Prolyl hydroxylases positively regulated LPS-induced inflammation in human gingival fibroblasts via TLR4/MyD88-mediated AKT/NF-κB and MAPK pathways

Scutellarin suppresses neuroinflammation via the inhibition of the AKT/NF-κB and p38/JNK pathway in LPS-induced BV-2 microglial cells

(2018) Pengtao You et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Toll-like receptors: Significance, ligands, signaling pathways, and functions in mammals

(2017) Mallenahally Kusha Vidya et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

Haematopoietic prolyl hydroxylase-1 deficiency promotes M2 macrophage polarization and is both necessary and sufficient to protect against experimental colitis

(2017) Sophie Van Welden et al.   JOURNAL OF PATHOLOGY

Metformin Inhibits Porphyromonas gingivalis Lipopolysaccharide-Influenced Inflammatory Response in Human Gingival Fibroblasts via Regulating Activating Transcription Factor-3 Expression

(2017) Wenyan Kang et al.   JOURNAL OF PERIODONTOLOGY

Farrerol inhibits IL-6 and IL-8 production in LPS-stimulated human gingival fibroblasts by suppressing PI3K/AKT/NF-κB signaling pathway

(2016) Qian Wang et al.   ARCHIVES OF ORAL BIOLOGY

Lipopolysaccharide and IL-1β coordinate a synergy on cytokine production by upregulating MyD88 expression in human gingival fibroblasts

(2016) Colleen W. Brinson et al.   MOLECULAR IMMUNOLOGY

Toll-like receptors: Activation, signalling and transcriptional modulation

(2015) Dominic De Nardo   CYTOKINE

Prolyl-4-hydroxylase Domain Protein 2 Controls NF-κB/p65 Transactivation and Enhances the Catabolic Effects of Inflammatory Cytokines on Cells of the Nucleus Pulposus

(2015) Jun Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Acanthoic Acid Inhibits LPS-Induced Inflammatory Response in Human Gingival Fibroblasts

(2014) Cai Wei et al.   INFLAMMATION

Anti-inflammatory activity of fisetin in human gingival fibroblasts treated with lipopolysaccharide

(2014) Gloria Gutiérrez-Venegas et al.   JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH

Bacterial invasion and persistence: critical events in the pathogenesis of periodontitis?

(2014) S. Ji et al.   JOURNAL OF PERIODONTAL RESEARCH

Uncovering the molecular networks in periodontitis

(2014) Fábio Trindade et al.   Proteomics Clinical Applications

The Hypoxia-Inducible Factor Pathway, Prolyl Hydroxylase Domain Protein Inhibitors, and Their Roles in Bone Repair and Regeneration

(2014) Lihong Fan et al.   Biomed Research International

Hydroxylase-dependent regulation of the NF-κB pathway

(2013) Carsten C. Scholz et al.   BIOLOGICAL CHEMISTRY

Targeting the HIF pathway in inflammation and immunity

(2013) Carsten C Scholz et al.   CURRENT OPINION IN PHARMACOLOGY

EGLN3 Inhibition of NF- B Is Mediated by Prolyl Hydroxylase-Independent Inhibition of I B Kinase   Ubiquitination

(2013) J. Fu et al.   MOLECULAR AND CELLULAR BIOLOGY

Hypoxia Modulates Infection of Epithelial Cells by Pseudomonas aeruginosa

(2013) Bettina Schaible et al.   PLoS One

Toll-Like Receptor Signaling

(2013) K.-H. Lim et al.   Cold Spring Harbor Perspectives in Biology

NF-κB as a Target for Modulating Inflammatory Responses

(2012) Chiara Gasparini et al.   CURRENT PHARMACEUTICAL DESIGN

Prolyl Hydroxylase 3 (PHD3) Modulates Catabolic Effects of Tumor Necrosis Factor-α (TNF-α) on Cells of the Nucleus Pulposus through Co-activation of Nuclear Factor κB (NF-κB)/p65 Signaling

(2012) Nobuyuki Fujita et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lipopolysaccharide and Hypoxia-Induced HIF-1 Activation in Human Gingival Fibroblasts

(2011) Jing-Ping Li et al.   JOURNAL OF PERIODONTOLOGY

The Hydroxylase Inhibitor Dimethyloxallyl Glycine Attenuates Endotoxic Shock Via Alternative Activation of Macrophages and IL-10 Production by B1 Cells

(2011) Emily Hams et al.   SHOCK

Inhibition of Prolyl Hydroxylase Domain-Containing Protein Suppressed Lipopolysaccharide-Induced TNF-α Expression

(2009) Kotaro Takeda et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Human gingival fibroblasts are critical in sustaining inflammation in periodontal disease

(2009) Toshiaki Ara et al.   JOURNAL OF PERIODONTAL RESEARCH

Hypoxia. Regulation of NFκB signalling during inflammation: the role of hydroxylases

(2009) Kathryn M Oliver et al.   ARTHRITIS RESEARCH & THERAPY

The Nuclear Factor NF- B Pathway in Inflammation

(2009) T. Lawrence   Cold Spring Harbor Perspectives in Biology

Oxygen Sensing by Metazoans: The Central Role of the HIF Hydroxylase Pathway

(2008) William G. Kaelin et al.   MOLECULAR CELL

The Hydroxylase Inhibitor Dimethyloxalylglycine Is Protective in a Murine Model of Colitis

(2007) Eoin P. Cummins et al.   GASTROENTEROLOGY