Mechanistic insights into the nickel-dependent allosteric response of the Helicobacter pylori NikR transcription factor

Delineating the conformational landscape of the adenosine A2A receptor during G protein coupling

(2021) Shuya Kate Huang et al.   CELL

Molecular Hydrogen Metabolism: a Widespread Trait of Pathogenic Bacteria and Protists

(2020) Stéphane L. Benoit et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Substrate-Based Allosteric Regulation of a Homodimeric Enzyme

(2019) Pedram Mehrabi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Allosteric control of metal-responsive transcriptional regulators in bacteria

(2019) Karina A. Baksh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The impact of a His-tag on DNA binding by RNA polymerase alpha-C-terminal domain from Helicobacter pylori

(2019) Navjit K. Paul et al.   PROTEIN EXPRESSION AND PURIFICATION

BeStSel: a web server for accurate protein secondary structure prediction and fold recognition from the circular dichroism spectra

(2018) András Micsonai et al.   NUCLEIC ACIDS RESEARCH

Mechanistic insights into allosteric regulation of the A2A adenosine G protein-coupled receptor by physiological cations

(2018) Libin Ye et al.   Nature Communications

Tuning site-specific dynamics to drive allosteric activation in a pneumococcal zinc uptake regulator

(2018) Daiana A Capdevila et al.   eLife

Metallochaperones and metalloregulation in bacteria

(2017) Daiana A. Capdevila et al.   Essays in Biochemistry

Survival of Helicobacter pylori in gastric acidic territory

(2017) Shamshul Ansari et al.   HELICOBACTER

Metal homeostasis and resistance in bacteria

(2017) Pete Chandrangsu et al.   NATURE REVIEWS MICROBIOLOGY

Entropy redistribution controls allostery in a metalloregulatory protein

(2017) Daiana A. Capdevila et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The role of dimer asymmetry and protomer dynamics in enzyme catalysis

(2017) Tae Hun Kim et al.   SCIENCE

Comprehensive mapping of the Helicobacter pylori NikR regulon provides new insights in bacterial nickel responses

(2017) Andrea Vannini et al.   Scientific Reports

Surface plasmon resonance and isothermal titration calorimetry to monitor the Ni(II)-dependent binding of Helicobacter pylori NikR to DNA

(2016) Edoardo Fabini et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Transition Metals and Virulence in Bacteria

(2016) Lauren D. Palmer et al.   Annual Review of Genetics

Protein Ensembles: How Does Nature Harness Thermodynamic Fluctuations for Life? The Diverse Functional Roles of Conformational Ensembles in the Cell

(2016) Guanghong Wei et al.   CHEMICAL REVIEWS

The Role of Protein Loops and Linkers in Conformational Dynamics and Allostery

(2016) Elena Papaleo et al.   CHEMICAL REVIEWS

On the interaction of Helicobacter pylori NikR, a Ni(II)-responsive transcription factor, with the urease operator: in solution and in silico studies

(2015) Luca Mazzei et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Nickel-responsive regulation of two novel Helicobacter pylori NikR-targeted genes

(2015) M. D. Jones et al.   Metallomics

Accurate secondary structure prediction and fold recognition for circular dichroism spectroscopy

(2015) András Micsonai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Metal Preferences and Metallation

(2014) Andrew W. Foster et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The ensemble nature of allostery

(2014) Hesam N. Motlagh et al.   NATURE

Physical Characterization of the Manganese-Sensing Pneumococcal Surface Antigen Repressor from Streptococcus pneumoniae

(2013) John P. Lisher et al.   BIOCHEMISTRY

Helicobacter pylori-induced gastric inflammation and gastric cancer

(2013) Fei Wang et al.   CANCER LETTERS

Allosteric Inhibition of a Zinc-Sensing Transcriptional Repressor: Insights into the Arsenic Repressor (ArsR) Family

(2013) Gregory C. Campanello et al.   JOURNAL OF MOLECULAR BIOLOGY

Antimicrobial activity of metals: mechanisms, molecular targets and applications

(2013) Joseph A. Lemire et al.   NATURE REVIEWS MICROBIOLOGY

Nonspecific Interactions Between Escherichia coli NikR and DNA Are Critical for Nickel-Activated DNA Binding

