Hepcidin knockout mice spontaneously develop chronic pancreatitis owing to cytoplasmic iron overload in acinar cells

Iron metabolism and related genetic diseases: A cleared land, keeping mysteries

(2016) Pierre Brissot et al.   JOURNAL OF HEPATOLOGY

Organ iron accumulation in chronically transfused children with sickle cell anaemia: baseline results from the TWiTCH trial

(2015) John C. Wood et al.   BRITISH JOURNAL OF HAEMATOLOGY

SLC39A14 Is Required for the Development of Hepatocellular Iron Overload in Murine Models of Hereditary Hemochromatosis

(2015) Supak Jenkitkasemwong et al.   Cell Metabolism

Ironing out Ferroportin

(2015) Hal Drakesmith et al.   Cell Metabolism

Genetics, Genetic Testing, and Management of Hemochromatosis: 15 Years Since Hepcidin

(2015) Antonello Pietrangelo   GASTROENTEROLOGY

Differing impact of the deletion of hemochromatosis-associated molecules HFE and transferrin receptor-2 on the iron phenotype of mice lacking bone morphogenetic protein 6 or hemojuvelin

(2015) Chloé Latour et al.   HEPATOLOGY

Resistance of Ferroportin to Hepcidin Binding causes Exocrine Pancreatic Failure and Fatal Iron Overload

(2014) Sandro Altamura et al.   Cell Metabolism

Hepcidin knockout mice fed with iron-rich diet develop chronic liver injury and liver fibrosis due to lysosomal iron overload

(2014) Mariia Lunova et al.   JOURNAL OF HEPATOLOGY

Pancreatic iron and fat assessment by MRI-R2* in patients with iron overload diseases

(2014) Charlotte D. Pfeifer et al.   JOURNAL OF MAGNETIC RESONANCE IMAGING

The pathophysiology and pharmacology of hepcidin

(2014) Piotr Ruchala et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Tissue iron evaluation in chronically transfused children shows significant levels of iron loading at a very young age

(2013) Vasilios Berdoukas et al.   AMERICAN JOURNAL OF HEMATOLOGY

Chronic pancreatitis: role of oxidative stress and antioxidants

(2013) P. Bhardwaj et al.   FREE RADICAL RESEARCH

ZIP14 and DMT1 in the liver, pancreas, and heart are differentially regulated by iron deficiency and overload: implications for tissue iron uptake in iron-related disorders

(2013) H. Nam et al.   HAEMATOLOGICA

Hepatocyte divalent metal-ion transporter-1 is dispensable for hepatic iron accumulation and non-transferrin-bound iron uptake in mice

(2013) Chia-Yu Wang et al.   HEPATOLOGY

CHOP-mediated hepcidin suppression modulates hepatic iron load

(2013) Katrin Mueller et al.   JOURNAL OF PATHOLOGY

Hepcidin regulates intrarenal iron handling at the distal nephron

(2013) Boualem Moulouel et al.   KIDNEY INTERNATIONAL

Systemic Iron Homeostasis

(2013) Tomas Ganz   PHYSIOLOGICAL REVIEWS

Non-HFE hemochromatosis: Pathophysiological and diagnostic aspects

(2013) Edouard Bardou-Jacquet et al.   Clinics and Research in Hepatology and Gastroenterology

Hepatic Iron Deposition Does Not Predict Extrahepatic Iron Loading in Mouse Models of Hereditary Hemochromatosis

(2012) V. Nathan Subramaniam et al.   AMERICAN JOURNAL OF PATHOLOGY

Physiologic implications of metal-ion transport by ZIP14 and ZIP8

(2012) Supak Jenkitkasemwong et al.   BIOMETALS

Alterations in the redox state and liver damage: Hints from the EASL Basic School of Hepatology

(2012) Gianluca Tell et al.   JOURNAL OF HEPATOLOGY

Iron Overload in Human Disease

(2012) Robert E. Fleming et al.   NEW ENGLAND JOURNAL OF MEDICINE

Hsp72 Overexpression Accelerates the Recovery from Caerulein-Induced Pancreatitis

(2012) Mariia Lunova et al.   PLoS One

Liver iron and serum ferritin levels are misleading for estimating cardiac, pancreatic, splenic and total body iron load in thalassemia patients: factors influencing the heterogenic distribution of excess storage iron in organs as identified by MRI T2*

(2012) Annita Kolnagou et al.   TOXICOLOGY MECHANISMS AND METHODS

Knockout Mouse Models of Iron Homeostasis

(2011) Robert E. Fleming et al.   Annual Review of Nutrition

Functions of Autophagy in Hepatic and Pancreatic Physiology and Disease

(2011) Mark J. Czaja   GASTROENTEROLOGY

Iron-Chelating Therapy for Transfusional Iron Overload

(2011) Gary M. Brittenham   NEW ENGLAND JOURNAL OF MEDICINE

Pancreatic exocrine function and cardiac iron in patients with iron overload and with thalassemia

(2011) Jin Yamamura et al.   PEDIATRIC BLOOD & CANCER

Two to Tango: Regulation of Mammalian Iron Metabolism

(2010) Matthias W. Hentze et al.   CELL

Hereditary Hemochromatosis: Pathogenesis, Diagnosis, and Treatment

(2010) Antonello Pietrangelo   GASTROENTEROLOGY

Lack of the bone morphogenetic protein BMP6 induces massive iron overload

(2009) Delphine Meynard et al.   NATURE GENETICS

BMP6 is a key endogenous regulator of hepcidin expression and iron metabolism

(2009) Billy Andriopoulos Jr et al.   NATURE GENETICS

Keratin Mutation Predisposes to Mouse Liver Fibrosis and Unmasks Differential Effects of the Carbon Tetrachloride and Thioacetamide Models

(2008) Pavel Strnad et al.   GASTROENTEROLOGY