In vivo self-assembled nanomedicine

A Near-Infrared Peptide Probe with Tumor-Specific Excretion-Retarded Effect for Image-Guided Surgery of Renal Cell Carcinoma

(2020) Hong-Wei An et al.   ACS Nano

Reversible Thermochromic Nanoparticles Composed of a Eutectic Mixture for Temperature-Controlled Photothermal Therapy

(2020) Song Shen et al.   NANO LETTERS

Transformable peptide nanoparticles arrest HER2 signalling and cause cancer cell death in vivo

(2020) Lu Zhang et al.   Nature Nanotechnology

Self-assembly of pentapeptides into morphology-adaptable nanomedicines for enhanced combinatorial chemo-photodynamic therapy

(2020) Zhifei Cheng et al.   Nano Today

Theranostic multimodal gold nanoclusters

(2020) Gang He et al.   Nature Biomedical Engineering

Reduction Triggered In Situ Polymerization in Living Mice

(2020) Lina Cui et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Clinical cancer nanomedicine

(2019) Joy Wolfram et al.   Nano Today

γ-Glutamyltranspeptidase-Triggered Intracellular Gadolinium Nanoparticle Formation Enhances the T2-Weighted MR Contrast of Tumor

(2019) Zijuan Hai et al.   NANO LETTERS

Autocatalytic Morphology Transformation Platform for Targeted Drug Accumulation

(2019) Dong-Bing Cheng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Secreted PD-L1 variants mediate resistance to PD-L1 blockade therapy in non–small cell lung cancer

(2019) Bo Gong et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Microenvironment-Induced In Situ Self-Assembly of Polymer-Peptide Conjugates That Attack Solid Tumors Deeply

(2019) Yong Cong et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Peptide Tectonics: Encoded Structural Complementarity Dictates Programmable Self‐Assembly

(2019) Shaofeng Lou et al.   Advanced Science

Enzyme-Instructed Peptide Assemblies Selectively Inhibit Bone Tumors

(2019) Zhaoqianqi Feng et al.   Chem

New power of self-assembling carbonic anhydrase inhibitor: Short peptide–constructed nanofibers inspire hypoxic cancer therapy

(2019) Jiayang Li et al.   Science Advances

In Situ Self-Assembled Nanofibers Precisely Target Cancer-Associated Fibroblasts for Improved Tumor Imaging

(2019) Xiao-Xiao Zhao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

In vivo cancer targeting via glycopolyester nanoparticle mediated metabolic cell labeling followed by click reaction

(2019) Hua Wang et al.   BIOMATERIALS

Proline Isomerization-Regulated Tumor Microenvironment-Adaptable Self-Assembly of Peptides for Enhanced Therapeutic Efficacy

(2019) Mingming Li et al.   NANO LETTERS

Furin-mediated intracellular self-assembly of olsalazine nanoparticles for enhanced magnetic resonance imaging and tumour therapy

(2019) Yue Yuan et al.   NATURE MATERIALS

A tumour-selective cascade activatable self-detained system for drug delivery and cancer imaging

(2019) Hong-Wei An et al.   Nature Communications

Engineered nanomedicines with enhanced tumor penetration

(2019) Jianxun Ding et al.   Nano Today

Cross-Linked Fluorescent Supramolecular Nanoparticles for Intradermal Controlled Release of Antifungal Drug—A Therapeutic Approach for Onychomycosis

(2018) Fang Wang et al.   ACS Nano

Tandem Molecular Self-Assembly in Liver Cancer Cells

(2018) Jie Zhan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enzymatic Cleavage of Branched Peptides for Targeting Mitochondria

(2018) Hongjian He et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nanomedicine for tumor microenvironment modulation and cancer treatment enhancement

(2018) Jingjing Liu et al.   Nano Today

Progress and challenges towards targeted delivery of cancer therapeutics

(2018) Daniel Rosenblum et al.   Nature Communications

Chemotaxis-Instructed Intracellular Staphylococcus aureus Infection Detection by a Targeting and Self-Assembly Signal-Enhanced Photoacoustic Probe

(2018) Qian Cai et al.   NANO LETTERS

Near-Infrared Laser-Driven in Situ Self-Assembly as a General Strategy for Deep Tumor Therapy

(2018) Fu-Hua Liu et al.   NANO LETTERS

Applications of CBT-Cys click reaction: past, present, and future

(2018) Miaomiao Zhang et al.   Science China-Chemistry

Transport and interactions of nanoparticles in the kidneys

(2018) Bujie Du et al.   Nature Reviews Materials

Restoration of tumour-growth suppression in vivo via systemic nanoparticle-mediated delivery of PTEN mRNA

