Role of Sirtuins in the Pathogenesis of Rheumatoid Arthritis

Resveratrol and Immune Cells: A Link to Improve Human Health

(2022) Alessio Alesci et al.   MOLECULES

Flavonoids as Sirtuin Modulators

(2022) Fatma Sezer Şenol Deniz et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Sirt5 Deficiency Causes Posttranslational Protein Malonylation and Dysregulated Cellular Metabolism in Chondrocytes Under Obesity Conditions

(2021) Shouan Zhu et al.   Cartilage

Sirtuin-7 as a Novel Therapeutic Target in Vascular Smooth Muscle Cell Proliferation and Remodeling

(2021) Kimio Satoh   CIRCULATION JOURNAL

Role of mitochondrial sirtuins in rheumatoid arthritis

(2021) Muhmmad Zahid Hussain et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Emerging roles of Sirtuin 2 in cardiovascular diseases

(2021) Arushi Taneja et al.   FASEB JOURNAL

Regulation of Sirt1 on energy metabolism and immune response in rheumatoid arthritis

(2021) Yi-jin Wu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

SIRT1: A Potential Therapeutic Target in Autoimmune Diseases

(2021) Pan Shen et al.   Frontiers in Immunology

The Effect of Ketogenic Diet on Inflammatory Arthritis and Cardiovascular Health in Rheumatic Conditions: A Mini Review

(2021) Jacopo Ciaffi et al.   Frontiers in Medicine

Sirtuin 5 deficiency increases disease severity in rats with adjuvant-induced arthritis

(2020) Ni Zhang et al.   Cellular & Molecular Immunology

Molecular mechanisms underlying rheumatoid arthritis and cancer development and treatment

(2020) Susan Morand et al.   Future Oncology

Resveratrol promotes osteogenesis via activating SIRT1/FoxO1 pathway in osteoporosis mice

(2020) Yixuan Jiang et al.   LIFE SCIENCES

Cancer and Rheumatoid Arthritis

(2020) Xerxes Pundole et al.   RHEUMATIC DISEASE CLINICS OF NORTH AMERICA

Small Molecule Inhibitors in the Treatment of Rheumatoid Arthritis and Beyond: Latest Updates and Potential Strategy for Fighting COVID-19

(2020) Magdalena Massalska et al.   Cells

Malignancy and rheumatoid arthritis: Epidemiology, risk factors and management

(2019) Diederik De Cock et al.   BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY

Influence of Resveratrol on the Immune Response

(2019) Malaguarnera   Nutrients

Systemic rheumatic diseases: From biological agents to small molecules

(2019) Piercarlo Sarzi-Puttini et al.   AUTOIMMUNITY REVIEWS

Long non-coding RNA PVT1 knockdown suppresses fibroblast-like synoviocyte inflammation and induces apoptosis in rheumatoid arthritis through demethylation of sirt6

(2019) Chun-Wang Zhang et al.   Journal of Biological Engineering

Resveratrol ameliorates rheumatoid arthritis via activation of SIRT1‐Nrf2 signaling pathway

(2019) Gaoyuan Wang et al.   BIOFACTORS

SIRT1 inhibits rheumatoid arthritis fibroblast-like synoviocyte aggressiveness and inflammatory response via suppressing NF-κB pathway

(2018) Guoqing Li et al.   BIOSCIENCE REPORTS

Rheumatoid arthritis and lymphoma: Incidence, pathogenesis, biology, and outcome

(2018) Alina Klein et al.   HEMATOLOGICAL ONCOLOGY

Small Molecules as SIRT Modulators

(2018) Xinfa Bai et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Resveratrol Alleviates Rheumatoid Arthritis via Reducing ROS and Inflammation, Inhibiting MAPK Signaling Pathways, and Suppressing Angiogenesis

(2018) Guliang Yang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Myeloid sirtuin 6 deficiency accelerates experimental rheumatoid arthritis by enhancing macrophage activation and infiltration into synovium

(2018) Seong Ji Woo et al.   EBioMedicine

Establishment of an in vitro three-dimensional model for cartilage damage in rheumatoid arthritis

(2017) Yvonne Peck et al.   Journal of Tissue Engineering and Regenerative Medicine

Nutrition and fasting mimicking diets in the prevention and treatment of autoimmune diseases and immunosenescence

(2017) In Young Choi et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

SIRT5 Desuccinylates and Activates Pyruvate Kinase M2 to Block Macrophage IL-1β Production and to Prevent DSS-Induced Colitis in Mice

(2017) Fang Wang et al.   Cell Reports

SIRT1/Adenosine Monophosphate-Activated Protein Kinase α Signaling Enhances Macrophage Polarization to an Anti-inflammatory Phenotype in Rheumatoid Arthritis

