Combining protein and metabolic engineering to achieve green biosynthesis of 12β-O-Glc-PPD in Saccharomyces cerevisiae

Biocatalysis for Rare Ginsenoside Rh2 Production in High Level with Co-Immobilized UDP-Glycosyltransferase Bs-YjiC Mutant and Sucrose Synthase AtSuSy

(2021) Jianlin Chu et al.   Catalysts

High-level sustainable production of the characteristic protopanaxatriol-type saponins from Panax species in engineered Saccharomyces cerevisiae

(2021) Xiaodong Li et al.   METABOLIC ENGINEERING

Engineering yeast subcellular compartments for increased production of the lipophilic natural products ginsenosides

(2021) Yusong Shi et al.   METABOLIC ENGINEERING

Systematic optimization of the yeast cell factory for sustainable and high efficiency production of bioactive ginsenoside compound K

(2021) Pingping Wang et al.   Synthetic and Systems Biotechnology

Yeast Surface Display for In Vitro Biosynthetic Pathway Reconstruction

(2021) Biaobiao Luo et al.   ACS Synthetic Biology

Biocatalytic synthesis of ginsenoside Rh2 using Arabidopsis thaliana glucosyltransferase-catalyzed coupled reactions

(2020) Yumei Hu et al.   JOURNAL OF BIOTECHNOLOGY

Efficient O-Glycosylation of Triterpenes Enabled by Protein Engineering of Plant Glycosyltransferase UGT74AC1

(2020) Jiao Li et al.   ACS Catalysis

Structural dissection of unnatural ginsenoside-biosynthetic UDP-glycosyltransferase Bs-YjiC from Bacillus subtilis for substrate promiscuity

(2020) Longhai Dai et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Structural and biochemical studies of the glycosyltransferase Bs-YjiC from Bacillus subtilis

(2020) Bing Liu et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Ginsenoside Rb1 as an Anti-Diabetic Agent and Its Underlying Mechanism Analysis

(2019) Ping Zhou et al.   Cells

Cloning and characterization of the β-xylosidase from Dictyoglomus turgidum for high efficient biotransformation of 10-deacetyl-7-xylosltaxol

(2019) Qi Li et al.   BIOORGANIC CHEMISTRY

Oriented efficient biosynthesis of rare ginsenoside Rh2 from PPD by compiling UGT-Yjic mutant with sucrose synthase

(2019) Wang Ma et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Enhancing oleanolic acid production in engineered Saccharomyces cerevisiae

(2018) Yujia Zhao et al.   BIORESOURCE TECHNOLOGY

SWISS-MODEL: homology modelling of protein structures and complexes

(2018) Andrew Waterhouse et al.   NUCLEIC ACIDS RESEARCH

Switching glycosyltransferase UGTBL1 regioselectivity toward polydatin synthesis using a semi-rational design

(2018) Bo Fan et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

SG formation relies on eIF4GI-G3BP interaction which is targeted by picornavirus stress antagonists

(2018) Xiaodan Yang et al.   Cell Discovery

Recent advances in reagent-controlled stereoselective/stereospecific glycosylation

(2018) Hui Yao et al.   CARBOHYDRATE RESEARCH

Enhancement of recombinant BmK AngM1 production in Pichia pastoris by regulating gene dosage, co-expressing with chaperones and fermenting in fed-batch mode

(2017) Qing-Hua Wang et al.   JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH

Exploiting the aglycon promiscuity of glycosyltransferase Bs-YjiC from Bacillus subtilis and its application in synthesis of glycosides

(2017) Longhai Dai et al.   JOURNAL OF BIOTECHNOLOGY

Biosynthesis of plant-derived ginsenoside Rh2 in yeast via repurposing a key promiscuous microbial enzyme

(2017) Yu Zhuang et al.   METABOLIC ENGINEERING

Production of a bioactive unnatural ginsenoside by metabolically engineered yeasts based on a new UDP-glycosyltransferase from Bacillus subtilis

