Persistent Endoplasmic Reticulum Stress Stimulated by Peptide Assemblies for Sensitizing Cancer Chemotherapy

ER-Targeting Cyanine Dye as an NIR Photoinducer to Efficiently Trigger Photoimmunogenic Cancer Cell Death

(2022) He Ma et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Dendritic Polymer‐Based Nanosystem Mediates Drug Penetration and Irreversible Endoplasmic Reticulum Stresses in Tumor via Neighboring Effect

(2022) Xiuli Zheng et al.   ADVANCED MATERIALS

Tailoring a Nanochaperone to Regulate α‐Synuclein Assembly

(2022) Xiaohui Wu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Self-Amplifying Assembly of Peptides in Macrophages for Enhanced Inflammatory Treatment

(2022) Yanqiu Song et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

In Situ Self-Sorting Peptide Assemblies in Living Cells for Simultaneous Organelle Targeting

(2022) Xin Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Designing bioresponsive nanomaterials for intracellular self-assembly

(2022) Sarah Chagri et al.   Nature Reviews Chemistry

Enzymatic Assemblies of Thiophosphopeptides Instantly Target Golgi Apparatus and Selectively Kill Cancer Cells**

(2021) Weiyi Tan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Microtubule-Targeted Self-Assembly Triggers Prometaphase–Metaphase Oscillations Suppressing Tumor Growth

(2021) Guanying Li et al.   NANO LETTERS

Amyloid-type Protein Aggregation and Prion-like Properties of Amyloids

(2021) Dieter Willbold et al.   CHEMICAL REVIEWS

Peptide-Based Supramolecular Systems Chemistry

(2021) Fahmeed Sheehan et al.   CHEMICAL REVIEWS

Noncanonical Amino Acids for Hypoxia-Responsive Peptide Self-Assembly and Fluorescence

(2021) Binbin Hu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Supramolecular Antagonists Promote Mitochondrial Dysfunction

(2021) Mingming Li et al.   NANO LETTERS

Binding-Induced Fibrillogenesis Peptides Recognize and Block Intracellular Vimentin Skeletonization against Breast Cancer

(2021) Jia-Qi Fan et al.   NANO LETTERS

Metal–Phenolic‐Network‐Coated Dendrimer–Drug Conjugates for Tumor MR Imaging and Chemo/Chemodynamic Therapy via Amplification of Endoplasmic Reticulum Stress

(2021) Zhiqiang Wang et al.   ADVANCED MATERIALS

Peptide Design and Self-assembly into Targeted Nanostructure and Functional Materials

(2021) Nairiti J. Sinha et al.   CHEMICAL REVIEWS

Pharmacological targeting of endoplasmic reticulum stress in disease

(2021) Stefan J. Marciniak et al.   NATURE REVIEWS DRUG DISCOVERY

The α-synuclein hereditary mutation E46K unlocks a more stable, pathogenic fibril structure

(2020) David R. Boyer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanisms, regulation and functions of the unfolded protein response

(2020) Claudio Hetz et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Enzymatic Noncovalent Synthesis

(2020) Hongjian He et al.   CHEMICAL REVIEWS

Biomimetic peptide self-assembly for functional materials

(2020) Aviad Levin et al.   Nature Reviews Chemistry

An ER‐Targeting Iridium(III) Complex That Induces Immunogenic Cell Death in Non‐Small‐Cell Lung Cancer

(2020) Lili Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

In vivo self-assembled nanomedicine

(2020) Muhetaerjiang Mamuti et al.   Nano Today

Structural basis for pH-dependent retrieval of ER proteins from the Golgi by the KDEL receptor

(2019) Philipp Bräuer et al.   SCIENCE

Ubiquitin Signaling and Degradation of Aggregate-Prone Proteins

(2019) Margarita Galves et al.   TRENDS IN BIOCHEMICAL SCIENCES

Proline Isomerization-Regulated Tumor Microenvironment-Adaptable Self-Assembly of Peptides for Enhanced Therapeutic Efficacy

(2019) Mingming Li et al.   NANO LETTERS

Peptide and protein nanoparticle conjugates: versatile platforms for biomedical applications

(2018) Christopher D. Spicer et al.   CHEMICAL SOCIETY REVIEWS

Enzymatic Assemblies Disrupt Membrane and Target Endoplasmic Reticulum (ER) for Selective Cancer Cell Death

(2018) Zhaoqianqi Feng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Unfolded Protein Response and Cell Fate Control

(2018) Claudio Hetz et al.   MOLECULAR CELL

Recent Advances in Subcellular Targeted Cancer Therapy Based on Functional Materials

(2018) Wei-Hai Chen et al.   ADVANCED MATERIALS

Immune Responsive Release of Tacrolimus to Overcome Organ Transplant Rejection

(2018) Jindao Wu et al.   ADVANCED MATERIALS

Instructed Assembly of Peptides for Intracellular Enzyme Sequestration

(2018) Zhaoqianqi Feng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

KDEL Receptors Are Differentially Regulated to Maintain the ER Proteome under Calcium Deficiency

(2018) Kathleen A. Trychta et al.   Cell Reports

Proteasome inhibitors in cancer therapy

(2017) Elisabet E. Manasanch et al.   Nature Reviews Clinical Oncology

Toyocamycin induces apoptosis via the crosstalk between reactive oxygen species and p38/ERK MAPKs signaling pathway in human prostate cancer PC-3 cells

(2017) Sul-Gi Park et al.   Pharmacological Reports

Mitochondria localization induced self-assembly of peptide amphiphiles for cellular dysfunction

(2017) M. T. Jeena et al.   Nature Communications

Tuning One-Dimensional Nanostructures of Bola-Like Peptide Amphiphiles by Varying the Hydrophilic Amino Acids

(2016) Yurong Zhao et al.   CHEMISTRY-A EUROPEAN JOURNAL

Integrating Enzymatic Self-Assembly and Mitochondria Targeting for Selectively Killing Cancer Cells without Acquired Drug Resistance

(2016) Huaimin Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Protein misfolding in the endoplasmic reticulum as a conduit to human disease

(2016) Miao Wang et al.   NATURE

Electrostatic-Driven Lamination and Untwisting of β-Sheet Assemblies

(2015) Yang Hu et al.   ACS Nano

KIAA1324 Suppresses Gastric Cancer Progression by Inhibiting the Oncoprotein GRP78

(2015) J. M. Kang et al.   CANCER RESEARCH

Cationic polystyrene nanospheres induce autophagic cell death through the induction of endoplasmic reticulum stress

(2015) Hui-Wen Chiu et al.   Nanoscale

Endoplasmic Reticulum Stress-Activated Cell Reprogramming in Oncogenesis

(2015) E. Chevet et al.   Cancer Discovery

MSN-Mediated Sequential Vascular-to-Cell Nuclear-Targeted Drug Delivery for Efficient Tumor Regression

(2014) Limin Pan et al.   ADVANCED MATERIALS

Proteostasis impairment in protein-misfolding and -aggregation diseases

(2014) Mark S. Hipp et al.   TRENDS IN CELL BIOLOGY

A Peptidic Unconjugated GRP78/BiP Ligand Modulates the Unfolded Protein Response and Induces Prostate Cancer Cell Death

(2012) Danilo Maddalo et al.   PLoS One

Identification of Toyocamycin, an agent cytotoxic for multiple myeloma cells, as a potent inhibitor of ER stress-induced XBP1 mRNA splicing

(2012) M Ri et al.   Blood Cancer Journal

Misfolded proteins in Alzheimer's disease and type II diabetes

(2011) Alaina S. DeToma et al.   CHEMICAL SOCIETY REVIEWS