Systematic optimization of the yeast cell factory for sustainable and high efficiency production of bioactive ginsenoside compound K

Promotion of compound K production in Saccharomyces cerevisiae by glycerol

(2020) Weihua Nan et al.   Microbial Cell Factories

Elucidation of the complete biosynthetic pathway of the main triterpene glycosylation products of Panax notoginseng using a synthetic biology platform

(2020) Dong Wang et al.   METABOLIC ENGINEERING

Synthesizing ginsenoside Rh2 in Saccharomyces cerevisiae cell factory at high-efficiency

(2019) Pingping Wang et al.   Cell Discovery

Production of Triterpene Ginsenoside Compound K in the Non-conventional Yeast Yarrowia lipolytica

(2019) Dashuai Li et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Single- and Multiple-Dose Trials to Determine the Pharmacokinetics, Safety, Tolerability, and Sex Effect of Oral Ginsenoside Compound K in Healthy Chinese Volunteers

(2018) Lulu Chen et al.   Frontiers in Pharmacology

Food and Sex-Related Impacts on the Pharmacokinetics of a Single-Dose of Ginsenoside Compound K in Healthy Subjects

(2017) Lulu Chen et al.   Frontiers in Pharmacology

A review of biotransformation and pharmacology of ginsenoside compound K

(2015) Xi-Ding Yang et al.   FITOTERAPIA

De novo production of resveratrol from glucose or ethanol by engineered Saccharomyces cerevisiae

(2015) Mingji Li et al.   METABOLIC ENGINEERING

Recent advances in ginseng as cancer therapeutics: a functional and mechanistic overview

(2015) Alice S. T. Wong et al.   NATURAL PRODUCT REPORTS

Complete biosynthesis of opioids in yeast

(2015) S. Galanie et al.   SCIENCE

Ginsenoside compound K suppresses the abnormal activation of T lymphocytes in mice with collagen-induced arthritis

(2014) Kang-kang Liu et al.   ACTA PHARMACOLOGICA SINICA

Production of bioactive ginsenoside compound K in metabolically engineered yeast

(2014) Xing Yan et al.   CELL RESEARCH

Ginsenoside metabolite compound K attenuates inflammatory responses of adjuvant-induced arthritis rats

(2014) Huaxun Wu et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

Ginsenoside Metabolite Compound K Alleviates Adjuvant-Induced Arthritis by Suppressing T Cell Activation

(2014) Jingyu Chen et al.   INFLAMMATION

Anti-cancer effects of ginsenoside compound k on pediatric acute myeloid leukemia cells

(2013) Yan Chen et al.   Cancer Cell International

Compound K, a final intestinal metabolite of ginsenosides, enhances insulin secretion in MIN6 pancreatic β-cells by upregulation of GLUT2

(2013) Jian Gu et al.   FITOTERAPIA

High-level semi-synthetic production of the potent antimalarial artemisinin

(2013) C. J. Paddon et al.   NATURE

Joint-protective effects of compound K, a major ginsenoside metabolite, in rheumatoid arthritis: in vitro evidence

(2013) Yong Seok Choi et al.   RHEUMATOLOGY INTERNATIONAL

Hypoglycemic effect of protopanaxadiol-type ginsenosides and compound K on Type 2 Diabetes mice induced by High-Fat Diet combining with Streptozotocin via suppression of hepatic gluconeogenesis

(2011) Wei Li et al.   FITOTERAPIA

Compound K, Intestinal Metabolite of Ginsenoside, Attenuates Hepatic Lipid Accumulation via AMPK Activation in Human Hepatoma Cells

(2009) Do Yeon Kim et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY