Autophagy is required for endothelial cell alignment and atheroprotection under physiological blood flow

The Aging Cardiovascular System

(2017) Francesco Paneni et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

(2016) Daniel J Klionsky et al.   Autophagy

Laminar Shear Stress Promotes Vascular Endothelial Cell Autophagy Through Upregulation with Rab4

(2016) Pingbo Yao et al.   DNA AND CELL BIOLOGY

Primary-cilium-dependent autophagy controls epithelial cell volume in response to fluid flow

(2016) Idil Orhon et al.   NATURE CELL BIOLOGY

Intact endothelial autophagy is required to maintain vascular lipid homeostasis

(2015) Kumiko Torisu et al.   AGING CELL

Disturbed Flow Induces Autophagy, but Impairs Autophagic Flux to Perturb Mitochondrial Homeostasis

(2015) Rongsong Li et al.   ANTIOXIDANTS & REDOX SIGNALING

Defective autophagy in vascular smooth muscle cells accelerates senescence and promotes neointima formation and atherogenesis

(2015) Mandy OJ Grootaert et al.   Autophagy

Molecular Mechanisms of Autophagy in the Cardiovascular System

(2015) D. Gatica et al.   CIRCULATION RESEARCH

Autophagy in Vascular Disease

(2015) G. R. Y. De Meyer et al.   CIRCULATION RESEARCH

Untangling Autophagy Measurements: All Fluxed Up

(2015) R. A. Gottlieb et al.   CIRCULATION RESEARCH

Hemodynamic shear stress modulates endothelial cell autophagy: Role of LOX-1

(2015) Zufeng Ding et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Brief Report: Oxidative Stress Mediates Cardiomyocyte Apoptosis in a Human Model of Danon Disease and Heart Failure

(2015) Sherin I. Hashem et al.   STEM CELLS

Coronary Artery Axial Plaque Stress and its Relationship With Lesion Geometry

(2015) Gilwoo Choi et al.   JACC-Cardiovascular Imaging

Shear stress regulates endothelial cell autophagy via redox regulation and Sirt1 expression

(2015) J Liu et al.   Cell Death & Disease

Autophagy Regulates Vascular Endothelial Cell eNOS and ET-1 Expression Induced by Laminar Shear Stress in an Ex Vivo Perfused System

(2014) Fengxia Guo et al.   ANNALS OF BIOMEDICAL ENGINEERING

Disturbed Flow Promotes Endothelial Senescence via a p53-Dependent Pathway

(2014) Christina M. Warboys et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Laminar shear stress regulates mitochondrial dynamics, bioenergetics responses and PRX3 activation in endothelial cells

(2014) Rosa Bretón-Romero et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Impairment of autophagy in endothelial cells prevents shear-stress-induced increases in nitric oxide bioavailability

(2014) Leena P. Bharath et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Autophagy and regulation of cilia function and assembly

(2014) I Orhon et al.   CELL DEATH AND DIFFERENTIATION

Endothelial Cell Sensing of Flow Direction

(2013) Chong Wang et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Mechanical regulation of cancer cell apoptosis and autophagy: Roles of bone morphogenetic protein receptor, Smad1/5, and p38 MAPK

(2013) Sheng-Chieh Lien et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The atherosusceptible endothelium: endothelial phenotypes in complex haemodynamic shear stress regions in vivo

(2013) Peter F. Davies et al.   CARDIOVASCULAR RESEARCH

Autophagy in Human Health and Disease

(2013)   NEW ENGLAND JOURNAL OF MEDICINE

α1AMP-Activated Protein Kinase Mediates Vascular Protective Effects of Exercise

(2012) Swenja Kröller-Schön et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Autophagy proteins LC3B, ATG5 and ATG12 participate in quality control after mitochondrial damage and influence lifespan

(2012) Sören Mai et al.   Autophagy

Vascular endothelium, hemodynamics, and the pathobiology of atherosclerosis

(2012) Michael A. Gimbrone et al.   CARDIOVASCULAR PATHOLOGY

Autophagy Links Inflammasomes to Atherosclerotic Progression

(2012) Babak Razani et al.   Cell Metabolism

Macrophage Autophagy Plays a Protective Role in Advanced Atherosclerosis

(2012) Xianghai Liao et al.   Cell Metabolism

Cyclin-Dependent Kinase 5–Mediated Hyperphosphorylation of Sirtuin-1 Contributes to the Development of Endothelial Senescence and Atherosclerosis

(2012) Bo Bai et al.   CIRCULATION

Translational evidence that impaired autophagy contributes to arterial ageing

(2012) Thomas J. LaRocca et al.   JOURNAL OF PHYSIOLOGY-LONDON

Primary cilia as biomechanical sensors in regulating endothelial function

(2011) Anastasia D. Egorova et al.   DIFFERENTIATION

Effects of Disturbed Flow on Vascular Endothelium: Pathophysiological Basis and Clinical Perspectives

(2011) Jeng-Jiann Chiu et al.   PHYSIOLOGICAL REVIEWS

A novel quantitative flow cytometry-based assay for autophagy

(2010) Kai Er Eng et al.   Autophagy

VE-cadherin expression allows identification of a new class of hematopoietic stem cells within human embryonic liver

(2010) E. Oberlin et al.   BLOOD

Shear Stress Regulates Angiotensin Type 1 Receptor Expression in Endothelial Cells

(2009) Bhama Ramkhelawon et al.   CIRCULATION RESEARCH

Obesity Increases Vascular Senescence and Susceptibility to Ischemic Injury Through Chronic Activation of Akt and mTOR

(2009) C.-Y. Wang et al.   Science Signaling

Mechanotransduction in vascular physiology and atherogenesis

(2008) Cornelia Hahn et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY