Mitochondria-rough-ER contacts in the liver regulate systemic lipid homeostasis

mTOR at the nexus of nutrition, growth, ageing and disease

(2020) Grace Y. Liu et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Correlative three-dimensional super-resolution and block-face electron microscopy of whole vitreously frozen cells

(2020) David P. Hoffman et al.   SCIENCE

Endoplasmic reticulum contact sites regulate the dynamics of membraneless organelles

(2020) Jason E. Lee et al.   SCIENCE

Controlled division of cell-sized vesicles by low densities of membrane-bound proteins

(2020) Jan Steinkühler et al.   Nature Communications

Dietary fructose feeds hepatic lipogenesis via microbiota-derived acetate

(2020) Steven Zhao et al.   NATURE

Ribosome-associated vesicles: A dynamic subcompartment of the endoplasmic reticulum in secretory cells

(2020) Stephen D. Carter et al.   Science Advances

Coming together to define membrane contact sites

(2019) Luca Scorrano et al.   Nature Communications

Deficient Endoplasmic Reticulum-Mitochondrial Phosphatidylserine Transfer Causes Liver Disease

(2019) María Isabel Hernández-Alvarez et al.   CELL

The cell biology of the hepatocyte: A membrane trafficking machine

(2019) Ryan J. Schulze et al.   JOURNAL OF CELL BIOLOGY

Spastin tethers lipid droplets to peroxisomes and directs fatty acid trafficking through ESCRT-III

(2019) Chi-Lun Chang et al.   JOURNAL OF CELL BIOLOGY

Moving beyond P values: data analysis with estimation graphics

(2019) Joses Ho et al.   NATURE METHODS

Nanoresolution real-time 3D orbital tracking for studying mitochondrial trafficking in vertebrate axons in vivo

(2019) Fabian Wehnekamp et al.   eLife

NPC1 regulates ER contacts with endocytic organelles to mediate cholesterol egress

(2019) D. Höglinger et al.   Nature Communications

OUP accepted manuscript

(2018)   BIOINFORMATICS

Mitochondria Bound to Lipid Droplets Have Unique Bioenergetics, Composition, and Dynamics that Support Lipid Droplet Expansion

(2018) Ilan Y. Benador et al.   Cell Metabolism

Mitochondria–lysosome contacts regulate mitochondrial fission via RAB7 GTP hydrolysis

(2018) Yvette C. Wong et al.   NATURE

NUFIP1 is a ribosome receptor for starvation-induced ribophagy

(2018) Gregory A. Wyant et al.   SCIENCE

Mitochondria are transported along microtubules in membrane nanotubes to rescue distressed cardiomyocytes from apoptosis

(2018) Jing Shen et al.   Cell Death & Disease

Aster Proteins Facilitate Nonvesicular Plasma Membrane to ER Cholesterol Transport in Mammalian Cells

(2018) Jaspreet Sandhu et al.   CELL

Rho-kinase/AMPK axis regulates hepatic lipogenesis during overnutrition

(2018) Hu Huang et al.   JOURNAL OF CLINICAL INVESTIGATION

Linking cellular stress responses to systemic homeostasis

(2018) Lorenzo Galluzzi et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Alirocumab and Cardiovascular Outcomes after Acute Coronary Syndrome

(2018) Gregory G. Schwartz et al.   NEW ENGLAND JOURNAL OF MEDICINE

MITO-Tag Mice enable rapid isolation and multimodal profiling of mitochondria from specific cell types in vivo

(2018) Erol C. Bayraktar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hepatitis C Virus Lipoviroparticles Assemble in the Endoplasmic Reticulum (ER) and Bud off from the ER to the Golgi Compartment in COPII Vesicles

(2017) Gulam H. Syed et al.   JOURNAL OF VIROLOGY

Sphingomyelin metabolism controls the shape and function of the Golgi cisternae

(2017) Felix Campelo et al.   eLife

Proteomic mapping of cytosol-facing outer mitochondrial and ER membranes in living human cells by proximity biotinylation

(2017) Victoria Hung et al.   eLife

Brain Control of Plasma Cholesterol Involves Polysialic Acid Molecules in the Hypothalamus

(2017) Xavier Brenachot et al.   Frontiers in Neuroscience

MultiQC: summarize analysis results for multiple tools and samples in a single report

(2016) Philip Ewels et al.   BIOINFORMATICS

Endosome-ER Contacts Control Actin Nucleation and Retromer Function through VAP-Dependent Regulation of PI4P

(2016) Rui Dong et al.   CELL

The coming of age of the mitochondria–ER contact: a matter of thickness

(2016) M Giacomello et al.   CELL DEATH AND DIFFERENTIATION

Mitochondrial Dynamics Impacts Stem Cell Identity and Fate Decisions by Regulating a Nuclear Transcriptional Program

(2016) Mireille Khacho et al.   Cell Stem Cell

Effects of PCSK9 Inhibition With Alirocumab on Lipoprotein Metabolism in Healthy HumansClinical Perspective

(2016) Gissette Reyes-Soffer et al.   CIRCULATION

Polyhedral 3D structure of human plasma very low density lipoproteins by individual particle cryo-electron tomography1

(2016) Yadong Yu et al.   JOURNAL OF LIPID RESEARCH

Near-optimal probabilistic RNA-seq quantification

(2016) Nicolas L Bray et al.   NATURE BIOTECHNOLOGY

Critical reappraisal confirms that Mitofusin 2 is an endoplasmic reticulum–mitochondria tether

(2016) Deborah Naon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Increased spatiotemporal resolution reveals highly dynamic dense tubular matrices in the peripheral ER

(2016) J. Nixon-Abell et al.   SCIENCE

Mitochondria-associated endoplasmic reticulum membranes allow adaptation of mitochondrial metabolism to glucose availability in the liver

(2016) Pierre Theurey et al.   Journal of Molecular Cell Biology

Sex- and tissue-specific changes in mTOR signaling with age in C57BL/6J mice

(2015) Emma L. Baar et al.   AGING CELL

New Insights into the Regulation of Chylomicron Production

(2015) Satya Dash et al.   Annual Review of Nutrition

Cholesterol Transport through Lysosome-Peroxisome Membrane Contacts

(2015) Bei-Bei Chu et al.   CELL

A Century of Cholesterol and Coronaries: From Plaques to Genes to Statins

(2015) Joseph L. Goldstein et al.   CELL

Distinct mechanisms controlling rough and smooth endoplasmic reticulum contacts with mitochondria

(2015) P. T. C. Wang et al.   JOURNAL OF CELL SCIENCE

In vivo imaging of axonal transport of mitochondria in the diseased and aged mammalian CNS

(2015) Yuji Takihara et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CX3CR1 deficiency promotes muscle repair and regeneration by enhancing macrophage ApoE production

(2015) Ludovic Arnold et al.   Nature Communications

A sterol-enriched vacuolar microdomain mediates stationary phase lipophagy in budding yeast

(2014) Chao-Wen Wang et al.   JOURNAL OF CELL BIOLOGY

Dynamics of Mitochondrial DNA Nucleoids Regulated by Mitochondrial Fission Is Essential for Maintenance of Homogeneously Active Mitochondria during Neonatal Heart Development

(2014) Takaya Ishihara et al.   MOLECULAR AND CELLULAR BIOLOGY

Exome-wide association study identifies a TM6SF2 variant that confers susceptibility to nonalcoholic fatty liver disease

(2014) Julia Kozlitina et al.   NATURE GENETICS

Chronic enrichment of hepatic endoplasmic reticulum–mitochondria contact leads to mitochondrial dysfunction in obesity

(2014) Ana Paula Arruda et al.   NATURE MEDICINE

Reduction of VLDL Secretion Decreases Cholesterol Excretion in Niemann-Pick C1-Like 1 Hepatic Transgenic Mice

(2014) Stephanie M. Marshall et al.   PLoS One

A Mitofusin-2–dependent inactivating cleavage of Opa1 links changes in mitochondriacristaeand ER contacts in the postprandial liver

(2014) Aditi Sood et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Determining the Gaussian Curvature Modulus of Lipid Membranes in Simulations

(2012) Mingyang Hu et al.   BIOPHYSICAL JOURNAL

The Role of Endoplasmic Reticulum in Hepatic Lipid Homeostasis and Stress Signaling

(2012) Suneng Fu et al.   Cell Metabolism

Human thyroxine binding globulin (TBG) promoter directs efficient and sustaining transgene expression in liver-specific pattern

(2012) Zhonghai Yan et al.   GENE

Mitochondrial transport in neurons: impact on synaptic homeostasis and neurodegeneration

(2012) Zu-Hang Sheng et al.   NATURE REVIEWS NEUROSCIENCE

Curvature of Double-Membrane Organelles Generated by Changes in Membrane Size and Composition

(2012) Roland L. Knorr et al.   PLoS One

ER Tubules Mark Sites of Mitochondrial Division

(2011) J. R. Friedman et al.   SCIENCE

Loss of TGH/Ces3 in Mice Decreases Blood Lipids, Improves Glucose Tolerance, and Increases Energy Expenditure

(2010) Enhui Wei et al.   Cell Metabolism

A Macrophage Sterol-Responsive Network Linked to Atherogenesis

(2010) Lev Becker et al.   Cell Metabolism

Mitochondrial fusion and fission in cell life and death

(2010) Benedikt Westermann   NATURE REVIEWS MOLECULAR CELL BIOLOGY

FastTree 2 – Approximately Maximum-Likelihood Trees for Large Alignments

(2010) Morgan N. Price et al.   PLoS One

The Mechanism of Ca2+-Dependent Regulation of Kinesin-Mediated Mitochondrial Motility

(2009) Xinnan Wang et al.   CELL

VLDL exits from the endoplasmic reticulum in a specialized vesicle, the VLDL transport vesicle, in rat primary hepatocytes

(2008) Shadab A. Siddiqi   BIOCHEMICAL JOURNAL

Lipid droplets are arrested in the ER membrane by tight binding of lipidated apolipoprotein B-100

(2008) Y. Ohsaki et al.   JOURNAL OF CELL SCIENCE

Mitofusin 2 tethers endoplasmic reticulum to mitochondria

(2008) Olga Martins de Brito et al.   NATURE

The evolution of cell types in animals: emerging principles from molecular studies

(2008) Detlev Arendt   NATURE REVIEWS GENETICS