Cognate microglia–T cell interactions shape the functional regulatory T cell pool in experimental autoimmune encephalomyelitis pathology

Multiple sclerosis: doubling down on MHC

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Interleukin-10 Prevents Pathological Microglia Hyperactivation following Peripheral Endotoxin Challenge

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A Binary Cre Transgenic Approach Dissects Microglia and CNS Border-Associated Macrophages

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Blimp1 Prevents Methylation of Foxp3 and Loss of Regulatory T Cell Identity at Sites of Inflammation

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MARS-seq2.0: an experimental and analytical pipeline for indexed sorting combined with single-cell RNA sequencing

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Circulating T cell-monocyte complexes are markers of immune perturbations

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Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)

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Pathogenic T cell cytokines in multiple sclerosis

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The CNS Immune Landscape from the Viewpoint of a T Cell

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Comparative analysis of CreER transgenic mice for the study of brain macrophages: A case study

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Microglial MHC class II is dispensable for experimental autoimmune encephalomyelitis and cuprizone-induced demyelination

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Re-evaluating microglia expression profiles using RiboTag and cell isolation strategies

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Neuroinflammation: Microglia and T Cells Get Ready to Tango

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The identity and function of microglia in neurodegeneration

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Microglial signatures and their role in health and disease

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Engrafted parenchymal brain macrophages differ from microglia in transcriptome, chromatin landscape and response to challenge

(2018) Anat Shemer et al.   Nature Communications

Multiple sclerosis

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Treg-specific IL-27Rα deletion uncovers a key role for IL-27 in Treg function to control autoimmunity

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IL-27, but not IL-35, inhibits neuroinflammation through modulating GM-CSF expression

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Multiple sclerosis: experimental models and reality

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Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9

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Production of IL-27 in multiple sclerosis lesions by astrocytes and myeloid cells: Modulation of local immune responses

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Unraveling CRISPR-Cas9 genome engineering parameters via a library-on-library approach

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IFN-γ ameliorates autoimmune encephalomyelitis by limiting myelin lipid peroxidation

(2015) Rebecca A. Sosa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Glucocorticoid-Induced Tumour Necrosis Factor Receptor-Related Protein: A Key Marker of Functional Regulatory T Cells

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Tissue-Resident Macrophage Enhancer Landscapes Are Shaped by the Local Microenvironment

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The deubiquitinase activity of A20 is dispensable for NF- B signaling

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Continuous T Cell Receptor Signals Maintain a Functional Regulatory T Cell Pool

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Differential roles of microglia and monocytes in the inflamed central nervous system

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Identifying the Initiating Events of Anti-Listeria Responses Using Mice with Conditional Loss of IFN-  Receptor Subunit 1 (IFNGR1)

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DNA targeting specificity of RNA-guided Cas9 nucleases

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Modeling the heterogeneity of multiple sclerosis in animals

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Fate Mapping Reveals Origins and Dynamics of Monocytes and Tissue Macrophages under Homeostasis

(2012) Simon Yona et al.   IMMUNITY

CD4+FOXP3+ T Regulatory Cells in Human Autoimmunity: More Than a Numbers Game

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Fate mapping of IL-17-producing T cells in inflammatory responses

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Infiltrating monocytes trigger EAE progression, but do not contribute to the resident microglia pool

(2011) Bahareh Ajami et al.   NATURE NEUROSCIENCE

Genetic proof for the transient nature of the Th17 phenotype

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CCR2+Ly-6Chi monocytes are crucial for the effector phase of autoimmunity in the central nervous system

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Effector T cell interactions with meningeal vascular structures in nascent autoimmune CNS lesions

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Cell-type-specific isolation of ribosome-associated mRNA from complex tissues

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