4.7 Article

Development of Millettia speciosa champ polysaccharide conjugate stabilized oil-in-water emulsion for oral delivery of ll-carotene: Protection effect and in vitro digestion fate

Journal

FOOD CHEMISTRY
Volume 397, Issue -, Pages -

Publisher

ELSEVIER SCI LTD
DOI: 10.1016/j.foodchem.2022.133764

Keywords

Millettia Speciosa champ; Polysaccharide conjugate; ll-Carotene; Chemical stability; Bioaccessibility

Funding

  1. National Natural Science Foundation of China [22078111, 21878105]

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In this study, an antioxidant emulsifier called Millettia speciosa Champ polysaccharide conjugates (MSC-PC) was used to create an oil-in-water emulsion. The study focused on the effects of MSC-PC on the stability and bioaccessibility of β-carotene. The results showed that MSC-PC stabilized emulsion had excellent resistance to variations in salt levels, thermal treatments, and pH values. The emulsion also demonstrated high inhibition capacity on lipid oxidation and better protective effect on β-carotene compared to other systems.
In this study, a natural antioxidant emulsifier, Millettia speciosa Champ polysaccharide conjugates (MSC-PC), was used for fabricating oil-in-water emulsion, and the influences of MSC-PC on ll-carotene stability and bioaccessibility were studied. Results suggested that MSC-PC stabilized emulsion exhibited excellent resistance to a wide range of salt levels (0-500 mM of Na+), thermal treatments (50-90 degrees C) and pH values (3.0-11.0). MSC-PC also exhibited an outstanding inhibition capacity on lipid oxidation. Besides, MSC-PC stabilized emulsion had a better protective effect on ll-carotene than other systems. Interestingly, in spite of similar lipolysis extent, ll-carotene bioaccessibility in MSC-PC fabricated emulsion (14.75 %) was markedly higher than that in commercial Tween 80 fabricated emulsion (10.08 %), likely due to the steric-hindrance effect and antioxidant ability of MSC-PC, building interfacial layers that prevented ll-carotene from degradation. This work supplied a deep insight into elucidating the mechanisms of emulsifying performance and ll-carotene protection effect of MSC-PC fabricated emulsion.

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