(2012) Sandra Krecisz et al.   BIOCHEMISTRY

Dissecting the role of DNA sequence in Helicobacter pylori NikR/DNA recognition

(2012) Sarah E. Evans et al.   DALTON TRANSACTIONS

Nutritional immunity: transition metals at the pathogen–host interface

(2012) M. Indriati Hood et al.   NATURE REVIEWS MICROBIOLOGY

Ni(II) coordination to mixed sites modulates DNA binding of HpNikR via a long-range effect

(2012) A. L. West et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Metal site occupancy and allosteric switching in bacterial metal sensor proteins

(2011) Alfredo J. Guerra et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Metalloregulatory proteins: Metal selectivity and allosteric switching

(2011) Hermes Reyes-Caballero et al.   BIOPHYSICAL CHEMISTRY

Recent advances in Helicobacter pylori pathogenesis

(2011) Michal Sibony et al.   CURRENT OPINION IN GASTROENTEROLOGY

Holo-Ni2+Helicobacter pylori NikR contains four square-planar nickel-binding sites at physiological pH

(2011) Stefano Benini et al.   DALTON TRANSACTIONS

Helicobacter pyloriNikR Protein Exhibits Distinct Conformations When Bound to Different Promoters

(2011) Erin L. Benanti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanisms of nickel toxicity in microorganisms

(2011) Lee Macomber et al.   Metallomics

Hierarchical regulation of the NikR-mediated nickel response in Helicobacter pylori

(2011) Cécile Muller et al.   NUCLEIC ACIDS RESEARCH

Dynamic Allostery: Linkers Are Not Merely Flexible

(2011) Buyong Ma et al.   STRUCTURE

Structural Basis of Low-Affinity Nickel Binding to the Nickel-Responsive Transcription Factor NikR fromEscherichia coli

(2010) Christine M. Phillips et al.   BIOCHEMISTRY

Computational Study of the DNA-Binding ProteinHelicobacter pyloriNikR: The Role of Ni2+22 Francesco Musiani and Branimir Bertoša contributed equally to the simulations presented here.

(2010) Francesco Musiani et al.   Journal of Chemical Theory and Computation

Holo-Ni(II)HpNikR Is an Asymmetric Tetramer Containing Two Different Nickel-Binding Sites

(2010) Abby L. West et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Coordinating intracellular nickel–metal-site structure-function relationships and the NikR and RcnR repressors

(2010) Jeffrey S. Iwig et al.   NATURAL PRODUCT REPORTS

Structural and mechanistic insights into Helicobacter pylori NikR activation

(2010) C. Bahlawane et al.   NUCLEIC ACIDS RESEARCH

pH-Responsive DNA-Binding Activity of Helicobacter pylori NikR†

(2009) Yanjie Li et al.   BIOCHEMISTRY

Helicobacter pyloriNikR’s Interaction with DNA: A Two-Tiered Mode of Recognition†

(2009) Nuvjeevan S. Dosanjh et al.   BIOCHEMISTRY

Characterization of NikR-responsive promoters of urease and metal transport genes of Helicobacter mustelae

(2009) Jeroen Stoof et al.   BIOMETALS

Coordination Chemistry of Bacterial Metal Transport and Sensing

(2009) Zhen Ma et al.   CHEMICAL REVIEWS

Hydrogen and Nickel Metabolism inHelicobacterSpecies

(2008) Stéphane L. Benoit et al.   Annals of the New York Academy of Sciences

Structural Basis of the Metal Specificity for Nickel Regulatory Protein NikR†,‡

(2008) Christine M. Phillips et al.   BIOCHEMISTRY

Metal ions in biological catalysis: from enzyme databases to general principles

(2008) Claudia Andreini et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

High-Affinity Ni2+ Binding Selectively Promotes Binding of Helicobacter pylori NikR to Its Target Urease Promoter

(2008) Barbara Zambelli et al.   JOURNAL OF MOLECULAR BIOLOGY