CHOP-mediated hepcidin suppression modulates hepatic iron load

Liver hepcidin mRNA expression is inappropriately low in alcoholic patients compared with healthy controls

(2012) Luís Costa-Matos et al.   EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY

Hepatic activation of IKK/NFκB signaling induces liver fibrosis via macrophage-mediated chronic inflammation

(2012) Yoshiaki Sunami et al.   HEPATOLOGY

Inhibition of hepcidin transcription by growth factors

(2012) Julia B. Goodnough et al.   HEPATOLOGY

Hepcidin is localised in gastric parietal cells, regulates acid secretion and is induced byHelicobacter pyloriinfection

(2011) Peggy Schwarz et al.   GUT

An unrestrained proinflammatory M1 macrophage population induced by iron impairs wound healing in humans and mice

(2011) Anca Sindrilaru et al.   JOURNAL OF CLINICAL INVESTIGATION

Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress

(2011) Ira Tabas et al.   NATURE CELL BIOLOGY

Hepatocarcinogenesis in Hepatitis C: HCV Shrewdly Exacerbates Oxidative Stress by Modulating both Production and Scavenging of Reactive Oxygen Species

(2011) Hidetake Fujinaga et al.   ONCOLOGY

Pathology of Hepatic Iron Overload

(2011) Yves Deugnier et al.   SEMINARS IN LIVER DISEASE

Iron trafficking and metabolism in macrophages: contribution to the polarized phenotype

(2011) Gaetano Cairo et al.   TRENDS IN IMMUNOLOGY

Iron disorders of genetic origin: a changing world

(2011) Pierre Brissot et al.   TRENDS IN MOLECULAR MEDICINE

Hepcidin and Disorders of Iron Metabolism

(2010) Tomas Ganz et al.   Annual Review of Medicine

Stress Signaling in the Methionine-Choline–Deficient Model of Murine Fatty Liver Disease

(2010) Russell K. Soon et al.   GASTROENTEROLOGY

No evidence of the unfolded protein response in patients with chronic hepatitis C virus infection

(2010) Stuart McPherson et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

ATF4 and the integrated stress response are induced by ethanol and cytochrome P450 2E1 in human hepatocytes

(2010) Laurent Magne et al.   JOURNAL OF HEPATOLOGY

Hepcidin in human iron disorders: Therapeutic implications

(2010) Antonello Pietrangelo   JOURNAL OF HEPATOLOGY

Endoplasmic reticulum stress in liver disease

(2010) Harmeet Malhi et al.   JOURNAL OF HEPATOLOGY

Hepcidin, the iron watcher

(2009) Lydie Viatte et al.   BIOCHIMIE

Targeting liver fibrosis: Strategies for development and validation of antifibrotic therapies

(2009) Yury Popov et al.   HEPATOLOGY

Reduced serum hepcidin levels in patients with chronic hepatitis C

(2009) Domenico Girelli et al.   JOURNAL OF HEPATOLOGY

Serum hepcidin levels are related to the severity of liver histological lesions in chronic hepatitis C

(2009) E. Tsochatzis et al.   JOURNAL OF VIRAL HEPATITIS

ER Stress-Inducible Factor CHOP Affects the Expression of Hepcidin by Modulating C/EBPalpha Activity

(2009) Susana J. Oliveira et al.   PLoS One

ER Stress Controls Iron Metabolism Through Induction of Hepcidin

(2009) C. Vecchi et al.   SCIENCE

Keratin Mutation Predisposes to Mouse Liver Fibrosis and Unmasks Differential Effects of the Carbon Tetrachloride and Thioacetamide Models

(2008) Pavel Strnad et al.   GASTROENTEROLOGY

Liver Iron, HFE Gene Mutations, and Hepatocellular Carcinoma Occurrence in Patients With Cirrhosis

(2007) Pierre Nahon et al.   GASTROENTEROLOGY

Hepatitis C Virus–Induced Reactive Oxygen Species Raise Hepatic Iron Level in Mice by Reducing Hepcidin Transcription

(2007) Sohji Nishina et al.   GASTROENTEROLOGY

Activation and Dysregulation of the Unfolded Protein Response in Nonalcoholic Fatty Liver Disease

(2007) Puneet Puri et al.   GASTROENTEROLOGY