(2018) Mohammad Ariful Islam et al.   Nature Biomedical Engineering

Biomolecular Assemblies: Moving from Observation to Predictive Design

(2018) Corey J. Wilson et al.   CHEMICAL REVIEWS

Alkaline Phosphatase-Triggered Self-Assembly of Near-Infrared Nanoparticles for the Enhanced Photoacoustic Imaging of Tumors

(2018) Chengfan Wu et al.   NANO LETTERS

Synergistic enzymatic and bioorthogonal reactions for selective prodrug activation in living systems

(2018) Qingxin Yao et al.   Nature Communications

Sulfated glycopeptide nanostructures for multipotent protein activation

(2017) Sungsoo S. Lee et al.   Nature Nanotechnology

Tumor-targeted nanomedicines for cancer theranostics

(2017) Alexandra G. Arranja et al.   PHARMACOLOGICAL RESEARCH

Intracellular construction of topology-controlled polypeptide nanostructures with diverse biological functions

(2017) Li-Li Li et al.   Nature Communications

Thermo-Controlled in Situ Phase Transition of Polymer–Peptides on Cell Surfaces for High-Performance Proliferative Inhibition

(2016) Sheng-Lin Qiao et al.   ACS Applied Materials & Interfaces

Integrating Enzymatic Self-Assembly and Mitochondria Targeting for Selectively Killing Cancer Cells without Acquired Drug Resistance

(2016) Huaimin Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nanomedicine and tumor heterogeneity: Concept and complex reality

(2016) Sandra N. Ekdawi et al.   Nano Today

The role of nanotechnology in the development of battery materials for electric vehicles

(2016) Jun Lu et al.   Nature Nanotechnology

Pathological-Condition-Driven Construction of Supramolecular Nanoassemblies for Bacterial Infection Detection

(2015) Li-Li Li et al.   ADVANCED MATERIALS

In Situ Formation of Nanofibers from Purpurin18-Peptide Conjugates and the Assembly Induced Retention Effect in Tumor Sites

(2015) Di Zhang et al.   ADVANCED MATERIALS

Enzyme-Instructed Self-Assembly: A Multistep Process for Potential Cancer Therapy

(2015) Jie Zhou et al.   BIOCONJUGATE CHEMISTRY

Controlling Cancer Cell Fate Using Localized Biocatalytic Self-Assembly of an Aromatic Carbohydrate Amphiphile

(2015) Ricardo A. Pires et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Current Approaches for Improving Intratumoral Accumulation and Distribution of Nanomedicines

(2015) Mikhail O Durymanov et al.   Theranostics

Enzyme-Responsive Release of Doxorubicin from Monodisperse Dipeptide-Based Nanocarriers for Highly Efficient Cancer Treatment In Vitro

(2014) He Zhang et al.   ADVANCED FUNCTIONAL MATERIALS

Bioorthogonal cyclization-mediated in situ self-assembly of small-molecule probes for imaging caspase activity in vivo

(2014) Deju Ye et al.   Nature Chemistry

Dephosphorylation of d-Peptide Derivatives to Form Biofunctional, Supramolecular Nanofibers/Hydrogels and Their Potential Applications for Intracellular Imaging and Intratumoral Chemotherapy

(2013) Jiayang Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

DNA nanomedicine: Engineering DNA as a polymer for therapeutic and diagnostic applications

(2010) Michael J. Campolongo et al.   ADVANCED DRUG DELIVERY REVIEWS

Exploiting biocatalysis in peptide self-assembly

(2010) Richard J. Williams et al.   BIOPOLYMERS

Synthesis of pH-responsive hydrophobically-modified hydrogels of poly(methacrylic acid-co-diallylammonium salt) in aqueous solution

(2010) Dang-Ge Gao et al.   NEW JOURNAL OF CHEMISTRY

A biocompatible condensation reaction for controlled assembly of nanostructures in living cells

(2009) Gaolin Liang et al.   Nature Chemistry

Controlled release of functional proteins through designer self-assembling peptide nanofiber hydrogel scaffold

(2009) S. Koutsopoulos et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fitting Neurological Protein Aggregation Kinetic Data via a 2-Step, Minimal/“Ockham's Razor” Model:  The Finke−Watzky Mechanism of Nucleation Followed by Autocatalytic Surface Growth†

(2008) Aimee M. Morris et al.   BIOCHEMISTRY

The effect of shape on the margination dynamics of non-neutrally buoyant particles in two-dimensional shear flows

(2008) F. Gentile et al.   JOURNAL OF BIOMECHANICS

Clearance properties of nano-sized particles and molecules as imaging agents: considerations and caveats

(2008) Michelle Longmire et al.   Nanomedicine