Biotechnology and In Vitro Culture as an Alternative System for Secondary Metabolite Production

Tailoring sensory properties of plant cell cultures for food use

(2022) Ritala Anneli et al.   FOOD RESEARCH INTERNATIONAL

Hairy Root Cultures as a Source of Polyphenolic Antioxidants: Flavonoids, Stilbenoids and Hydrolyzable Tannins

(2022) Janusz Malarz et al.   Plants-Basel

Molecular and Biochemical Mechanisms of Elicitors in Pest Resistance

(2022) Saif ul Malook et al.   Life-Basel

Induction of the Prenylated Stilbenoids Arachidin-1 and Arachidin-3 and Their Semi-Preparative Separation and Purification from Hairy Root Cultures of Peanut (Arachis hypogaea L.)

(2022) Amit Raj Sharma et al.   MOLECULES

Accumulation of volatile constituents in agar and bioreactor shoot cultures of Verbena officinalis L.

(2021) Adam Kokotkiewicz et al.   PLANT CELL TISSUE AND ORGAN CULTURE

Effects of Abiotic Elicitors on Expression and Accumulation of Three Candidate Benzophenanthridine Alkaloids in Cultured Greater Celandine Cells

(2021) Seyed Mohammad Hashemi et al.   MOLECULES

Establishment of a Cell Suspension Culture of Eysenhardtia platycarpa: Phytochemical Screening of Extracts and Evaluation of Antifungal Activity

(2021) Antonio Bernabé-Antonio et al.   Plants-Basel

Enhanced gymnemic acids production in cell suspension cultures of Gymnema sylvestre (Retz.) R.Br. ex Sm. through elicitation

(2021) Ganesan Mahendran et al.   INDUSTRIAL CROPS AND PRODUCTS

Micropropagation of Ginger (Zingiber officinale Roscoe) ‘Bentong’ and Evaluation of Its Secondary Metabolites and Antioxidant Activities Compared with the Conventionally Propagated Plant

(2021) Nisar Ahmad Zahid et al.   Plants-Basel

Shoot Multiplication and Callus Induction of Labisia pumila var. alata as Influenced by Different Plant Growth Regulators Treatments and Its Polyphenolic Activities Compared with the Wild Plant

(2021) Mat Yunus Najhah et al.   MOLECULES

Iron-doped zinc oxide nanoparticles-triggered elicitation of important phenolic compounds in cell cultures of Fagonia indica

(2021) Atta Ullah Khan et al.   PLANT CELL TISSUE AND ORGAN CULTURE

Chitosan elicitation of saponin accumulation in Psammosilene tunicoides hairy roots by modulating antioxidant activity, nitric oxide production and differential gene expression

(2021) Hanhan Qiu et al.   PLANT PHYSIOLOGY AND BIOCHEMISTRY

Moroccan antidiabetic medicinal plants: Ethnobotanical studies, phytochemical bioactive compounds, preclinical investigations, toxicological validations and clinical evidences; challenges, guidance and perspectives for future management of diabetes worldwide

(2021) Abdelhakim Bouyahya et al.   TRENDS IN FOOD SCIENCE & TECHNOLOGY

Production of ginsenoside by Chaetomium sp. and its effect on enhancing the contents of ginsenosides in Panax ginseng adventitious roots

(2021) Xin-dan Xu et al.   BIOCHEMICAL ENGINEERING JOURNAL

Polyurethane Foam Rafts Supported In Vitro Cultures of Rindera graeca Roots for Enhanced Production of Rinderol, Potent Proapoptotic Naphthoquinone Compound

(2021) Mateusz Kawka et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Plant-microbial interaction: The mechanism and the application of microbial elicitor induced secondary metabolites biosynthesis in medicinal plants

(2021) Imane Chamkhi et al.   PLANT PHYSIOLOGY AND BIOCHEMISTRY

Fungal endophytes from medicinal plant Bletilla striata (Thunb.) Reichb. F. promote the host plant growth and phenolic accumulation

(2021) Jianhua Chen et al.   SOUTH AFRICAN JOURNAL OF BOTANY

Synergistic effects of salicylic acid and light stress on bioactive metabolites in basil callus cultures

(2021) Saher Nazir et al.   Biocatalysis and Agricultural Biotechnology

Accumulation of valuable secondary metabolites: phenolic acids and flavonoids in different in vitro systems of shoot cultures of the endangered plant species—Eryngium alpinum L.

(2020) Małgorzata Kikowska et al.   PLANT CELL TISSUE AND ORGAN CULTURE

The effects of ultrasound assisted extraction on yield, antioxidant, anticancer and antimicrobial activity of polyphenol extracts: A review

(2020) Courage Sedem Dzah et al.   Food Bioscience

Chitosan effects on the elevation of essential oils and antioxidant activity of Carum copticum L. seedlings and callus cultures under in vitro salt stress

(2020) Roya Razavizadeh et al.   JOURNAL OF PLANT BIOCHEMISTRY AND BIOTECHNOLOGY

Plant secondary metabolites synthesis and their regulations under biotic and abiotic constraints

(2020) Shubhra Khare et al.   JOURNAL OF PLANT BIOLOGY

Supercritical CO2 extraction of Aloysia gratissima leaves and evaluation of anti-inflammatory activity

(2020) Maryelen A. Souza et al.   JOURNAL OF SUPERCRITICAL FLUIDS

Biosynthesis of rutin changes in Capparis spinosa due to altered expression of its pathway genes under elicitors’ supplementation

(2020) Farzad Kianersi et al.   PLANT CELL TISSUE AND ORGAN CULTURE

Induction of somatic embryogenesis in leaf and root explants of Digitalis lanata Ehrh.: Direct and indirect method

(2020) B.P. Bhusare et al.   SOUTH AFRICAN JOURNAL OF BOTANY

Development of a Direct in vitro Plant Regeneration Protocol From Cannabis sativa L. Seedling Explants: Developmental Morphology of Shoot Regeneration and Ploidy Level of Regenerated Plants

(2020) Alberto Galán-Ávila et al.   Frontiers in Plant Science

Unraveling Plant Natural Chemical Diversity for Drug Discovery Purposes

(2020) Emmanuelle Lautié et al.   Frontiers in Pharmacology

Selection and micropropagation of valuable caper genotypes

(2020) Francesco Sottile et al.   HORTICULTURAL SCIENCE

High-efficiency direct somatic embryogenesis and plant regeneration from leaf base explants of “peperina” (Minthostachys verticillata)

(2020) Valentina Goytia Bertero et al.   IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-PLANT

Ginsenoside synthesis of adventitious roots in Panax ginseng is promoted by fungal suspension homogenate of Alternaria panax and regulated by several signaling molecules

(2020) Yue-Jun Hao et al.   INDUSTRIAL CROPS AND PRODUCTS

Establishment of cell suspension cultures of Ocimum basilicum L. and enhanced production of pharmaceutical active ingredients

(2020) Muhammed Akif Açıkgöz   INDUSTRIAL CROPS AND PRODUCTS

Induction of Callogenesis, Organogenesis, and Embryogenesis in Non-Meristematic Explants of Bleeding Heart and Evaluation of Chemical Diversity of Key Metabolites from Callus

(2020) Dariusz Kulus et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Deciphering the role of stress elicitors on the differential modulation of chalcone synthase gene and subsequent production of secondary metabolites in micropropagated Coelogyne ovalis Lindl., a therapeutically important medicinal orchid

(2020) Nutan Singh et al.   SOUTH AFRICAN JOURNAL OF BOTANY

Enhanced Production of Bryonolic Acid in Trichosanthes cucumerina L. (Thai Cultivar) Cell Cultures by Elicitors and Their Biological Activities

(2020) Pornpatsorn Lertphadungkit et al.   Plants-Basel

Effects of sorbitol on the production of phenolic compounds and terpenoids in the cell suspension cultures of Ocimum basilicum L.

(2020) Muhammed A. Açıkgöz   BIOLOGIA

Isolation and optimization of plumbagin production in root callus of Plumbago zeylanica L. augmented with chitosan and yeast extract

(2020) Tikkam Singh et al.   INDUSTRIAL CROPS AND PRODUCTS

Elicitor-Induced Production of Biomass and Pharmaceutical Phenolic Compounds in Cell Suspension Culture of Date Palm (Phoenix dactylifera L.)

(2020) Jameel Mohammed Al-Khayri et al.   MOLECULES

Establishment and triterpenoid production of Ocimum basilicum cambial meristematic cells

(2020) Alexander Mehring et al.   PLANT CELL TISSUE AND ORGAN CULTURE

In Vitro Responses of Plant Growth Factors on Growth, Yield, Phenolics Content and Antioxidant Activities of Clinacanthus nutans (Sabah Snake Grass)

(2020) Zainol Haida et al.   Plants-Basel

In vitro propagation of Salvia sclarea L. by meta-Topolin, and assessment of genetic stability and secondary metabolite profiling of micropropagated plants

(2020) Semiha Erişen et al.   INDUSTRIAL CROPS AND PRODUCTS

Enhanced bioactive compounds composition in Lavandula officinalis in-vitro plantlets using NaCl and Moringa oleifera, Aloe vera and Spirulina platensis extracts

(2020) Fadia El Sherif et al.   INDUSTRIAL CROPS AND PRODUCTS

In vitro cultivation of tansy (Tanacetum vulgare L.): a tool for the production of potent pharmaceutical agents

(2020) Nina Devrnja et al.   PROTOPLASMA

Induction, Multiplication, and Evaluation of Antioxidant Activity of Polyalthia bullata Callus, a Woody Medicinal Plant

(2020) Munirah Adibah Kamarul Zaman et al.   Plants-Basel

Silver nanoparticles elicited in vitro callus cultures for accumulation of biomass and secondary metabolites in Caralluma tuberculata

(2019) Amir Ali et al.   Artificial Cells Nanomedicine and Biotechnology

In vitro propagation of a carvacrol-producing type of Lippia origanoides Kunth: A promising oregano-like herb

(2019) Caroline V.V. Castilho et al.   INDUSTRIAL CROPS AND PRODUCTS

Chemical characterization of leaves and calli extracts of Rosmarinus officinalis by UHPLC‐MS

(2019) Martha Berenice Pérez‐Mendoza et al.   ELECTROPHORESIS

Elicitation: A biotechnological tool for enhanced production of secondary metabolites in hairy root cultures

(2019) Mihir Halder et al.   ENGINEERING IN LIFE SCIENCES

Antidiabetic Potential of Medicinal Plants and Their Active Components

(2019) Salehi et al.   Biomolecules

Profile of secondary metabolites and genetic stability analysis in new lines of Echinacea purpurea (L.) Moench micropropagated via somatic embryogenesis

(2019) Justyna Lema-Rumińska et al.   INDUSTRIAL CROPS AND PRODUCTS

Impact of operating parameters on values of a volumetric mass transfer coefficient in a single-use bioreactor with wave-induced agitation

(2018) Maciej Pilarek et al.   CHEMICAL ENGINEERING RESEARCH & DESIGN

Effects of plant growth regulators, different culture media and strength MS on production of volatile fraction composition in shoot cultures of Ocimum basilicum

(2018) Lucila Elizabeth Fragoso Monfort et al.   INDUSTRIAL CROPS AND PRODUCTS

Influence of light quality on growth, secondary metabolites production and antioxidant activity in callus culture of Rhodiola imbricata Edgew

(2018) Sahil Kapoor et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

In vitro plant tissue culture: means for production of biological active compounds

(2018) Claudia A. Espinosa-Leal et al.   PLANTA

A critical analysis of extraction techniques used for botanicals: Trends, priorities, industrial uses and optimization strategies

(2018) Tarun Belwal et al.   TRAC-TRENDS IN ANALYTICAL CHEMISTRY

Techniques for extraction and isolation of natural products: a comprehensive review

(2018) Qing-Wen Zhang et al.   Chinese Medicine

Production of Plant Secondary Metabolites: Examples, Tips and Suggestions for Biotechnologists

(2018) Gea Guerriero et al.   Genes

Plant cell culture technology in the cosmetics and food industries: current state and future trends

(2018) Regine Eibl et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

An overview of cosmeceutically relevant plant extracts and strategies for extraction of plant-based bioactive compounds

(2018) Nur Azzanizawaty Yahya et al.   FOOD AND BIOPRODUCTS PROCESSING

Depsidone Derivatives and a Cyclopeptide Produced by Marine Fungus Aspergillus unguis under Chemical Induction and by Its Plasma Induced Mutant

(2018) Wen-Cong Yang et al.   MOLECULES

Micropropagation of the Mongolian medicinal plant Zygophyllum potaninii via somatic embryogenesis

(2018) Gun-Aajav Bayarmaa et al.   Plant Biotechnology Reports

Uprising the antioxidant power of Argania spinosa L. callus through abiotic elicitation

(2018) Mouna Lamaoui et al.   COMPTES RENDUS BIOLOGIES

Bioreactor-based advances in plant tissue and cell culture: challenges and prospects

(2018) Alireza Valdiani et al.   CRITICAL REVIEWS IN BIOTECHNOLOGY

Comparison of elicitor-based effects on metabolic responses of Taxus × media hairy roots in perfluorodecalin-supported two-phase culture system

(2018) K. Sykłowska-Baranek et al.   PLANT CELL REPORTS

Biotechnology Applications of Plant Callus Cultures

(2018) Thomas Efferth   Engineering

Effects of chitosan and salicylic acid on the production of pharmacologically attractive secondary metabolites in callus cultures of Fagonia indica

(2018) Taimoor Khan et al.   INDUSTRIAL CROPS AND PRODUCTS

Supercritical CO 2 extraction of essential oil from Algerian Argan ( Argania spinosa L.) seeds and yield optimization

(2017) Ismahane Haloui et al.   INTERNATIONAL JOURNAL OF HYDROGEN ENERGY

Effect of ultrasonic waves on crocin and safranal content and expression of their controlling genes in suspension culture of saffron (Crocus sativus L.)

(2017) Tofigh Taherkhani et al.   NATURAL PRODUCT RESEARCH

Secondary metabolism of pharmaceuticals in the plant in vitro cultures: strategies, approaches, and limitations to achieving higher yield

(2017) Tasiu Isah et al.   PLANT CELL TISSUE AND ORGAN CULTURE

Optimization of the extraction process of polyphenols from Thymus serpyllum L. herb using maceration, heat- and ultrasound-assisted techniques

(2017) Aleksandra A. Jovanović et al.   SEPARATION AND PURIFICATION TECHNOLOGY

In vitro propagation, genetic stability, and secondary metabolite analysis of wild lavender (Lavandula coronopifolia Poir.)

(2017) Wesam Al Khateeb et al.   Horticulture Environment and Biotechnology

Plant cell culture strategies for the production of natural products

(2016) Marisol Ochoa-Villarreal et al.   BMB Reports

Chemical Polymorphism ofOriganum compactumGrown in All Natural Habitats in Morocco

(2016) Kaoutar Aboukhalid et al.   CHEMISTRY & BIODIVERSITY

Production of rosmarinic acid and salvianolic acid B from callus culture of Salvia miltiorrhiza with cytotoxicity towards acute lymphoblastic leukemia cells

(2016) Ching-Fen Wu et al.   FOOD CHEMISTRY

Fungal elicitors enhance ginsenosides biosynthesis, expression of functional genes as well as signal molecules accumulation in adventitious roots of Panax ginseng C. A. Mey

