C5aR antagonist inhibits LPS-induced inflammation in human gingival fibroblasts via NF-κB and MAPK signaling pathways

Inhibition of complement C5a receptor protects lung cells and tissues against lipopolysaccharide-induced injury via blocking pyroptosis

(2021) Renying Wang et al.   Aging-US

Human gingival fibroblasts: Isolation, characterization, and evaluation of CD146 expression

(2021) Samira Diar-Bakirly et al.   SAUDI JOURNAL OF BIOLOGICAL SCIENCES

Preclinical Pharmacokinetics of Complement C5a Receptor Antagonists PMX53 and PMX205 in Mice

(2020) Vinod Kumar et al.   ACS Omega

Current concepts in the management of periodontitis

(2020) TaeHyun Kwon et al.   INTERNATIONAL DENTAL JOURNAL

Anti-Inflammatory Effect of Sulforaphane on LPS-Activated Microglia Potentially through JNK/AP-1/NF-κB Inhibition and Nrf2/HO-1 Activation

(2019) Lalita Subedi et al.   Cells

Oridonin inhibits LPS-induced inflammation in human gingival fibroblasts by activating PPARγ

(2019) Tianliang Yu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Porcine Beta-Defensin 2 Provides Protection Against Bacterial Infection by a Direct Bactericidal Activity and Alleviates Inflammation via Interference With the TLR4/NF-κB Pathway

(2019) Chao Huang et al.   Frontiers in Immunology

Complement activation sustains neuroinflammation and deteriorates adult neurogenesis and spatial memory impairment in rat hippocampus following sleep deprivation

(2019) Meetu Wadhwa et al.   BRAIN BEHAVIOR AND IMMUNITY

Quercetin Inhibits Inflammatory Response Induced by LPS from Porphyromonas gingivalis in Human Gingival Fibroblasts via Suppressing NF-κB Signaling Pathway

(2019) Gang Xiong et al.   Biomed Research International

Anti-inflammatory action of Athyrium multidentatum extract suppresses the LPS-induced TLR4 signaling pathway

(2018) Xiong-Zhe Han et al.   JOURNAL OF ETHNOPHARMACOLOGY

Prolyl hydroxylases positively regulated LPS-induced inflammation in human gingival fibroblasts via TLR4/MyD88-mediated AKT/NF-κB and MAPK pathways

(2018) Lingling Shang et al.   CELL PROLIFERATION

Fibroblasts and Mesenchymal Stromal/Stem Cells Are Phenotypically Indistinguishable

(2016) Ryan A. Denu et al.   ACTA HAEMATOLOGICA

Baicalin inhibits toll-like receptor 2/4 expression and downstream signaling in rat experimental periodontitis

(2016) Jun-Yi Sun et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Prediabetes Enhances Periodontal Inflammation Consistent With Activation of Toll-Like Receptor–Mediated Nuclear Factor-κB Pathway in Rats

(2016) Yanli Huang et al.   JOURNAL OF PERIODONTOLOGY

Tormentic acid inhibits LPS-induced inflammatory response in human gingival fibroblasts via inhibition of TLR4-mediated NF-κB and MAPK signalling pathway

(2015) Cong-Xiang Jian et al.   ARCHIVES OF ORAL BIOLOGY

Complement C5a-C5aR interaction enhances MAPK signaling pathway activities to mediate renal injury in trichloroethylene sensitized BALB/c mice

(2015) Jia-xiang Zhang et al.   JOURNAL OF APPLIED TOXICOLOGY

Update on Prevalence of Periodontitis in Adults in the United States: NHANES 2009 to 2012

(2015) Paul I. Eke et al.   JOURNAL OF PERIODONTOLOGY

Alternative mRNA transcription, processing, and translation: insights from RNA sequencing

(2015) Eleonora de Klerk et al.   TRENDS IN GENETICS

Gingiva as a Source of Stem Cells with Therapeutic Potential

(2013) Benjamin P.J. Fournier et al.   STEM CELLS AND DEVELOPMENT

Modulation of host cell signaling pathways as a therapeutic approach in periodontal disease

(2012) João Antonio Chaves de Souza et al.   Journal of Applied Oral Science

Oral treatment with complement factor C5a receptor (CD88) antagonists inhibits experimental periodontitis in rats

(2011) T. Breivik et al.   JOURNAL OF PERIODONTAL RESEARCH

Complement and periodontitis

(2010) George Hajishengallis   BIOCHEMICAL PHARMACOLOGY

Complement component 5a (C5a)

(2009) Helga D. Manthey et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

The role of the anaphylatoxins in health and disease

(2009) Andreas Klos et al.   MOLECULAR IMMUNOLOGY

Cytokines That Promote Periodontal Tissue Destruction

(2008) Dana Graves   JOURNAL OF PERIODONTOLOGY