Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis

Genome-wide Comparative Analysis of Atopic Dermatitis and Psoriasis Gives Insight into Opposing Genetic Mechanisms

(2015) Hansjörg Baurecht et al.   AMERICAN JOURNAL OF HUMAN GENETICS

A mouse model of HIES reveals pro- and anti-inflammatory functions of STAT3

(2014) S. M. Steward-Tharp et al.   BLOOD

Filaggrin-stratified transcriptomic analysis of pediatric skin identifies mechanistic pathways in patients with atopic dermatitis

(2014) Christian Cole et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype

(2014) Manuel A.R. Ferreira et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Dupilumab Treatment in Adults with Moderate-to-Severe Atopic Dermatitis

(2014) Lisa A. Beck et al.   NEW ENGLAND JOURNAL OF MEDICINE

Bayesian Test for Colocalisation between Pairs of Genetic Association Studies Using Summary Statistics

(2014) Claudia Giambartolomei et al.   PLoS Genetics

A Nondegenerate Code of Deleterious Variants in Mendelian Loci Contributes to Complex Disease Risk

(2013) David R. Blair et al.   CELL

Comparing methods for performing trans-ethnic meta-analysis of genome-wide association studies

(2013) Xu Wang et al.   HUMAN MOLECULAR GENETICS

A genome-wide association study of atopic dermatitis identifies loci with overlapping effects on asthma and psoriasis

(2013) Stephan Weidinger et al.   HUMAN MOLECULAR GENETICS

A functional IL-6 receptor (IL6R) variant is a risk factor for persistent atopic dermatitis

(2013) Jorge Esparza-Gordillo et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Genetics of rheumatoid arthritis contributes to biology and drug discovery

(2013) Yukinori Okada et al.   NATURE

High-density genotyping study identifies four new susceptibility loci for atopic dermatitis

(2013) David Ellinghaus et al.   NATURE GENETICS

Identification of multiple risk variants for ankylosing spondylitis through high-density genotyping of immune-related loci

(2013) Adrian Cortes et al.   NATURE GENETICS

Evaluating empirical bounds on complex disease genetic architecture

(2013) Vineeta Agarwala et al.   NATURE GENETICS

A genome-wide association meta-analysis of self-reported allergy identifies shared and allergy-specific susceptibility loci

(2013) David A Hinds et al.   NATURE GENETICS

Meta-analysis of genome-wide association studies identifies ten loci influencing allergic sensitization

(2013) Klaus Bønnelykke et al.   NATURE GENETICS

The NHGRI GWAS Catalog, a curated resource of SNP-trait associations

(2013) Danielle Welter et al.   NUCLEIC ACIDS RESEARCH

Soluble IL7R  potentiates IL-7 bioactivity and promotes autoimmunity

(2013) W. Lundstrom et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Selection of Self-Reactive T Cells in the Thymus

(2012) Gretta L. Stritesky et al.   Annual Review of Immunology

Does “autoreactivity” play a role in atopic dermatitis?

(2012) Ting Seng Tang et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Environmental factors and risk of developing paediatric inflammatory bowel disease — A population based study 2007–2009

(2012) Christian Jakobsen et al.   Journal of Crohns & Colitis

Transgenic Overexpression of G5PR That Is Normally Augmented in Centrocytes Impairs the Enrichment of High-Affinity Antigen-Specific B Cells, Increases Peritoneal B-1a Cells, and Induces Autoimmunity in Aged Female Mice

(2012) M. Kitabatake et al.   JOURNAL OF IMMUNOLOGY

The use of the twin model to investigate the genetics and epigenetics of skin diseases with genomic, transcriptomic and methylation data

(2012) V. Bataille et al.   JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease

(2012) Luke Jostins et al.   NATURE

An integrated encyclopedia of DNA elements in the human genome

(2012)   NATURE

Bayesian refinement of association signals for 14 loci in 3 common diseases

(2012) Julian B Maller et al.   NATURE GENETICS

Genome-wide association study identifies eight new susceptibility loci for atopic dermatitis in the Japanese population

(2012) Tomomitsu Hirota et al.   NATURE GENETICS

Mapping cis- and trans-regulatory effects across multiple tissues in twins

(2012) Elin Grundberg et al.   NATURE GENETICS

Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity

(2012) Lam C Tsoi et al.   NATURE GENETICS

Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traits

(2012) Jian Yang et al.   NATURE GENETICS

Systematic Localization of Common Disease-Associated Variation in Regulatory DNA

(2012) M. T. Maurano et al.   SCIENCE

IL-7 in human health and disease

(2012) Wangko Lundström et al.   SEMINARS IN IMMUNOLOGY

Clan Genomics and the Complex Architecture of Human Disease

(2011) James R. Lupski et al.   CELL

Transethnic meta-analysis of genomewide association studies

(2011) Andrew P. Morris   GENETIC EPIDEMIOLOGY

A genome-wide meta-analysis of genetic variants associated with allergic rhinitis and grass sensitization and their interaction with birth order

(2011) Adaikalavan Ramasamy et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Reversal of atopic dermatitis with narrow-band UVB phototherapy and biomarkers for therapeutic response

(2011) Suzanne Tintle et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

A genome-wide association study of plasma total IgE concentrations in the Framingham Heart Study

(2011) Mark Granada et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Identification of IL6R and chromosome 11q13.5 as risk loci for asthma

(2011) Manuel AR Ferreira et al.   LANCET

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

(2011) Stephen Sawcer et al.   NATURE

Genome-wide association study identifies two new susceptibility loci for atopic dermatitis in the Chinese Han population

(2011) Liang-Dan Sun et al.   NATURE GENETICS

Genome-wide association study identifies three new susceptibility loci for adult asthma in the Japanese population

(2011) Tomomitsu Hirota et al.   NATURE GENETICS

Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis

(2011) Lavinia Paternoster et al.   NATURE GENETICS

Filaggrin Mutations Associated with Skin and Allergic Diseases

(2011) Alan D. Irvine et al.   NEW ENGLAND JOURNAL OF MEDICINE

Genome-Wide Association Study Identifies HLA-DP as a Susceptibility Gene for Pediatric Asthma in Asian Populations

(2011) Emiko Noguchi et al.   PLoS Genetics

A Genome-Wide Meta-Analysis of Six Type 1 Diabetes Cohorts Identifies Multiple Associated Loci

(2011) Jonathan P. Bradfield et al.   PLoS Genetics

Ets1 blocks terminal differentiation of keratinocytes and induces expression of matrix metalloproteases and innate immune mediators

(2010) P. Nagarajan et al.   JOURNAL OF CELL SCIENCE

The NIH Roadmap Epigenomics Mapping Consortium

(2010) Bradley E Bernstein et al.   NATURE BIOTECHNOLOGY

A Large-Scale, Consortium-Based Genomewide Association Study of Asthma

(2010) Miriam F. Moffatt et al.   NEW ENGLAND JOURNAL OF MEDICINE

Langerhans cells in innate defense against pathogens

(2010) Marein A.W.P. de Jong et al.   TRENDS IN IMMUNOLOGY

Common Inherited Variation in Mitochondrial Genes Is Not Enriched for Associations with Type 2 Diabetes or Related Glycemic Traits

(2010) Ayellet V. Segrè et al.   PLoS Genetics

Genome-wide Association Analysis Identifies PDE4D as an Asthma-Susceptibility Gene

(2009) Blanca E. Himes et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Meta-analysis of filaggrin polymorphisms in eczema and asthma: Robust risk factors in atopic disease

(2009) Elke Rodríguez et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

A common variant on chromosome 11q13 is associated with atopic dermatitis

(2009) Jorge Esparza-Gordillo et al.   NATURE GENETICS

Variants ofDENND1BAssociated with Asthma in Children

(2009) Patrick M.A. Sleiman et al.   NEW ENGLAND JOURNAL OF MEDICINE

Impaired TH17 cell differentiation in subjects with autosomal dominant hyper-IgE syndrome

(2008) Joshua D. Milner et al.   NATURE