Multiplex G Protein–Coupled Receptor Screen Reveals Reliably Acting Agonists and a Gq-Phospholipase C Coupling Mode of GPR30/GPER1

Allosteric coupling and biased agonism in G protein‐coupled receptors

(2021) Andreas Bock et al.   FEBS Journal

Ligand-Independent G Protein–Coupled Estrogen Receptor/G Protein–Coupled Receptor 30 Activity: Lack of Receptor-Dependent Effects of G-1 and 17β-Estradiol

(2021) Julia Tutzauer et al.   MOLECULAR PHARMACOLOGY

Proteinase-Activated Receptor 4 Activation Triggers Cell Membrane Blebbing through RhoA and β-Arrestin

(2020) Christina M.G. Vanderboor et al.   MOLECULAR PHARMACOLOGY

Heterotrimeric G Protein Subunit Gαq Is a Master Switch for Gβγ-Mediated Calcium Mobilization by Gi-Coupled GPCRs

(2020) Eva Marie Pfeil et al.   MOLECULAR CELL

G-Protein-Coupled Estrogen Receptor (GPER)-Specific Agonist G1 Induces ER Stress Leading to Cell Death in MCF-7 Cells

(2019) Diep-Khanh Ho Vo et al.   Biomolecules

Novel approaches leading towards peptide GPCR de‐orphanisation

(2019) Alexander S. Hauser et al.   BRITISH JOURNAL OF PHARMACOLOGY

The G protein-coupled receptors deorphanization landscape

(2018) Céline Laschet et al.   BIOCHEMICAL PHARMACOLOGY

G Protein-Coupled Receptors as Targets for Approved Drugs: How Many Targets and How Many Drugs?

(2018) Krishna Sriram et al.   MOLECULAR PHARMACOLOGY

Angiotensin II Signal Transduction: An Update on Mechanisms of Physiology and Pathophysiology

(2018) Steven J. Forrester et al.   PHYSIOLOGICAL REVIEWS

Discovery and characterization of a positive allosteric modulator of transient receptor potential canonical 6 (TRPC6) channels

(2018) S. Häfner et al.   CELL CALCIUM

Macromolecular Modelling and Docking Simulations for the Discovery of Selective GPER Ligands

(2015) Camillo Rosano et al.   AAPS Journal

Fourth-Generation Epac-Based FRET Sensors for cAMP Feature Exceptional Brightness, Photostability and Dynamic Range: Characterization of Dedicated Sensors for FLIM, for Ratiometry and with High Affinity

(2015) Jeffrey Klarenbeek et al.   PLoS One

G protein-coupled Receptor 30 (GPR30) Forms a Plasma Membrane Complex with Membrane-associated Guanylate Kinases (MAGUKs) and Protein Kinase A-anchoring Protein 5 (AKAP5) That Constitutively Inhibits cAMP Production

(2014) Stefan Broselid et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

G-protein-coupled receptor signaling and polarized actin dynamics drive cell-in-cell invasion

(2014) Vladimir Purvanov et al.   eLife

Direct, Differential Effects of Tamoxifen, 4-Hydroxytamoxifen, and Raloxifene on Cardiac Myocyte Contractility and Calcium Handling

(2013) Michelle L. Asp et al.   PLoS One

The ligand specificity of the G-protein-coupled receptor GPR34

(2012) Lars Ritscher et al.   BIOCHEMICAL JOURNAL

The G Protein-Coupled Receptor GPR30 Inhibits Proliferation of Estrogen Receptor-Positive Breast Cancer Cells

(2010) E. A. Ariazi et al.   CANCER RESEARCH

Stimulating the GPR30 Estrogen Receptor with a Novel Tamoxifen Analogue Activates SF-1 and Promotes Endometrial Cell Proliferation

(2009) Benjamin C. Lin et al.   CANCER RESEARCH

G Protein-Coupled Receptor 30 Localizes to the Endoplasmic Reticulum and Is Not Activated by Estradiol

(2008) Christiane Otto et al.   ENDOCRINOLOGY

Expression Pattern of G Protein-Coupled Receptor 30 in LacZ Reporter Mice

(2008) Jörg Isensee et al.   ENDOCRINOLOGY

Deletion of the G Protein-Coupled Receptor 30 Impairs Glucose Tolerance, Reduces Bone Growth, Increases Blood Pressure, and Eliminates Estradiol-Stimulated Insulin Release in Female Mice

(2008) Ulrika E. A. Mårtensson et al.   ENDOCRINOLOGY

A short history of blebbing

(2008) G.T. CHARRAS   JOURNAL OF MICROSCOPY