Molecular mechanisms in atopic eczema: insights gained from genetic studies
Published 2016 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Molecular mechanisms in atopic eczema: insights gained from genetic studies
Authors
Keywords
-
Journal
JOURNAL OF PATHOLOGY
Volume 241, Issue 2, Pages 140-145
Publisher
Wiley
Online
2016-09-23
DOI
10.1002/path.4810
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- An IL-17–dominant immune profile is shared across the major orphan forms of ichthyosis
- (2017) Amy S. Paller et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Association between atopic dermatitis and attention deficit hyperactivity disorder in U.S. children and adults
- (2016) M.A. Strom et al. BRITISH JOURNAL OF DERMATOLOGY
- Atopic eczema
- (2016) S. J. Brown CLINICAL MEDICINE
- Skin barrier impairment at birth predicts food allergy at 2 years of age
- (2016) Maeve M. Kelleher et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Atopic dermatitis is associated with an increased risk for rheumatoid arthritis and inflammatory bowel disease, and a decreased risk for type 1 diabetes
- (2016) Jochen Schmitt et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Efficacy and safety of crisaborole ointment, a novel, nonsteroidal phosphodiesterase 4 (PDE4) inhibitor for the topical treatment of atopic dermatitis (AD) in children and adults
- (2016) Amy S. Paller et al. JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
- Dupilumab: a milestone in the treatment of atopic dermatitis
- (2016) Athanasios Tsianakas et al. LANCET
- Efficacy and safety of dupilumab in adults with moderate-to-severe atopic dermatitis inadequately controlled by topical treatments: a randomised, placebo-controlled, dose-ranging phase 2b trial
- (2016) Diamant Thaçi et al. LANCET
- Genome-wide Comparative Analysis of Atopic Dermatitis and Psoriasis Gives Insight into Opposing Genetic Mechanisms
- (2015) Hansjörg Baurecht et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Desmosome regulation and signaling in disease
- (2015) Joshua A. Broussard et al. CELL AND TISSUE RESEARCH
- Association of HLA-DRB1 genetic variants with the persistence of atopic dermatitis
- (2015) David J. Margolis et al. HUMAN IMMUNOLOGY
- Whole-exome sequencing of Ethiopian patients with ichthyosis vulgaris and atopic dermatitis
- (2015) Fulya Taylan et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Severe dermatitis, multiple allergies, and metabolic wasting syndrome caused by a novel mutation in the N-terminal plakin domain of desmoplakin
- (2015) Maeve A. McAleer et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Skin barrier dysfunction measured by transepidermal water loss at 2 days and 2 months predates and predicts atopic dermatitis at 1 year
- (2015) Maeve Kelleher et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- The translational revolution and use of biologics in patients with inflammatory skin diseases
- (2015) Shinji Noda et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- RNA sequencing atopic dermatitis transcriptome profiling provides insights into novel disease mechanisms with potential therapeutic implications
- (2015) Mayte Suárez-Fariñas et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Identification of novel immune and barrier genes in atopic dermatitis by means of laser capture microdissection
- (2015) Hitokazu Esaki et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Lin He: “Junk” DNA isn’t
- (2015) Caitlin Sedwick JOURNAL OF CELL BIOLOGY
- Association of atopic dermatitis with being overweight and obese: A systematic review and metaanalysis
- (2015) April Zhang et al. JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
- Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis
- (2015) Lavinia Paternoster et al. NATURE GENETICS
- Using human genetics to make new medicines
- (2015) Jeffrey C. Barrett et al. NATURE REVIEWS GENETICS
- Central Obesity and High Blood Pressure in Pediatric Patients With Atopic Dermatitis
- (2015) Jonathan I. Silverberg et al. JAMA Dermatology
- Multiple Transcriptome Data Analysis Reveals Biologically Relevant Atopic Dermatitis Signature Genes and Pathways
- (2015) Debajyoti Ghosh et al. PLoS One
- Emollient enhancement of the skin barrier from birth offers effective atopic dermatitis prevention
- (2014) Eric L. Simpson et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Application of moisturizer to neonates prevents development of atopic dermatitis
- (2014) Kenta Horimukai et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Filaggrin-stratified transcriptomic analysis of pediatric skin identifies mechanistic pathways in patients with atopic dermatitis
- (2014) Christian Cole et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Exome Sequencing of Filaggrin and Related Genes in African-American Children with Atopic Dermatitis
- (2014) David J. Margolis et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Allelic expression mapping across cellular lineages to establish impact of non-coding SNPs
- (2014) V. Adoue et al. Molecular Systems Biology
- Dupilumab Treatment in Adults with Moderate-to-Severe Atopic Dermatitis
- (2014) Lisa A. Beck et al. NEW ENGLAND JOURNAL OF MEDICINE
- Nonallergic comorbidities of atopic eczema: an overview of systematic reviews
- (2013) S. Deckert et al. ALLERGY
- Increased efficacy of omalizumab in atopic dermatitis patients with wild-type filaggrin status and higher serum levels of phosphatidylcholines
- (2013) M. Hotze et al. ALLERGY
- Desmoglein 1 deficiency results in severe dermatitis, multiple allergies and metabolic wasting
- (2013) Liat Samuelov et al. NATURE GENETICS
- Does “autoreactivity” play a role in atopic dermatitis?
- (2012) Ting Seng Tang et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Atopic dermatitis: a disease of altered skin barrier and immune dysregulation
- (2011) Mark Boguniewicz et al. IMMUNOLOGICAL REVIEWS
- TNF-α Downregulates Filaggrin and Loricrin through c-Jun N-terminal Kinase: Role for TNF-α Antagonists to Improve Skin Barrier
- (2011) Byung Eui Kim et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Intragenic Copy Number Variation within Filaggrin Contributes to the Risk of Atopic Dermatitis with a Dose-Dependent Effect
- (2011) Sara J. Brown et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- One Remarkable Molecule: Filaggrin
- (2011) Sara J. Brown et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Mutual Antagonism of T Cells Causing Psoriasis and Atopic Eczema
- (2011) Stefanie Eyerich et al. NEW ENGLAND JOURNAL OF MEDICINE
- Filaggrin Mutations Associated with Skin and Allergic Diseases
- (2011) Alan D. Irvine et al. NEW ENGLAND JOURNAL OF MEDICINE
- Barrier Dysfunction Caused by Environmental Proteases in the Pathogenesis of Allergic Diseases
- (2011) Toshiro Takai et al. ALLERGOLOGY INTERNATIONAL
- Psychiatric comorbidity in adult eczema
- (2009) J. Schmitt et al. BRITISH JOURNAL OF DERMATOLOGY
- Filaggrin haploinsufficiency is highly penetrant and is associated with increased severity of eczema: further delineation of the skin phenotype in a prospective epidemiological study of 792 school children
- (2009) S.J. Brown et al. BRITISH JOURNAL OF DERMATOLOGY
- Meta-analysis of filaggrin polymorphisms in eczema and asthma: Robust risk factors in atopic disease
- (2009) Elke Rodríguez et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Filaggrin mutations that confer risk of atopic dermatitis confer greater risk for eczema herpeticum
- (2009) Pei-Song Gao et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Global variations in prevalence of eczema symptoms in children from ISAAC Phase Three
- (2009) Joseph A. Odhiambo et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Filaggrin in the frontline: role in skin barrier function and disease
- (2009) A. Sandilands et al. JOURNAL OF CELL SCIENCE
- Eczema Genetics: Current State of Knowledge and Future Goals
- (2009) Sara J. Brown et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- A common variant on chromosome 11q13 is associated with atopic dermatitis
- (2009) Jorge Esparza-Gordillo et al. NATURE GENETICS
- Analysis of the individual and aggregate genetic contributions of previously identified serine peptidase inhibitor Kazal type 5 (SPINK5), kallikrein-related peptidase 7 (KLK7), and filaggrin (FLG) polymorphisms to eczema risk
- (2008) Stephan Weidinger et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- The burden of disease associated with filaggrin mutations: A population-based, longitudinal birth cohort study
- (2008) John Henderson et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Filaggrin null mutations and childhood atopic eczema: A population-based case-control study
- (2008) Sara J. Brown et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Atopic Dermatitis
- (2008) Thomas Bieber NEW ENGLAND JOURNAL OF MEDICINE
- Prevalent and Low-Frequency Null Mutations in the Filaggrin Gene Are Associated with Early-Onset and Persistent Atopic Eczema
- (2007) Sara J. Brown et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started