Dendritic spine dysgenesis in Rett syndrome

MeCP2 Suppresses Nuclear MicroRNA Processing and Dendritic Growth by Regulating the DGCR8/Drosha Complex

(2014) Tian-Lin Cheng et al.   DEVELOPMENTAL CELL

BDNF mimetic compound LM22A-4 regulates cementoblast differentiation via the TrkB–ERK/Akt signaling cascade

(2014) Mikihito Kajiya et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Dendritic Spines: The Locus of Structural and Functional Plasticity

(2014) Carlo Sala et al.   PHYSIOLOGICAL REVIEWS

Functional recovery with recombinant human IGF1 treatment in a mouse model of Rett Syndrome

(2014) Jorge Castro et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Safety, pharmacokinetics, and preliminary assessment of efficacy of mecasermin (recombinant human IGF-1) for the treatment of Rett syndrome

(2014) O. S. Khwaja et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A selective histone deacetylase-6 inhibitor improves BDNF trafficking in hippocampal neurons from Mecp2 knockout mice: implications for Rett syndrome

(2014) Xin Xu et al.   Frontiers in Cellular Neuroscience

Developmental and maintenance defects in Rett syndrome neurons identified by a new mouse staging system in vitro

(2014) Gabriele Baj et al.   Frontiers in Cellular Neuroscience

Insulinotropic treatments exacerbate metabolic syndrome in mice lacking MeCP2 function

(2013) Meagan R. Pitcher et al.   HUMAN MOLECULAR GENETICS

Actin filaments and microtubules in dendritic spines

(2013) Tomoaki Shirao et al.   JOURNAL OF NEUROCHEMISTRY

Dendritic Arborization and Spine Dynamics Are Abnormal in the Mouse Model of MECP2 Duplication Syndrome

(2013) M. Jiang et al.   JOURNAL OF NEUROSCIENCE

A Small Molecule TrkB Ligand Reduces Motor Impairment and Neuropathology in R6/2 and BACHD Mouse Models of Huntington's Disease

(2013) D. A. Simmons et al.   JOURNAL OF NEUROSCIENCE

Dendritic spines: from structure to in vivo function

(2012) Nathalie L Rochefort et al.   EMBO REPORTS

A Critical and Cell-Autonomous Role for MeCP2 in Synaptic Scaling Up

(2012) M. P. Blackman et al.   JOURNAL OF NEUROSCIENCE

MeCP2 Is Critical for Maintaining Mature Neuronal Networks and Global Brain Anatomy during Late Stages of Postnatal Brain Development and in the Mature Adult Brain

(2012) M. V. C. Nguyen et al.   JOURNAL OF NEUROSCIENCE

The Rett Syndrome Protein MeCP2 Regulates Synaptic Scaling

(2012) Z. Qiu et al.   JOURNAL OF NEUROSCIENCE

A TrkB Small Molecule Partial Agonist Rescues TrkB Phosphorylation Deficits and Improves Respiratory Function in a Mouse Model of Rett Syndrome

(2012) D. A. Schmid et al.   JOURNAL OF NEUROSCIENCE

Sustained expression of brain-derived neurotrophic factor is required for maintenance of dendritic spines and normal behavior

(2012) A.J. Vigers et al.   NEUROSCIENCE

Interactions between estradiol, BDNF and dendritic spines in promoting memory

(2012) V. Luine et al.   NEUROSCIENCE

Insulin-like growth factor 1 (IGF1) and its active peptide (1–3)IGF1 enhance the expression of synaptic markers in neuronal circuits through different cellular mechanisms

(2012) Aiden P. Corvin et al.   NEUROSCIENCE LETTERS

MeCP2 Mutation Results in Compartment-Specific Reductions in Dendritic Branching and Spine Density in Layer 5 Motor Cortical Neurons of YFP-H Mice

(2012) David P. Stuss et al.   PLoS One

Activity-dependent BDNF release and TRPC signaling is impaired in hippocampal neurons of Mecp2 mutant mice

(2012) W. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hippocampal CA1 Pyramidal Neurons ofMecp2Mutant Mice Show a Dendritic Spine Phenotype Only in the Presymptomatic Stage

(2012) Christopher A. Chapleau et al.   NEURAL PLASTICITY

Experimental models of Rett syndrome based on Mecp2 dysfunction

(2011) Gaston Calfa et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Network hyperexcitability in hippocampal slices from Mecp2 mutant mice revealed by voltage-sensitive dye imaging

(2011) Gaston Calfa et al.   JOURNAL OF NEUROPHYSIOLOGY

Dendritic spine pathology in neuropsychiatric disorders

(2011) Peter Penzes et al.   NATURE NEUROSCIENCE

Dendritic Spine Plasticity: New Regulatory Roles of Dynamic Microtubules

(2011) Casper C. Hoogenraad et al.   NEUROSCIENTIST

Adult Neural Function Requires MeCP2

(2011) C. M. McGraw et al.   SCIENCE

The short-time structural plasticity of dendritic spines is altered in a model of Rett syndrome

(2011) Silvia Landi et al.   Scientific Reports

Rapid Estradiol Modulation of Neuronal Connectivity and Its Implications for Disease

(2011) Deepak P. Srivastava et al.   Frontiers in Endocrinology

A Model for Neural Development and Treatment of Rett Syndrome Using Human Induced Pluripotent Stem Cells

(2010) Maria C.N. Marchetto et al.   CELL

Brain-derived neurotrophic factor and the development of structural neuronal connectivity

(2010) Susana Cohen-Cory et al.   Developmental Neurobiology

When cortical development goes wrong: schizophrenia as a neurodevelopmental disease of microcircuits

(2010) Laurence Garey   JOURNAL OF ANATOMY

Small molecule BDNF mimetics activate TrkB signaling and prevent neuronal degeneration in rodents

(2010) Stephen M. Massa et al.   JOURNAL OF CLINICAL INVESTIGATION

Epac2-mediated dendritic spine remodeling: Implications for disease

(2010) Peter Penzes et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Structural dynamics of dendritic spines in memory and cognition

(2010) Haruo Kasai et al.   TRENDS IN NEUROSCIENCES

Dendritic Spine Dynamics

(2009) D. Harshad Bhatt et al.   Annual Review of Physiology

A synaptic trek to autism

(2009) Thomas Bourgeron   CURRENT OPINION IN NEUROBIOLOGY

Widespread changes in dendritic and axonal morphology inMecp2-mutant mouse models of rett syndrome: Evidence for disruption of neuronal networks

(2009) Pavel V. Belichenko et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Modulation of dendritic spine development and plasticity by BDNF and vesicular trafficking: fundamental roles in neurodevelopmental disorders associated with mental retardation and autism

(2009) Christopher A. Chapleau et al.   Journal of Neurodevelopmental Disorders

Dendritic spine pathologies in hippocampal pyramidal neurons from Rett syndrome brain and after expression of Rett-associated MECP2 mutations

(2009) Christopher A. Chapleau et al.   NEUROBIOLOGY OF DISEASE

Bdnf overexpression in hippocampal neurons prevents dendritic atrophy caused by Rett-associated MECP2 mutations

(2009) Jennifer L. Larimore et al.   NEUROBIOLOGY OF DISEASE

The common BDNF polymorphism may be a modifier of disease severity in Rett syndrome

(2009) B. B. Zeev et al.   NEUROLOGY

Partial reversal of Rett Syndrome-like symptoms in MeCP2 mutant mice

(2009) Daniela Tropea et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MeCP2, a Key Contributor to Neurological Disease, Activates and Represses Transcription

(2008) M. Chahrour et al.   SCIENCE

Protein Synthesis and Neurotrophin-Dependent Structural Plasticity of Single Dendritic Spines

(2008) J.-i. Tanaka et al.   SCIENCE

Role of the brain-derived neurotrophic factor at glutamatergic synapses

(2007) A L Carvalho et al.   BRITISH JOURNAL OF PHARMACOLOGY

The actions of BDNF on dendritic spine density and morphology in organotypic slice cultures depend on the presence of serum in culture media

(2007) Christopher A. Chapleau et al.   JOURNAL OF NEUROSCIENCE METHODS