Reduction of anaerobic glycolysis contributes to angiotensin II-induced podocyte injury with foot process effacement

Rapamycin attenuated podocyte apoptosis via upregulation of nestin in Ang II-induced podocyte injury

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Regenerating glomerular metabolism and function by podocyte pyruvate kinase M2 in diabetic nephropathy

(2022) Jialin Fu et al.   JCI Insight

Non-canonical Wnt/calcium signaling is protective against podocyte injury and glomerulosclerosis

(2022) Dong Zhou et al.   KIDNEY INTERNATIONAL

Transition of acute kidney injury to chronic kidney disease: role of metabolic reprogramming

(2022) Zijing Zhu et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Loss of CLDN5 in podocytes deregulates WIF1 to activate WNT signaling and contributes to kidney disease

(2022) Hui Sun et al.   Nature Communications

Fueling the cytoskeleton – links between cell metabolism and actin remodeling

(2021) Gillian DeWane et al.   JOURNAL OF CELL SCIENCE

Calpastatin prevents Angiotensin II-mediated podocyte injury through maintenance of autophagy

(2021) Imane Bensaada et al.   KIDNEY INTERNATIONAL

Podocyte Autophagy in Homeostasis and Disease

(2021) Qisheng Lin et al.   Journal of Clinical Medicine

Targeting Pyruvate Kinase M2 Phosphorylation Reverses Aggressive Cancer Phenotypes

(2021) Maria Apostolidi et al.   CANCER RESEARCH

The role of metabolic reprogramming in tubular epithelial cells during the progression of acute kidney injury

(2021) Zhenzhen Li et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Mitoquinone Protects Podocytes from Angiotensin II-Induced Mitochondrial Dysfunction and Injury via the Keap1-Nrf2 Signaling Pathway

(2021) Zijing Zhu et al.   Oxidative Medicine and Cellular Longevity

Dephosphorylation of AMP-activated protein kinase exacerbates ischemia/reperfusion-induced acute kidney injury via mitochondrial dysfunction

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Management of Diabetes Mellitus in Patients With CKD: Core Curriculum 2022

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Sodium–glucose cotransporter 2 inhibition suppresses HIF-1α-mediated metabolic switch from lipid oxidation to glycolysis in kidney tubule cells of diabetic mice

(2020) Ting Cai et al.   Cell Death & Disease

Role of pyruvate kinase M2-mediated metabolic reprogramming during podocyte differentiation

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A RECIPROCAL REGULATION OF SPERMIDINE AND AUTOPHAGY IN PODOCYTES MAINTAINS THE FILTRATION BARRIER

(2020) Wei Liang et al.   KIDNEY INTERNATIONAL

Stopping Renin-Angiotensin System Inhibitors in Patients with Advanced CKD and Risk of Adverse Outcomes: A Nationwide Study

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Targeting Energy Pathways in Kidney Disease: The Roles of Sirtuins, AMPK, and PGC1α

(2020) Amanda J. Clark et al.   KIDNEY INTERNATIONAL

Characterization of Glycolytic Enzymes and Pyruvate Kinase M2 in Type 1 and 2 Diabetic Nephropathy

(2019) Daniel Gordin et al.   DIABETES CARE

Anaerobic Glycolysis Maintains the Glomerular Filtration Barrier Independent of Mitochondrial Metabolism and Dynamics

(2019) Paul T. Brinkkoetter et al.   Cell Reports

Metabolic rewiring of the hypertensive kidney

(2019) Markus M. Rinschen et al.   Science Signaling

Mitochondrial dysfunction in diabetic kidney disease

(2018) Josephine M. Forbes et al.   Nature Reviews Nephrology

Mitochondria at the neuronal presynapse in health and disease

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The intriguing nature of dorsal root ganglion neurons: linking structure with polarity and function

(2018) Ana Isabel Nascimento et al.   PROGRESS IN NEUROBIOLOGY

Role of c-Abl and nephrin in podocyte cytoskeletal remodeling induced by angiotensin II

(2018) Yiqiong Ma et al.   Cell Death & Disease

Pyruvate kinase M2 activation may protect against the progression of diabetic glomerular pathology and mitochondrial dysfunction

(2017) Weier Qi et al.   NATURE MEDICINE

Inhibition of the Glycolytic Activator PFKFB3 in Endothelium Induces Tumor Vessel Normalization, Impairs Metastasis, and Improves Chemotherapy

(2016) Anna Rita Cantelmo et al.   CANCER CELL

Podocyte injury and its consequences

(2016) Michio Nagata   KIDNEY INTERNATIONAL

Angiotensin II down-regulates nephrin–Akt signaling and induces podocyte injury: role of c-Abl

(2016) Qian Yang et al.   MOLECULAR BIOLOGY OF THE CELL

The Warburg Effect: How Does it Benefit Cancer Cells?

(2016) Maria V. Liberti et al.   TRENDS IN BIOCHEMICAL SCIENCES

WHAMM Directs the Arp2/3 Complex to the ER for Autophagosome Biogenesis through an Actin Comet Tail Mechanism

(2015) David J. Kast et al.   CURRENT BIOLOGY

Defective fatty acid oxidation in renal tubular epithelial cells has a key role in kidney fibrosis development

(2014) Hyun Mi Kang et al.   NATURE MEDICINE

Tumor glycolysis as a target for cancer therapy: progress and prospects

(2013) Shanmugasundaram Ganapathy-Kanniappan et al.   Molecular Cancer

Defective glucose metabolism in polycystic kidney disease identifies a new therapeutic strategy

(2013) Isaline Rowe et al.   NATURE MEDICINE

A New Era of Podocyte-Targeted Therapy for Proteinuric Kidney Disease

(2013) Börje Haraldsson   NEW ENGLAND JOURNAL OF MEDICINE

Autophagy can repair endoplasmic reticulum stress damage of the passive Heymann nephritis model as revealed by proteomics analysis

(2012) Liyuan Wang et al.   Journal of Proteomics

Aerobic Glycolysis: Meeting the Metabolic Requirements of Cell Proliferation

(2011) Sophia Y. Lunt et al.   Annual Review of Cell and Developmental Biology

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

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