(2017) Huichao Liang et al.   METABOLIC ENGINEERING

Biosynthesis of rare 20( R )-protopanaxadiol/protopanaxatriol type ginsenosides through Escherichia coli engineered with uridine diphosphate glycosyltransferase genes

(2017) Lu Yu et al.   Journal of Ginseng Research

Ror2 signaling regulates Golgi structure and transport through IFT20 for tumor invasiveness

(2017) Michiru Nishita et al.   Scientific Reports

Cloning and Characterization of Ginsenoside-Hydrolyzing β-Glucosidase from Lactobacillus brevis That Transforms Ginsenosides Rb1 and F2 into Ginsenoside Rd and Compound K

(2016) Fei-Liang Zhong et al.   JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY

Ultrastructural Characterization of the Lower Motor System in a Mouse Model of Krabbe Disease

(2016) Valentina Cappello et al.   Scientific Reports

Production of natural products through metabolic engineering of Saccharomyces cerevisiae

(2015) Anastasia Krivoruchko et al.   CURRENT OPINION IN BIOTECHNOLOGY

Ergosteryl-β-glucosidase (Egh1) involved in sterylglucoside catabolism and vacuole formation inSaccharomyces cerevisiae

(2015) Takashi Watanabe et al.   GLYCOBIOLOGY

Production of bioactive ginsenosides Rh2 and Rg3 by metabolically engineered yeasts

(2015) Pingping Wang et al.   METABOLIC ENGINEERING

Characterization of Panax ginseng UDP-Glycosyltransferases Catalyzing Protopanaxatriol and Biosyntheses of Bioactive Ginsenosides F1 and Rh1 in Metabolically Engineered Yeasts

(2015) Wei Wei et al.   Molecular Plant

Stereospecificity of Ginsenoside Rg3 in the Promotion of Cellular Immunity in Hepatoma H22-Bearing Mice

(2014) Rihui Wu et al.   JOURNAL OF FOOD SCIENCE

Metabolic engineering of Saccharomyces cerevisiae for production of ginsenosides

(2013) Zhubo Dai et al.   METABOLIC ENGINEERING

Cloning and Characterization of the Glycoside Hydrolases That Remove Xylosyl Groups from 7-β-xylosyl-10-deacetyltaxol and Its Analogues

(2013) Hai-Li Cheng et al.   MOLECULAR & CELLULAR PROTEOMICS

Engineering flavonoid glycosyltransferases for enhanced catalytic efficiency and extended sugar-donor selectivity

(2013) Hye Soo Kim et al.   PLANTA

Comparing the acceptor promiscuity of a Rosa hybrida glucosyltransferase RhGT1 and an engineered microbial glucosyltransferase OleDPSA toward a small flavonoid library

(2012) Lu Wang et al.   CARBOHYDRATE RESEARCH

Engineering the third wave of biocatalysis

(2012) U. T. Bornscheuer et al.   NATURE

Production of amorphadiene in yeast, and its conversion to dihydroartemisinic acid, precursor to the antimalarial agent artemisinin

(2012) P. J. Westfall et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of aSaccharomyces cerevisiaeGlucosidase That Hydrolyzes Flavonoid Glucosides

(2011) Sabine Schmidt et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

The Cyt P450 Enzyme CYP716A47 Catalyzes the Formation of Protopanaxadiol from Dammarenediol-II During Ginsenoside Biosynthesis in Panax ginseng

(2011) Jung-Yeon Han et al.   PLANT AND CELL PHYSIOLOGY

Complete set of glycosyltransferase structures in the calicheamicin biosynthetic pathway reveals the origin of regiospecificity

(2011) A. Chang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Is overexpression of HER-2 a predictor of prognosis in colorectal cancer?

(2009) Dara O Kavanagh et al.   BMC CANCER

Protective Effects of Ginsenoside Rd on PC12 Cells against Hydrogen Peroxide

(2008) Ruidong Ye et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN