A CRISPR-enabled fluorometric biosensor for the sensitive detection of heparin antidote protamine based on programmable nuclease Cas12a

Functional nucleic acids in glycobiology: A versatile tool in the analysis of disease-related carbohydrates and glycoconjugates

(2022) Furong Zhao et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Molecular reporters for CRISPR/Cas: From design principles to engineering for bioanalytical and diagnostic applications

(2022) Muhammad Sohail et al.   TRAC-TRENDS IN ANALYTICAL CHEMISTRY

Signal-Amplified Detection of the Tumor Biomarker FEN1 Based on Cleavage-Induced Ligation of a Dumbbell DNA Probe and Rolling Circle Amplification

(2021) Bingzhi Li et al.   ANALYTICAL CHEMISTRY

An exonuclease protection and CRISPR/Cas12a integrated biosensor for the turn-on detection of transcription factors in cancer cells

(2021) Bingzhi Li et al.   ANALYTICA CHIMICA ACTA

Advancing sensing technology with CRISPR: From the detection of nucleic acids to a broad range of analytes – A review

(2021) Siying Xie et al.   ANALYTICA CHIMICA ACTA

Simultaneous characterization of insulin HMWP and protamine sulphate in complex formulations through SEC-coupled mass spectrometry

(2021) Koduru Srivatsa et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Recent advances in quantum dots-based biosensors for antibiotic detection

(2021) Rui Ding et al.   Journal of Pharmaceutical Analysis

Sensitive detection of a bacterial pathogen using allosteric probe-initiated catalysis and CRISPR-Cas13a amplification reaction

(2020) Jinjin Shen et al.   Nature Communications

A CRISPR-derived biosensor for the sensitive detection of transcription factors based on the target-induced inhibition of Cas12a activation

(2020) Bingzhi Li et al.   BIOSENSORS & BIOELECTRONICS

TAp63α targeting of Lgr5 mediates colorectal cancer stem cell properties and sulforaphane inhibition

(2020) Yue Chen et al.   Oncogenesis

CRISPR-Cas12a-Based Nucleic Acid Amplification-Free DNA Biosensor via Au Nanoparticle-Assisted Metal-Enhanced Fluorescence and Colorimetric Analysis

(2020) Jin-Ha Choi et al.   NANO LETTERS

CRISPR/Cas Systems towards Next-Generation Biosensing

(2019) Yi Li et al.   TRENDS IN BIOTECHNOLOGY

CRISPR/Cas-Mediated Base Editing: Technical Considerations and Practical Applications

(2019) Kutubuddin A. Molla et al.   TRENDS IN BIOTECHNOLOGY

CRISPR-Cas12a has both cis- and trans-cleavage activities on single-stranded DNA

(2018) Shi-Yuan Li et al.   CELL RESEARCH

Plastics recycling with a difference

(2018) Haritz Sardon et al.   SCIENCE

CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity

(2018) Janice S. Chen et al.   SCIENCE

Multiplexed and portable nucleic acid detection platform with Cas13, Cas12a, and Csm6

(2018) Jonathan S. Gootenberg et al.   SCIENCE

A facile four-armed AIE fluorescent sensor for heparin and protamine

(2018) Yuxia Gao et al.   SENSORS AND ACTUATORS B-CHEMICAL

Programmed DNA destruction by miniature CRISPR-Cas14 enzymes

(2018) Lucas B. Harrington et al.   SCIENCE

Heparin-MPA dual modified CdS quantum dots used as a simple and rapid label-free fluorescent sensor for protamine and hemin detection

(2017) Guimei Guan et al.   MICROCHEMICAL JOURNAL

Nucleic acid detection with CRISPR-Cas13a/C2c2

(2017) Jonathan S. Gootenberg et al.   SCIENCE

CRISPR/Cas9 in Genome Editing and Beyond

(2016) Haifeng Wang et al.   Annual Review of Biochemistry

Hierarchical Self-Assembly of Discrete Organoplatinum(II) Metallacycles with Polysaccharide via Electrostatic Interactions and Their Application for Heparin Detection

(2015) Li-Jun Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

CRISPR-Cas immunity in prokaryotes

(2015) Luciano A. Marraffini   NATURE

A simple fluorescent probe based on a pyrene derivative for rapid detection of protamine and monitoring of trypsin activity

(2015) Baiyang Tang et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

A fluorescence assay for the trace detection of protamine and heparin

(2014) Shu Pang et al.   RSC Advances

Colorimetric and fluorescent detection of protamines with an anionic polythiophene derivative

(2013) Zhiyi Yao et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Application of quality by design elements for the development and optimization of an analytical method for protamine sulfate

(2012) David Awotwe-Otoo et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Polyelectrolyte-Functionalized Gold Nanoparticle Scaffold for the Sensing of Heparin and Protamine in Serum

(2011) Ramendra Sundar Dey et al.   Chemistry-An Asian Journal

Fluorescence turn-on detection of protamine based on aggregation-induced emission enhancement characteristics of 4-(6′-carboxyl)hexyloxysalicylaldehyde azine

(2010) Xiao-tong Chen et al.   ANALYST

Optical sensing of biomedically important polyionic drugs using nano-sized gold particles

(2007) Bikash Kumar Jena et al.   BIOSENSORS & BIOELECTRONICS

Aptamer-based biosensors

(2007) Shiping Song et al.   TRAC-TRENDS IN ANALYTICAL CHEMISTRY