitive red fluorescent protein for imaging of exo- and endocytosis

(2014) Yi Shen et al.   JOURNAL OF CELL BIOLOGY

Chronic enrichment of hepatic endoplasmic reticulum–mitochondria contact leads to mitochondrial dysfunction in obesity

(2014) Ana Paula Arruda et al.   NATURE MEDICINE

ER–mitochondria associations are regulated by the VAPB–PTPIP51 interaction and are disrupted by ALS/FTD-associated TDP-43

(2014) Radu Stoica et al.   Nature Communications

MAM (mitochondria-associated membranes) in mammalian cells: Lipids and beyond

(2013) Jean E. Vance   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Regulation of inositol 1,4,5-trisphosphate receptors during endoplasmic reticulum stress

(2013) Santeri Kiviluoto et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Mfn2 modulates the UPR and mitochondrial function via repression of PERK

(2013) Juan Pablo Muñoz et al.   EMBO JOURNAL

ATP increases within the lumen of the endoplasmic reticulum upon intracellular Ca2+ release

(2013) Neelanjan Vishnu et al.   MOLECULAR BIOLOGY OF THE CELL

Protein Folding in the Endoplasmic Reticulum

(2013) I. Braakman et al.   Cold Spring Harbor Perspectives in Biology

Pharmacological brake-release of mRNA translation enhances cognitive memory

(2013) Carmela Sidrauski et al.   eLife

Green fluorescent protein-based monitoring of endoplasmic reticulum redox poise

(2013) Julia Birk et al.   Frontiers in Genetics

Redox Regulation of Sodium and Calcium Handling

(2012) Stefan Wagner et al.   ANTIOXIDANTS & REDOX SIGNALING

Where the endoplasmic reticulum and the mitochondrion tie the knot: The mitochondria-associated membrane (MAM)

(2012) Arun Raturi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

PERK is required at the ER-mitochondrial contact sites to convey apoptosis after ROS-based ER stress

(2012) T Verfaillie et al.   CELL DEATH AND DIFFERENTIATION

Assessing mitochondrial dysfunction in cells

(2011) Martin D. Brand et al.   BIOCHEMICAL JOURNAL

Molecular Bases of Cyclic and Specific Disulfide Interchange between Human ERO1α Protein and Protein-disulfide Isomerase (PDI)

(2011) Shoji Masui et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Increased ER-mitochondrial coupling promotes mitochondrial respiration and bioenergetics during early phases of ER stress

(2011) R. Bravo et al.   JOURNAL OF CELL SCIENCE

During autophagy mitochondria elongate, are spared from degradation and sustain cell viability

(2011) Ligia C. Gomes et al.   NATURE CELL BIOLOGY

Essential Regulation of Cell Bioenergetics by Constitutive InsP3 Receptor Ca2+ Transfer to Mitochondria

(2010) César Cárdenas et al.   CELL

Ero1α requires oxidizing and normoxic conditions to localize to the mitochondria-associated membrane (MAM)

(2010) Susanna Y. Gilady et al.   CELL STRESS & CHAPERONES

Human δ opioid receptor biogenesis is regulated via interactions with SERCA2b and calnexin

(2010) Jussi T. Tuusa et al.   FEBS Journal

A Small Molecule Inhibitor of Endoplasmic Reticulum Oxidation 1 (ERO1) with Selectively Reversible Thiol Reactivity

(2010) Jaime D. Blais et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Oxidative Protein Folding by an Endoplasmic Reticulum-Localized Peroxiredoxin

(2010) Ester Zito et al.   MOLECULAR CELL

Isolation of mitochondria-associated membranes and mitochondria from animal tissues and cells

(2009) Mariusz R Wieckowski et al.   Nature Protocols

The Subcellular Distribution of Calnexin Is Mediated by PACS-2

(2008) Nathan Myhill et al.   MOLECULAR BIOLOGY OF THE CELL

Mitofusin 2 tethers endoplasmic reticulum to mitochondria

(2008) Olga Martins de Brito et al.   NATURE