(2016) Jinxin Li et al.   JOURNAL OF BIOTECHNOLOGY

Natural Products as Sources of New Drugs from 1981 to 2014

(2016) David J. Newman et al.   JOURNAL OF NATURAL PRODUCTS

Light-induced biochemical variations in secondary metabolite production and antioxidant activity in callus cultures of Stevia rebaudiana (Bert)

(2016) Naveed Ahmad et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

Elicitation, an Effective Strategy for the Biotechnological Production of Bioactive High-Added Value Compounds in Plant Cell Factories

(2016) Karla Ramirez-Estrada et al.   MOLECULES

Chemical elicitors versus secondary metabolite production in vitro using plant cell, tissue and organ cultures: recent trends and a sky eye view appraisal

(2016) Charu Chandra Giri et al.   PLANT CELL TISSUE AND ORGAN CULTURE

Cheminformatic comparison of approved drugs from natural product versus synthetic origins

(2015) Christopher F. Stratton et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Discovery and resupply of pharmacologically active plant-derived natural products: A review

(2015) Atanas G. Atanasov et al.   BIOTECHNOLOGY ADVANCES

Micropropagation of Anacyclus pyrethrum and chemical profiling of the regenerated plants for pellitorine, the active principle

(2015) Deepak K. Singh et al.   PLANT CELL TISSUE AND ORGAN CULTURE

Production and gene expression of morphinan alkaloids in hairy root culture of Papaver orientale L. using abiotic elicitors

(2015) Seyed Mohammad Hashemi et al.   PLANT CELL TISSUE AND ORGAN CULTURE

Liquid Perfluorodecalin Application for In Situ Extraction and Enhanced Naphthoquinones Production in Arnebia euchroma Cell Suspension Cultures

(2014) Katarzyna Sykłowska-Baranek et al.   APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

Medicinal plant cell suspension cultures: pharmaceutical applications and high-yielding strategies for the desired secondary metabolites

(2014) Wei Yue et al.   CRITICAL REVIEWS IN BIOTECHNOLOGY

Gymnemic acid enhancement in the suspension cultures of Gymnema sylvestre by using the signaling molecules—methyl jasmonate and salicylic acid

(2014) Bhuvaneswari Chodisetti et al.   IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-PLANT

Enhanced bacoside production in shoot cultures ofBacopa monnieriunder the influence of abiotic elicitors

(2014) Munish Sharma et al.   NATURAL PRODUCT RESEARCH

Production of secondary metabolites from cell and organ cultures: strategies and approaches for biomass improvement and metabolite accumulation

(2014) Hosakatte Niranjana Murthy et al.   PLANT CELL TISSUE AND ORGAN CULTURE

Techniques for extraction of bioactive compounds from plant materials: A review

(2013) J. Azmir et al.   JOURNAL OF FOOD ENGINEERING

Sustainable Medicines and Global Health Care

(2011) Geoffrey Cordell   PLANTA MEDICA

Production of adventitious roots and secondary metabolites by Hypericum perforatum L. in a bioreactor

(2010) Xi-Hua Cui et al.   BIORESOURCE TECHNOLOGY

Bioprocessing of plant cell cultures for mass production of targeted compounds

(2009) Milen I. Georgiev et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Elicitor-induced accumulation of stilbenes in cell suspension cultures of Cayratia trifolia (L.) Domin

(2009) Chetana Roat et al.   Plant Biotechnology Reports

Inoculum size and auxin concentration influence the growth of adventitious roots and accumulation of ginsenosides in suspension cultures of ginseng (Panax ginseng C.A. Meyer)

(2008) C. S. Jeong et al.   ACTA PHYSIOLOGIAE PLANTARUM

Pharmaceutically Active Natural Product Synthesis and Supply via Plant Cell Culture Technology

(2008) Martin E. Kolewe et al.   MOLECULAR PHARMACEUTICS