Genetic polymorphism, constitutive expression and tissue localization of Dirofilaria immitis P-glycoprotein 11: a putative marker of macrocyclic lactone resistance

Development of rapid in vitro colorimetric enzymatic activity assay to differentiate macrocyclic lactone susceptible and resistant Dirofilaria immitis isolates

(2022) Emily Curry et al.   VETERINARY PARASITOLOGY

Dirofilaria immitis: Genotyping Randomly Selected European Clinical Samples and USA Laboratory Isolates with Molecular Markers Associated with Macrocyclic Lactone Susceptibility and Resistance

(2022) Emily Curry et al.   Pathogens

Macrocyclic lactone resistance in Dirofilaria immitis: risks for prevention of heartworm disease

(2021) Roger K. Prichard   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Concern for Dirofilaria immitis and Macrocyclic Lactone Loss of Efficacy: Current Situation in the USA and Europe, and Future Scenarios

(2021) Anastasia Diakou et al.   Pathogens

Using population genetics to examine relationships of Dirofilaria immitis based on both macrocyclic lactone-resistance status and geography

(2020) Julie Sanchez et al.   VETERINARY PARASITOLOGY

Clinical validation of molecular markers of macrocyclic lactone resistance in Dirofilaria immitis

(2018) Cristina Ballesteros et al.   International Journal for Parasitology-Drugs and Drug Resistance

WormBase ParaSite − a comprehensive resource for helminth genomics

(2017) Kevin L. Howe et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Energy transduction and alternating access of the mammalian ABC transporter P-glycoprotein

(2017) Brandy Verhalen et al.   NATURE

Efficacy of oral moxidectin against susceptible and resistant isolates of Dirofilaria immitis in dogs

(2017) Tom L. McTier et al.   Parasites & Vectors

Does evaluation of in vitro microfilarial motility reflect the resistance status of Dirofilaria immitis isolates to macrocyclic lactones?

(2017) Mary J. Maclean et al.   Parasites & Vectors

Genetic profiles of ten Dirofilaria immitis isolates susceptible or resistant to macrocyclic lactone heartworm preventives

(2017) Catherine Bourguinat et al.   Parasites & Vectors

Polymorphism in ABC transporter genes of Dirofilaria immitis

(2017) Thangadurai Mani et al.   International Journal for Parasitology-Drugs and Drug Resistance

Acquired Tolerance to Ivermectin and Moxidectin after Drug Selection Pressure in the Nematode Caenorhabditis elegans

(2016) Cécile Ménez et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Interaction of macrocyclic lactones with a Dirofilaria immitis P-glycoprotein

(2016) Thangadurai Mani et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

ABC-B transporter genes in Dirofilaria immitis

(2016) Catherine Bourguinat et al.   International Journal for Parasitology-Drugs and Drug Resistance

WormBase 2016: expanding to enable helminth genomic research

(2015) Kevin L. Howe et al.   NUCLEIC ACIDS RESEARCH

Macrocyclic lactone resistance in Dirofilaria immitis: Failure of heartworm preventives and investigation of genetic markers for resistance

(2015) Catherine Bourguinat et al.   VETERINARY PARASITOLOGY

Transgenically expressed Parascaris P-glycoprotein-11 can modulate ivermectin susceptibility in Caenorhabditis elegans

(2015) I. Jana I. Janssen et al.   International Journal for Parasitology-Drugs and Drug Resistance

Trimmomatic: a flexible trimmer for Illumina sequence data

(2014) Anthony M. Bolger et al.   BIOINFORMATICS

Establishment of macrocyclic lactone resistant Dirofilaria immitis isolates in experimentally infected laboratory dogs

(2014) Cassan N Pulaski et al.   Parasites & Vectors

Protter: interactive protein feature visualization and integration with experimental proteomic data

(2013) Ulrich Omasits et al.   BIOINFORMATICS

Lipid-like properties and pharmacology of the anthelmintic macrocyclic lactones

(2013) Anne Lespine   Expert Opinion on Drug Metabolism & Toxicology

Potential contribution of P-glycoproteins to macrocyclic lactone resistance in the cattle parasitic nematode Cooperia oncophora

(2013) Janina Demeler et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Gene expression analysis of ABC transporters in a resistant Cooperia oncophora isolate following in vivo and in vitro exposure to macrocyclic lactones

(2013) J. DE GRAEF et al.   PARASITOLOGY

Genetic Variants and Increased Expression of Parascaris equorum P-glycoprotein-11 in Populations with Decreased Ivermectin Susceptibility

(2013) I. Jana I. Janssen et al.   PLoS One

The genome of the heartworm, Dirofilaria immitis, reveals drug and vaccine targets

(2012) Christelle Godel et al.   FASEB JOURNAL

Selection of Reliable Reference Genes in Caenorhabditis elegans for Analysis of Nanotoxicity

(2012) Yanqiong Zhang et al.   PLoS One

Genetic polymorphism in Dirofilaria immitis

(2011) Catherine Bourguinat et al.   VETERINARY PARASITOLOGY

Macrocyclic lactone resistance in Dirofilaria immitis

(2011) Catherine Bourguinat et al.   VETERINARY PARASITOLOGY

A spatial and temporal map of C. elegans gene expression

(2010) W. C. Spencer et al.   GENOME RESEARCH

Ivermectin disrupts the function of the excretory-secretory apparatus in microfilariae of Brugia malayi

(2010) Y. Moreno et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fast and accurate short read alignment with Burrows-Wheeler transform

(2009) H. Li et al.   BIOINFORMATICS

Selection and validation of a set of reliable reference genes for quantitative sod gene expression analysis in C. elegans

(2008) David Hoogewijs et al.   BMC MOLECULAR BIOLOGY

Increased expression of ABC transport proteins is associated with ivermectin resistance in the model nematode Caenorhabditis elegans

(2008) Catherine E. James et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

ABC transporter modulation: a strategy to enhance the activity of macrocyclic lactone anthelmintics

(2008) Anne Lespine et al.   TRENDS IN PARASITOLOGY