Production of amorphadiene in yeast, and its conversion to dihydroartemisinic acid, precursor to the antimalarial agent artemisinin

Demand for malaria drug soars

(2010) Richard Van Noorden   NATURE

You're one in a googol: optimizing genes for protein expression

(2009) M. Welch et al.   Journal of the Royal Society Interface

High-Level Production of Amorpha-4,11-Diene, a Precursor of the Antimalarial Agent Artemisinin, in Escherichia coli

(2009) Hiroko Tsuruta et al.   PLoS One

Application of Functional Genomics to Pathway Optimization for Increased Isoprenoid Production

(2008) L. Kizer et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Developing an industrial artemisinic acid fermentation process to support the cost-effective production of antimalarial artemisinin-based combination therapies

(2008) Jacob R. Lenihan et al.   BIOTECHNOLOGY PROGRESS

Induction of multiple pleiotropic drug resistance genes in yeast engineered to produce an increased level of anti-malarial drug precursor, artemisinic acid

(2008) Dae-Kyun Ro et al.   BMC BIOTECHNOLOGY

Predicting Global Fund grant disbursements for procurement of artemisinin-based combination therapies

(2008) Justin M Cohen et al.   MALARIA JOURNAL

Qinghaosu (Artemisinin): The Price of Success

(2008) N. J. White   SCIENCE