(2017) So Youn Park et al.   Frontiers in Immunology

Sirtuins in glucose and lipid metabolism

(2016) Xin Ye et al.   Oncotarget

Production of RANKL by Memory B Cells: A Link Between B Cells and Bone Erosion in Rheumatoid Arthritis

(2016) Nida Meednu et al.   Arthritis & Rheumatology

SIRT1 reduces endothelial activation without affecting vascular function in ApoE-/- mice

(2016) Sokrates Stein et al.   Aging-US

Epigenetics in rheumatoid arthritis

(2015) Kerstin Klein et al.   CURRENT OPINION IN RHEUMATOLOGY

The Transcription Factor E4F1 Coordinates CHK1-Dependent Checkpoint and Mitochondrial Functions

(2015) Geneviève Rodier et al.   Cell Reports

Sirtuin 4 Is a Lipoamidase Regulating Pyruvate Dehydrogenase Complex Activity

(2014) Rommel A. Mathias et al.   CELL

Overexpression of Sirtuin 6 Suppresses Inflammatory Responses and Bone Destruction in Mice With Collagen-Induced Arthritis

(2013) Hwa-Suk Lee et al.   ARTHRITIS AND RHEUMATISM

Resveratrol Attenuates the Release of Inflammatory Cytokines from Human Bronchial Smooth Muscle Cells Exposed to Lipoteichoic Acid in Chronic Obstructive Pulmonary Disease

(2013) Jürgen Knobloch et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Sirt2 suppresses inflammatory responses in collagen-induced arthritis

(2013) Jiangtao Lin et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

SIRT5 Regulates the Mitochondrial Lysine Succinylome and Metabolic Networks

(2013) Matthew J. Rardin et al.   Cell Metabolism

The Class III Histone Deacetylase Sirtuin 1 in Immune Suppression and Its Therapeutic Potential in Rheumatoid Arthritis

(2013) Sinyi Kong et al.   Journal of Genetics and Genomics

Sirt1 overexpression protects murine osteoblasts against TNF-α-induced injury in vitro by suppressing the NF-κB signaling pathway

(2012) Wei Huang et al.   ACTA PHARMACOLOGICA SINICA

Sirtuin activators and inhibitors

(2012) José M. Villalba et al.   BIOFACTORS

The Histone Deacetylase SIRT6 Is a Tumor Suppressor that Controls Cancer Metabolism

(2012) Carlos Sebastián et al.   CELL

Seven sirtuins for seven deadly diseases ofaging

(2012) Brian J. Morris   FREE RADICAL BIOLOGY AND MEDICINE

Anti-inflammatory Effects of Resveratrol and Its Potential Use in Therapy of Immune-mediated Diseases

(2012) Urban Švajger et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

SIRT7 links H3K18 deacetylation to maintenance of oncogenic transformation

(2012) Matthew F. Barber et al.   NATURE

SIRT1, a class III histone deacetylase, regulates TNF-α-induced inflammation in human chondrocytes

(2012) M.-H. Moon et al.   OSTEOARTHRITIS AND CARTILAGE

SIRT1 overexpression in the rheumatoid arthritis synovium contributes to proinflammatory cytokine production and apoptosis resistance

(2011) F. Niederer et al.   ANNALS OF THE RHEUMATIC DISEASES

Oxidative stress, glutathione status, sirtuin and cellular stress response in type 2 diabetes

(2011) V. Calabrese et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Sirt1 Is a Regulator of Bone Mass and a Repressor ofSostEncoding for Sclerostin, a Bone Formation Inhibitor

(2011) Einav Cohen-Kfir et al.   ENDOCRINOLOGY

Resveratrol induces apoptosis MH7A human rheumatoid arthritis synovial cells in a sirtuin 1-dependent manner

(2010) Hiroshi Nakayama et al.   RHEUMATOLOGY INTERNATIONAL

Changes of Intestinal Microflora in Patients with Rheumatoid Arthritis during Fasting or a Mediterranean Diet

(2010) Annalena Abendroth et al.   FORSCHENDE KOMPLEMENTARMEDIZIN

Prospective new biological therapies for rheumatoid arthritis

(2009) Ladislav Šenolt et al.   AUTOIMMUNITY REVIEWS

The type III histone deacetylase Sirt1 is essential for maintenance of T cell tolerance in mice

(2009) Jinping Zhang et al.   JOURNAL OF CLINICAL INVESTIGATION

Substrates and Regulation Mechanisms for the Human Mitochondrial Sirtuins Sirt3 and Sirt5

(2008) Christine Schlicker et al.   JOURNAL OF MOLECULAR BIOLOGY

Sirtuins — novel therapeutic targets to treat age-associated diseases

(2008) Siva Lavu et al.   NATURE REVIEWS DRUG DISCOVERY