Chromosome fragility and the abnormal replication of the FMR1 locus in fragile X syndrome

Unraveling cell type–specific and reprogrammable human replication origin signatures associated with G-quadruplex consensus motifs

(2012) Emilie Besnard et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Open Sesame: activating dormant replication origins in the mouse immunoglobulin heavy chain (Igh) locus

(2011) James A Borowiec et al.   CURRENT OPINION IN CELL BIOLOGY

Genome-wide depletion of replication initiation events in highly transcribed regions

(2011) M. M. Martin et al.   GENOME RESEARCH

Genome-scale analysis of metazoan replication origins reveals their organization in specific but flexible sites defined by conserved features

(2011) C. Cayrou et al.   GENOME RESEARCH

Failure of Origin Activation in Response to Fork Stalling Leads to Chromosomal Instability at Fragile Sites

(2011) Efrat Ozeri-Galai et al.   MOLECULAR CELL

Cell-type-specific replication initiation programs set fragility of the FRA3B fragile site

(2011) Anne Letessier et al.   NATURE

Integrative genomics viewer

(2011) James T Robinson et al.   NATURE BIOTECHNOLOGY

CGG repeats associated with fragile X chromosome form left-handed Z-DNA structure

(2010) Daniel Renčiuk et al.   BIOPOLYMERS

Inhibition of topoisomerase I prevents chromosome breakage at common fragile sites

(2010) Martin F. Arlt et al.   DNA REPAIR

Evolutionarily conserved replication timing profiles predict long-range chromatin interactions and distinguish closely related cell types

(2010) T. Ryba et al.   GENOME RESEARCH

Fragile X prenatal analyses show full mutation females at high risk for mosaic Turner syndrome: Fragile X leads to chromosome loss

(2009) Carl Dobkin et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Impaired replication dynamics at the FRA3B common fragile site

(2009) Aparna Palakodeti et al.   HUMAN MOLECULAR GENETICS

Replisome stalling and stabilization at CGG repeats, which are responsible for chromosomal fragility

(2009) Irina Voineagu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The role of DNA damage response pathways in chromosome fragility in Fragile X syndrome

(2009) D. Kumari et al.   NUCLEIC ACIDS RESEARCH

Sequencing newly replicated DNA reveals widespread plasticity in human replication timing

(2009) R. S. Hansen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transcription Initiation Activity Sets Replication Origin Efficiency in Mammalian Cells

(2009) Joana Sequeira-Mendes et al.   PLoS Genetics

Human chromosome fragility

(2007) T. Lukusa et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms