Inhibition of interaction between ROCK1 and Rubicon restores autophagy in endothelial cells and attenuates brain injury after prolonged ischemia

High-salt diet downregulates TREM2 expression and blunts efferocytosis of macrophages after acute ischemic stroke

(2021) Mengyan Hu et al.   Journal of Neuroinflammation

Role of the neurovascular unit in the process of cerebral ischemic injury

(2020) Yu Zhao et al.   PHARMACOLOGICAL RESEARCH

Podocyte EGFR Inhibits Autophagy Through Upregulation of Rubicon in Type 2 Diabetic Nephropathy

(2020) Yan Li et al.   DIABETES

Functional Dynamics of Neutrophils After Ischemic Stroke

(2019) Wei Cai et al.   Translational Stroke Research

LC3-positive structures are prominent in autophagy-deficient cells

(2019) Gautam Runwal et al.   Scientific Reports

All trans-retinoic acid protects against acute ischemic stroke by modulating neutrophil functions through STAT1 signaling

(2019) Wei Cai et al.   Journal of Neuroinflammation

Role of Autophagy in Endothelial Damage and Blood–Brain Barrier Disruption in Ischemic Stroke

(2018) Kyeong-A Kim et al.   STROKE

Disruption of ROCK1 gene restores autophagic flux and mitigates doxorubicin-induced cardiotoxicity

(2018) Jianjian Shi et al.   Oncotarget

Current advances in ischemic stroke research and therapies

(2018) Derek Barthels et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Distinct and complementary functions of rho kinase isoforms ROCK1 and ROCK2 in prefrontal cortex structural plasticity

(2018) Kelsey M. Greathouse et al.   Brain Structure & Function

Inhibition of calcium/calmodulin-dependent protein kinase kinase (CaMKK) exacerbates impairment of endothelial cell and blood-brain barrier after stroke

(2018) Ping Sun et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Reperfusion Changes After Stroke and Practical Approaches for Neuroprotection

(2018) Jae H. Choi et al.   NEUROIMAGING CLINICS OF NORTH AMERICA

Rubicon: LC3-associated phagocytosis and beyond

(2017) Sing-Wai Wong et al.   FEBS Journal

NADPH Oxidase-Related Pathophysiology in Experimental Models of Stroke

(2017) Hiroshi Yao et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Autophagy is required for endothelial cell alignment and atheroprotection under physiological blood flow

(2017) Anne-Clemence Vion et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rubicon inhibits autophagy and accelerates hepatocyte apoptosis and lipid accumulation in nonalcoholic fatty liver disease in mice

(2016) Satoshi Tanaka et al.   HEPATOLOGY

Dynamic changes in neuronal autophagy and apoptosis in the ischemic penumbra following permanent ischemic stroke

(2016) Peng-yue Zhang et al.   Neural Regeneration Research

MicroRNA-9 Mediates the Cell Apoptosis by Targeting Bcl2l11 in Ischemic Stroke

(2015) Na Wei et al.   MOLECULAR NEUROBIOLOGY

Molecular characterization of LC3-associated phagocytosis reveals distinct roles for Rubicon, NOX2 and autophagy proteins

(2015) Jennifer Martinez et al.   NATURE CELL BIOLOGY

Metformin attenuates blood-brain barrier disruption in mice following middle cerebral artery occlusion

(2014) Yanqun Liu et al.   Journal of Neuroinflammation

Modulation of Mitochondrial Function and Autophagy Mediates Carnosine Neuroprotection Against Ischemic Brain Damage

(2014) Seung-Hoon Baek et al.   STROKE

Evaluation of the Protective Potential of Brain Microvascular Endothelial Cell Autophagy on Blood–Brain Barrier Integrity During Experimental Cerebral Ischemia–Reperfusion Injury

(2014) Haiying Li et al.   Translational Stroke Research

Inhibition of Calcium/Calmodulin-Dependent Protein Kinase Kinase β and Calcium/Calmodulin-Dependent Protein Kinase IV Is Detrimental in Cerebral Ischemia

(2013) Louise D. McCullough et al.   STROKE

Identification of ROCK1 kinase as a critical regulator of Beclin1-mediated autophagy during metabolic stress

(2013) Aditi U. Gurkar et al.   Nature Communications

Matrix Metalloproteinases and Blood-Brain Barrier Disruption in Acute Ischemic Stroke

(2013) Shaheen E. Lakhan et al.   Frontiers in Neurology

Regulation of autophagosome formation by Rho kinase

(2012) Andrzej Mleczak et al.   CELLULAR SIGNALLING

Pathophysiology of the Neurovascular Unit: Disease Cause or Consequence?

(2012) Danica B Stanimirovic et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Charting the course across the blood-brain barrier

(2010) David Nathanson et al.   JOURNAL OF CLINICAL INVESTIGATION

Cerebral ischemia induces micro vascular pro-inflammatory cytokine expression via the MEK/ERK pathway

(2010) Aida Maddahi et al.   Journal of Neuroinflammation

Mitochondrial and apoptotic neuronal death signaling pathways in cerebral ischemia

(2009) Kuniyasu Niizuma et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE