Glioma diagnosis and therapy: Current challenges and nanomaterial-based solutions

RNA cancer nanomedicine: nanotechnology-mediated RNA therapy

(2022) Bijan Emiliano Ferdows et al.   Nanoscale

Synthetic mRNA-based gene therapy for glioblastoma: TRAIL mRNA synergistically enhance PTEN mRNA-based therapy

(2022) Xiangjun Tang et al.   Molecular Therapy-Oncolytics

Ultrasmall iron oxide nanoparticles cause significant toxicity by specifically inducing acute oxidative stress to multiple organs

(2022) Lin Wu et al.   Particle and Fibre Toxicology

Targeted delivery of a STING agonist to brain tumors using bioengineered protein nanoparticles for enhanced immunotherapy

(2022) Bin Wang et al.   Bioactive Materials

A Biomimetic Drug Delivery System by Integrating Grapefruit Extracellular Vesicles and Doxorubicin-Loaded Heparin-Based Nanoparticles for Glioma Therapy

(2021) Wenbo Niu et al.   NANO LETTERS

Long-Term Near-Infrared Signal Tracking of the Therapeutic Changes of Glioblastoma Cells in Brain Tissue with Ultrasound-Guided Persistent Luminescent Nanocomposites

(2021) Chiao-Ling Cheng et al.   ACS Applied Materials & Interfaces

mRNA vaccine for cancer immunotherapy

(2021) Lei Miao et al.   Molecular Cancer

Exosome‐Coated 10 B Carbon Dots for Precise Boron Neutron Capture Therapy in a Mouse Model of Glioma In Situ

(2021) Juan Li et al.   ADVANCED FUNCTIONAL MATERIALS

Targeting RTK-PI3K-mTOR Axis in Gliomas: An Update

(2021) Mayra Colardo et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Magnetite nanoparticles: Synthesis methods – A comparative review

(2021) Adelina-Gabriela Niculescu et al.   METHODS

Reactive Oxygen Species Responsive Polymers for Drug Delivery Systems

(2021) Fengxiang Gao et al.   Frontiers in Chemistry

An Advanced In Situ Magnetic Resonance Imaging and Ultrasonic Theranostics Nanocomposite Platform: Crossing the Blood–Brain Barrier and Improving the Suppression of Glioblastoma Using Iron-Platinum Nanoparticles in Nanobubbles

(2021) Ming-Hsien Chan et al.   ACS Applied Materials & Interfaces

Biodegradable Polymeric Nanoparticles Containing an Immune Checkpoint Inhibitor (aPDL1) to Locally Induce Immune Responses in the Central Nervous System

(2021) Ming Zhang et al.   ADVANCED FUNCTIONAL MATERIALS

A Noninvasive Gut‐to‐Brain Oral Drug Delivery System for Treating Brain Tumors

(2021) Yang‐Bao Miao et al.   ADVANCED MATERIALS

Exosomal circEPB41L2 serves as a sponge for miR‐21‐5p and miR‐942‐5p to suppress colorectal cancer progression by regulating the PTEN/AKT signalling pathway

(2021) Zhipeng Jiang et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

A Proton-Coupled Transport System for β-Hydroxy-β-Methylbutyrate (HMB) in Blood–Brain Barrier Endothelial Cell Line hCMEC/D3

(2021) Kei Higuchi et al.   Nutrients

Fe-doped chrysotile nanotubes containing siRNAs to silence SPAG5 to treat bladder cancer

(2021) Jianye Liu et al.   JOURNAL OF NANOBIOTECHNOLOGY

Neutrophil Delivered Hollow Titania Covered Persistent Luminescent Nanosensitizer for Ultrosound Augmented Chemo/Immuno Glioblastoma Therapy

(2021) Yujie Li et al.   Advanced Science

Glucose oxidase and L-arginine functionalized black phosphorus nanosheets for multimodal targeted therapy of glioblastoma

(2021) Xin Huang et al.   CHEMICAL ENGINEERING JOURNAL

Lactic acid in tumor invasion

(2021) Dun Niu et al.   CLINICA CHIMICA ACTA

From phosphorus to phosphorene: Applications in disease theranostics

(2021) Yao Zhu et al.   COORDINATION CHEMISTRY REVIEWS

Neodymium (3+)‐Coordinated Black Phosphorus Quantum Dots with Retrievable NIR/X‐Ray Optoelectronic Switching Effect for Anti‐Glioblastoma

(2021) Zhi Li et al.   Small

Modeling ischemic stroke in a triculture neurovascular unit on-a-chip

(2021) Nienke R. Wevers et al.   Fluids and Barriers of the CNS

Lipoprotein-biomimetic nanostructure enables tumor-targeted penetration delivery for enhanced photo-gene therapy towards glioma

(2021) Ruoning Wang et al.   Bioactive Materials

A Novel Pt–TiO 2 Heterostructure with Oxygen‐Deficient Layer as Bilaterally Enhanced Sonosensitizer for Synergistic Chemo‐Sonodynamic Cancer Therapy

(2020) Shuang Liang et al.   ADVANCED FUNCTIONAL MATERIALS

Autocatalytic Delivery of Brain Tumor–Targeting, Size‐Shrinkable Nanoparticles for Treatment of Breast Cancer Brain Metastases

(2020) Shenqi Zhang et al.   ADVANCED FUNCTIONAL MATERIALS

Sequential Targeting in Crosslinking Nanotheranostics for Tackling the Multibarriers of Brain Tumors

(2020) Hao Wu et al.   ADVANCED MATERIALS

Multiplexed NIR‐II Probes for Lymph Node‐Invaded Cancer Detection and Imaging‐Guided Surgery

(2020) Rui Tian et al.   ADVANCED MATERIALS

A Sox2/miR-486-5p axis regulates survival of GBM cells by inhibiting tumor suppressor networks

(2020) Hernando Lopez-Bertoni et al.   CANCER RESEARCH

Tumor treating fields plus temozolomide for newly diagnosed glioblastoma: a sub-group analysis of Korean patients in the EF-14 phase 3 trial

(2020) Chae-Yong Kim et al.   JOURNAL OF NEURO-ONCOLOGY

Charge Conversional Biomimetic Nanocomplexes as a Multifunctional Platform for Boosting Orthotopic Glioblastoma RNAi Therapy

(2020) Yanjie Liu et al.   NANO LETTERS

Intelligent Nanocomposites with Intrinsic Blood–Brain‐Barrier Crossing Ability Designed for Highly Specific MR Imaging and Sonodynamic Therapy of Glioblastoma

(2020) Kaicheng Liang et al.   Small

Response of pH-Sensitive Doxorubicin Nanoparticles on Complex Tumor Microenvironments by Tailoring Multiple Physicochemical Properties

(2020) Huajian Chen et al.   ACS Applied Materials & Interfaces

In Situ Formation of Nanotheranostics to Overcome the Blood–Brain–Barrier and Enhance Treatment of Orthotopic Glioma

(2020) Haiyan Gao et al.   ACS Applied Materials & Interfaces

Single siRNA Nanocapsules for Effective siRNA Brain Delivery and Glioblastoma Treatment

(2020) Yan Zou et al.   ADVANCED MATERIALS

L-Type amino acid transporter 1 as a target for drug delivery

(2020) Elena Puris et al.   PHARMACEUTICAL RESEARCH

Controlled Synthesis of Ag 2 Te@Ag 2 S Core–Shell Quantum Dots with Enhanced and Tunable Fluorescence in the Second Near‐Infrared Window

(2020) Yejun Zhang et al.   Small

Near Infrared Fluorescent Nanoplatform for Targeted Intraoperative Resection and Chemotherapeutic Treatment of Glioblastoma

(2020) Derek Reichel et al.   ACS Nano

Biomimetic Nanocomposites Cloaked with Bioorthogonally Labeled Glioblastoma Cell Membrane for Targeted Multimodal Imaging of Brain Tumors

(2020) Yukun Duan et al.   ADVANCED FUNCTIONAL MATERIALS

Comprehensive Genomic Analysis in NRG Oncology/RTOG 9802: A Phase III Trial of Radiation Versus Radiation Plus Procarbazine, Lomustine (CCNU), and Vincristine in High-Risk Low-Grade Glioma

(2020) Erica H. Bell et al.   JOURNAL OF CLINICAL ONCOLOGY

Acid‐Induced In Vivo Assembly of Gold Nanoparticles for Enhanced Photoacoustic Imaging‐Guided Photothermal Therapy of Tumors

(2020) Ruili Zhang et al.   Advanced Healthcare Materials

Blood-Brain Barrier, Blood-Brain Tumor Barrier, and Fluorescence-Guided Neurosurgical Oncology: Delivering Optical Labels to Brain Tumors

(2020) Evgenii Belykh et al.   Frontiers in Oncology

Natural-Killer-Cell-Inspired Nanorobots with Aggregation-Induced Emission Characteristics for Near-Infrared-II Fluorescence-Guided Glioma Theranostics

(2020) Guanjun Deng et al.   ACS Nano

COVID-19 vaccine BNT162b1 elicits human antibody and TH1 T cell responses

(2020) Ugur Sahin et al.   NATURE

Tiny 2D silicon quantum sheets: a brain photonic nanoagent for orthotopic glioma theranostics

(2020) Zhaohua Miao et al.   Science Bulletin

Oncogenic and Tumor-Suppressive Functions of NOTCH Signaling in Glioma

(2020) Elena Parmigiani et al.   Cells

A Systematic Review of Molecular Imaging Agents Targeting Bradykinin B1 and B2 Receptors

(2020) Joseph Lau et al.   Pharmaceuticals

Environmentally Self-Adaptative Nanocarriers Suppress Glioma Proliferation and Stemness via Codelivery of shCD163 and Doxorubicin

(2020) Jie Liu et al.   ACS Applied Materials & Interfaces

Citric acid coated ultrasmall superparamagnetic iron oxide nanoparticles conjugated with lactoferrin for targeted negative MR imaging of glioma

(2020) Ruolei Xiao et al.   JOURNAL OF BIOMATERIALS APPLICATIONS

Multifunctionalized Gold Sub‐Nanometer Particles for Sensitizing Radiotherapy against Glioblastoma

(2020) Cheng‐Yuan Dong et al.   Small

T Cell‐Mediated Transport of Polymer Nanoparticles across the Blood–Brain Barrier

(2020) Maxime Ayer et al.   Advanced Healthcare Materials

MIR93 (microRNA -93) Regulates Tumorigenicity and Therapy Response of Glioblastoma by Targeting Autophagy

(2019) Tianzhi Huang et al.   Autophagy

Hyaluronic acid tethered pH-responsive alloy-drug nanoconjugates for multimodal therapy of glioblastoma: An intranasal route approach

(2019) Abhijeet Pandey et al.   Materials Science & Engineering C-Materials for Biological Applications

Enhanced Radiosensitization by Gold Nanoparticles with Acid-Triggered Aggregation in Cancer Radiotherapy

(2019) Yumin Zhang et al.   Advanced Science

Alternating Electric Fields (TTFields) Activate Cav1.2 Channels in Human Glioblastoma Cells

(2019) Eric Neuhaus et al.   Cancers

Temozolomide Induced Hypermutation in Glioma: Evolutionary Mechanisms and Therapeutic Opportunities

(2019) Paul Daniel et al.   Frontiers in Oncology

Treatment of Glioblastoma (GBM) with the Addition of Tumor-Treating Fields (TTF): A Review

(2019) Denise Fabian et al.   Cancers

Exosomal transfer of miR-1238 contributes to temozolomide-resistance in glioblastoma

(2019) Jianxing Yin et al.   EBioMedicine

Safety and Feasibility of Repeated and Transient Blood-Brain Barrier Disruption by Pulsed Ultrasound in Patients with Recurrent Glioblastoma

(2019) Ahmed Idbaih et al.   CLINICAL CANCER RESEARCH

Systemic Delivery of Monoclonal Antibodies to the Central Nervous System for Brain Tumor Therapy

(2019) Lei Han et al.   ADVANCED MATERIALS

Photoacoustic Therapy for Precise Eradication of Glioblastoma with a Tumor Site Blood-Brain Barrier Permeability Upregulating Nanoparticle

(2019) Liming Liu et al.   ADVANCED FUNCTIONAL MATERIALS

Radiation-Induced Targeted Nanoparticle-Based Gene Delivery for Brain Tumor Therapy

(2019) Gulsah Erel-Akbaba et al.   ACS Nano

Enhancing Boron Uptake in Brain Glioma by a Boron-Polymer/Microbubble Complex with Focused Ultrasound

(2019) Ching-Hsiang Fan et al.   ACS Applied Materials & Interfaces

Brain and bone cancer targeting by a ferrofluid composed of superparamagnetic iron-oxide/silica/carbon nanoparticles (earthicles)

(2019) Victoria M. Wu et al.   Acta Biomaterialia

Nanoparticles Surmounting Blood–Brain Tumor Barrier Through Both Transcellular and Paracellular Pathways to Target Brain Metastases

(2019) Tongtong Miao et al.   ADVANCED FUNCTIONAL MATERIALS

Delta-24-RGD combined with radiotherapy exerts a potent antitumor effect in diffuse intrinsic pontine glioma and pediatric high grade glioma models

(2019) Naiara Martinez-Velez et al.   Acta Neuropathologica Communications

ROS‐Responsive Polymeric siRNA Nanomedicine Stabilized by Triple Interactions for the Robust Glioblastoma Combinational RNAi Therapy

(2019) Meng Zheng et al.   ADVANCED MATERIALS

Recent Advances in Small Copper Sulfide Nanoparticles for Molecular Imaging and Tumor Therapy

(2019) Yang Liu et al.   MOLECULAR PHARMACEUTICS

The Role of Adaptor Proteins in the Biology of Natural Killer T (NKT) Cells

(2019) Evelyn Gerth et al.   Frontiers in Immunology

Scaffolds biomimicking macrophages for a glioblastoma NIR-Ib imaging guided photothermal therapeutic strategy by crossing Blood-Brain Barrier

(2019) Jiazheng Lai et al.   BIOMATERIALS

Molecular Targeting Nanoprobes with Non-Overlap Emission in the Second Near-Infrared Window for in Vivo Two-Color Colocalization of Immune Cells

(2019) Guang-Tao Yu et al.   ACS Nano

Fast‐Acting Black‐Phosphorus‐Assisted Depression Therapy with Low Toxicity

(2019) Liguo Jin et al.   ADVANCED MATERIALS

Boosting often overlooked long wavelength emissions of rare-earth nanoparticles for NIR-II fluorescence imaging of orthotopic glioblastoma

(2019) Zheng Liu et al.   BIOMATERIALS

Vitexin, an inhibitor of hypoxia-inducible factor-1α, enhances the radiotherapy sensitization of hyperbaric oxygen on glioma

(2019) T. Xie et al.   Clinical & Translational Oncology

DNX-2401: an investigational drug for the treatment of recurrent glioblastoma

(2019) Brandon Philbrick et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Therapeutic Prospects of mRNA-Based Gene Therapy for Glioblastoma

(2019) Xiangjun Tang et al.   Frontiers in Oncology

An iRGD-conjugated prodrug micelle with blood-brain-barrier penetrability for anti-glioma therapy

(2019) Lu Lu et al.   BIOMATERIALS

Large-scale generation of functional mRNA-encapsulating exosomes via cellular nanoporation

(2019) Zhaogang Yang et al.   Nature Biomedical Engineering

Enhanced Photogeneration of Reactive Oxygen Species and Targeted Photothermal Therapy of C6 Glioma Brain Cancer Cells by Folate-Conjugated Gold–Photoactive Polymer Nanoparticles

(2018) Jaber Keyvan Rad et al.   ACS Applied Materials & Interfaces

Highly Crystalline Multicolor Carbon Nanodots for Dual-Modal Imaging-Guided Photothermal Therapy of Glioma

(2018) Min Qian et al.   ACS Applied Materials & Interfaces

Oxygen-Deficient Black Titania for Synergistic/Enhanced Sonodynamic and Photoinduced Cancer Therapy at Near Infrared-II Biowindow

(2018) Xiaoxia Han et al.   ACS Nano

Self-Assembled pH-Sensitive Fluoromagnetic Nanotubes as Archetype System for Multimodal Imaging of Brain Cancer

(2018) Chiara Villa et al.   ADVANCED FUNCTIONAL MATERIALS

Synergistic Sonodynamic/Chemotherapeutic Suppression of Hepatocellular Carcinoma by Targeted Biodegradable Mesoporous Nanosonosensitizers

(2018) Zhenli Li et al.   ADVANCED FUNCTIONAL MATERIALS

iRGD Modified Chemo-immunotherapeutic Nanoparticles for Enhanced Immunotherapy against Glioblastoma

(2018) Jing Kuang et al.   ADVANCED FUNCTIONAL MATERIALS

Tumor Microenvironment-Responsive Mesoporous MnO2 -Coated Upconversion Nanoplatform for Self-Enhanced Tumor Theranostics

(2018) Jiating Xu et al.   ADVANCED FUNCTIONAL MATERIALS

Traceable Nanoparticles with Dual Targeting and ROS Response for RNAi-Based Immunochemotherapy of Intracranial Glioblastoma Treatment

(2018) Chenmeng Qiao et al.   ADVANCED MATERIALS

Protein Toxin Chaperoned by LRP-1-Targeted Virus-Mimicking Vesicles Induces High-Efficiency Glioblastoma Therapy In Vivo

(2018) Yu Jiang et al.   ADVANCED MATERIALS

Bright Aggregation-Induced-Emission Dots for Targeted Synergetic NIR-II Fluorescence and NIR-I Photoacoustic Imaging of Orthotopic Brain Tumors

(2018) Zonghai Sheng et al.   ADVANCED MATERIALS

A Novel Top-Down Synthesis of Ultrathin 2D Boron Nanosheets for Multimodal Imaging-Guided Cancer Therapy

(2018) Xiaoyuan Ji et al.   ADVANCED MATERIALS

NRP-1 targeted and cargo-loaded exosomes facilitate simultaneous imaging and therapy of glioma in vitro and in vivo

(2018) Gang Jia et al.   BIOMATERIALS

Molecular, Pathological, Radiological, and Immune Profiling of Non-brainstem Pediatric High-Grade Glioma from the HERBY Phase II Randomized Trial

(2018) Alan Mackay et al.   CANCER CELL

Monitoring the Opening and Recovery of the Blood–Brain Barrier with Noninvasive Molecular Imaging by Biodegradable Ultrasmall Cu2–xSe Nanoparticles

(2018) Hao Zhang et al.   NANO LETTERS

Oncolytic virotherapy in glioblastoma patients induces a tumor macrophage phenotypic shift leading to an altered glioblastoma microenvironment

(2018) Wouter B L van den Bossche et al.   NEURO-ONCOLOGY

CAR T-cell therapy for glioblastoma: recent clinical advances and future challenges

(2018) Stephen J Bagley et al.   NEURO-ONCOLOGY

Development of third generation anti-EGFRvIII chimeric T cells and EGFRvIII-expressing artificial antigen presenting cells for adoptive cell therapy for glioma

(2018) Ayguen Sahin et al.   PLoS One

Bright quantum dots emitting at ∼1,600 nm in the NIR-IIb window for deep tissue fluorescence imaging

(2018) Mingxi Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dendritic cell activation enhances anti-PD-1 mediated immunotherapy against glioblastoma

(2018) Tomas Garzon-Muvdi et al.   Oncotarget

Highly Sensitive MoS2–Indocyanine Green Hybrid for Photoacoustic Imaging of Orthotopic Brain Glioma at Deep Site

(2018) Chengbo Liu et al.   Nano-Micro Letters

Highly Sensitive MoS2–Indocyanine Green Hybrid for Photoacoustic Imaging of Orthotopic Brain Glioma at Deep Site

(2018) Chengbo Liu et al.   Nano-Micro Letters

Focused Ultrasound-Augmented Delivery of Biodegradable Multifunctional Nanoplatforms for Imaging-Guided Brain Tumor Treatment

(2018) Meiying Wu et al.   Advanced Science

Novel Approaches to Exploiting Invariant NKT Cells in Cancer Immunotherapy

(2018) Benjamin J. Wolf et al.   Frontiers in Immunology

Association of MGMT Promoter Methylation Status With Survival Outcomes in Patients With High-Risk Glioma Treated With Radiotherapy and Temozolomide

(2018) Erica H. Bell et al.   JAMA Oncology

Through Scalp and Skull NIR-II Photothermal Therapy of Deep Orthotopic Brain Tumors with Precise Photoacoustic Imaging Guidance

(2018) Bing Guo et al.   ADVANCED MATERIALS

Liposomes and polymersomes: a comparative review towards cell mimicking

(2018) Emeline Rideau et al.   CHEMICAL SOCIETY REVIEWS

Evaluation of Toxicity and Neural Uptake In Vitro and In Vivo of Superparamagnetic Iron Oxide Nanoparticles

(2018) Muhammad Khalid et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Gamma knife radiosurgery for recurrent gliomas

(2018) Zjiwar H. A. Sadik et al.   JOURNAL OF NEURO-ONCOLOGY

Combination Glioma Therapy Mediated by a Dual-Targeted Delivery System Constructed Using OMCN-PEG-Pep22/DOX

(2018) Wenbo Qian et al.   Small

Neutrophil-Based Delivery Systems for Nanotherapeutics

(2018) Yu Han et al.   Small

Transport and interactions of nanoparticles in the kidneys

(2018) Bujie Du et al.   Nature Reviews Materials

Dual-Modified Novel Biomimetic Nanocarriers Improve Targeting and Therapeutic Efficacy in Glioma

(2018) Shiyao Fu et al.   ACS Applied Materials & Interfaces

Magnetic Targeting, Tumor Microenvironment-Responsive Intelligent Nanocatalysts for Enhanced Tumor Ablation

(2018) Lili Feng et al.   ACS Nano

Phototheranostics: Active Targeting of Orthotopic Glioma Using Biomimetic Proteolipid Nanoparticles

(2018) Yali Jia et al.   ACS Nano

Transferrin/aptamer conjugated mesoporous ruthenium nanosystem for redox-controlled and targeted chemo-photodynamic therapy of glioma

(2018) Xufeng Zhu et al.   Acta Biomaterialia

Effective and Targeted Human Orthotopic Glioblastoma Xenograft Therapy via a Multifunctional Biomimetic Nanomedicine

(2018) Yan Zou et al.   ADVANCED MATERIALS

Solid lipid nanoparticles and nanostructured lipid carriers: A review emphasizing on particle structure and drug release

(2018) Aldemar Gordillo-Galeano et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Overcoming multiple drug resistance in cancer using polymeric micelles

(2018) Siddharth S. Kesharwani et al.   Expert Opinion on Drug Delivery

Functional Biological Activity of Sorafenib as a Tumor-Treating Field Sensitizer for Glioblastoma Therapy

(2018) Yunhui Jo et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Doxorubicin and indocyanine green loaded superparamagnetic iron oxide nanoparticles with PEGylated phospholipid coating for magnetic resonance with fluorescence imaging and chemotherapy of glioma

(2018) Chen Shen et al.   International Journal of Nanomedicine

The EGFR variant III mutant as a target for immunotherapy of glioblastoma multiforme

(2017) Dimitry A. Chistiakov et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

TGF-β-Induced Endothelial-Mesenchymal Transition in Fibrotic Diseases

(2017) Evangelia Pardali et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Preliminary results of immune modulating antibody MDV9300 (pidilizumab) treatment in children with diffuse intrinsic pontine glioma

(2017) Iris Fried et al.   JOURNAL OF NEURO-ONCOLOGY

Neutrophil-mediated anticancer drug delivery for suppression of postoperative malignant glioma recurrence

(2017) Jingwei Xue et al.   Nature Nanotechnology

Manganese Dioxide Coated WS2 @Fe3 O4 /sSiO2 Nanocomposites for pH-Responsive MR Imaging and Oxygen-Elevated Synergetic Therapy

(2017) Guangbao Yang et al.   Small

Biocompatible conjugated polymer nanoparticles for highly efficient photoacoustic imaging of orthotopic brain tumors in the second near-infrared window

(2017) Bing Guo et al.   Materials Horizons

Ultrasound-triggered local anaesthesia

(2017) Alina Y. Rwei et al.   Nature Biomedical Engineering

High-Density Lipoproteins: Nature’s Multifunctional Nanoparticles

(2016) Rui Kuai et al.   ACS Nano

Increased Gold Nanoparticle Retention in Brain Tumors by in Situ Enzyme-Induced Aggregation

(2016) Shaobo Ruan et al.   ACS Nano

The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary

(2016) David N. Louis et al.   ACTA NEUROPATHOLOGICA

Single-Layer MoS2Nanosheets with Amplified Photoacoustic Effect for Highly Sensitive Photoacoustic Imaging of Orthotopic Brain Tumors

(2016) Jingqin Chen et al.   ADVANCED FUNCTIONAL MATERIALS

Large amino acid transporter 1 mediated glutamate modified docetaxel-loaded liposomes for glioma targeting

(2016) Lin Li et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

An Overview of Alternating Electric Fields Therapy (NovoTTF Therapy) for the Treatment of Malignant Glioma

(2016) Kenneth D. Swanson et al.   Current Neurology and Neuroscience Reports

Downregulation of HIF-1a sensitizes U251 glioma cells to the temozolomide (TMZ) treatment

(2016) Jun-Hai Tang et al.   EXPERIMENTAL CELL RESEARCH

Synthetic high-density lipoproteins for delivery of 10-hydroxycamptothecin

(2016) Yue Yuan et al.   International Journal of Nanomedicine

Extracellular vesicle isolation and characterization: toward clinical application

(2016) Rong Xu et al.   JOURNAL OF CLINICAL INVESTIGATION

Tandem CAR T cells targeting HER2 and IL13Rα2 mitigate tumor antigen escape

(2016) Meenakshi Hegde et al.   JOURNAL OF CLINICAL INVESTIGATION

Non-invasive, neuron-specific gene therapy by focused ultrasound-induced blood-brain barrier opening in Parkinson's disease mouse model

(2016) Chung-Yin Lin et al.   JOURNAL OF CONTROLLED RELEASE

Nanoparticle-mediated brain drug delivery: Overcoming blood–brain barrier to treat neurodegenerative diseases

(2016) Cláudia Saraiva et al.   JOURNAL OF CONTROLLED RELEASE

Exosomal miR-221 targets DNM3 to induce tumor progression and temozolomide resistance in glioma

(2016) Jian-Kai Yang et al.   JOURNAL OF NEURO-ONCOLOGY

Clinically Approved Nanoparticle Imaging Agents

(2016) A. S. Thakor et al.   JOURNAL OF NUCLEAR MEDICINE

Long-Circulating Au-TiO2 Nanocomposite as a Sonosensitizer for ROS-Mediated Eradication of Cancer

(2016) V. G. Deepagan et al.   NANO LETTERS

The role of microglia and macrophages in glioma maintenance and progression

(2016) Dolores Hambardzumyan et al.   NATURE NEUROSCIENCE

Regression of Glioblastoma after Chimeric Antigen Receptor T-Cell Therapy

(2016) Christine E. Brown et al.   NEW ENGLAND JOURNAL OF MEDICINE

Epithelial-mesenchymal transition in glioblastoma progression

(2016) YASUO IWADATE   Oncology Letters

Biodegradable black phosphorus-based nanospheres for in vivo photothermal cancer therapy

(2016) Jundong Shao et al.   Nature Communications

Cell line with endogenous EGFRvIII expression is a suitable model for research and drug development purposes

(2016) Wojciech J. Stec et al.   Oncotarget

Reactive Oxygen Species-Manipulated Drug Release from a Smart Envelope-Type Mesoporous Titanium Nanovehicle for Tumor Sonodynamic-Chemotherapy

(2015) Jinjin Shi et al.   ACS Applied Materials & Interfaces

Tumor Microenvironment Activated Photothermal Strategy for Precisely Controlled Ablation of Solid Tumors upon NIR Irradiation

(2015) Enguo Ju et al.   ADVANCED FUNCTIONAL MATERIALS

Endothelial Jagged1 Antagonizes Dll4 Regulation of Endothelial Branching and Promotes Vascular Maturation Downstream of Dll4/Notch1

(2015) A.-R. Pedrosa et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Brain tumor-targeted delivery and therapy by focused ultrasound introduced doxorubicin-loaded cationic liposomes

(2015) Qian Lin et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Lanthanide Nanoparticles: From Design toward Bioimaging and Therapy

(2015) Hao Dong et al.   CHEMICAL REVIEWS

Brain–blood ratio: implications in brain drug delivery

(2015) Abhijeet D Kulkarni et al.   Expert Opinion on Drug Delivery

Chitosan as a suitable nanocarrier material for anti-Alzheimer drug delivery

(2015) Jayrajsinh Sarvaiya et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Economic Evaluation of Bevacizumab for the First-Line Treatment of Newly Diagnosed Glioblastoma Multiforme

(2015) Bruno Kovic et al.   JOURNAL OF CLINICAL ONCOLOGY

Oxygen carrying microbubbles for enhanced sonodynamic therapy of hypoxic tumours

(2015) Conor McEwan et al.   JOURNAL OF CONTROLLED RELEASE

Nanoparticle-loaded macrophage-mediated photothermal therapy: potential for glioma treatment

(2015) Steen J. Madsen et al.   LASERS IN MEDICAL SCIENCE

Compact chelator-free Ni-integrated CuS nanoparticles with tunable near-infrared absorption and enhanced relaxivity for in vivo dual-modal photoacoustic/MR imaging

(2015) Duyang Gao et al.   Nanoscale

Insulator dysfunction and oncogene activation in IDH mutant gliomas

(2015) William A. Flavahan et al.   NATURE

Silencing of HIF-1α enhances the radiation sensitivity of human glioma growth in vitro and in vivo

(2015) Zhonghua Luo et al.   NEUROPHARMACOLOGY

Molecular features assisting in diagnosis, surgery, and treatment decision making in low-grade gliomas

(2015) Ricky Chen et al.   Neurosurgical Focus

Nanosystems: the use of nanoalloys, metallic, bimetallic, and magnetic nanoparticles in biomedical applications

(2015) Karrina McNamara et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Exosomes and their roles in immune regulation and cancer

(2015) David W. Greening et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Mitotic Spindle Disruption by Alternating Electric Fields Leads to Improper Chromosome Segregation and Mitotic Catastrophe in Cancer Cells

(2015) Moshe Giladi et al.   Scientific Reports

Histone H3 Phosphorylation in GBM: a New Rational to Guide the Use of Kinase Inhibitors in anti-GBM Therapy

(2015) Romain Pacaud et al.   Theranostics

5-ALA fluorescence-assisted surgery in pediatric brain tumors: Report of three cases and review of the literature

(2014) Giuseppe M. V. Barbagallo et al.   BRITISH JOURNAL OF NEUROSURGERY

Dendritic Cell-Based Vaccine for the Treatment of Malignant Glioma: A Systematic Review

(2014) Xuan Wang et al.   CANCER INVESTIGATION

Surface modified PLGA nanoparticles for brain targeting of Bacoside-A

(2014) S. Jose et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Activation of Glioma Cells Generates Immune Tolerant NKT Cells

(2014) Bo Tang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The role of radiotherapy in the management of progressive glioblastoma

(2014) Samuel Ryu et al.   JOURNAL OF NEURO-ONCOLOGY

Through-skull fluorescence imaging of the brain in a new near-infrared window

(2014) Guosong Hong et al.   Nature Photonics

MGMT testing—the challenges for biomarker-based glioma treatment

(2014) Wolfgang Wick et al.   Nature Reviews Neurology

Epidermal growth factor receptor and variant III targeted immunotherapy

(2014) K. L. Congdon et al.   NEURO-ONCOLOGY

Differential regulation of TGF-β–induced, ALK-5–mediated VEGF release by SMAD2/3 versus SMAD1/5/8 signaling in glioblastoma

(2014) Katharina Seystahl et al.   NEURO-ONCOLOGY

A Randomized Trial of Bevacizumab for Newly Diagnosed Glioblastoma

(2014) Mark R. Gilbert et al.   NEW ENGLAND JOURNAL OF MEDICINE

Fluorescence-guided resection of high-grade gliomas: A systematic review and meta-analysis

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EGFR Phosphorylates Tumor-Derived EGFRvIII Driving STAT3/5 and Progression in Glioblastoma

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