HIF-1α-mediated autophagy and canonical Wnt/β-catenin signalling activation are involved in fluoride-induced osteosclerosis in rats

NaF-induced neurotoxicity via activation of the IL-1β/JNK signaling pathway

(2022) Chengzhi Zhang et al.   TOXICOLOGY

Persistent activation of Nrf2 in a p62-dependent non-canonical manner aggravates lead-induced kidney injury by promoting apoptosis and inhibiting autophagy

(2022) Cai-Yu Lian et al.   Journal of Advanced Research

New insights into crosstalk between pyroptosis and autophagy co-induced by molybdenum and cadmium in duck renal tubular epithelial cells

(2021) Caiying Zhang et al.   JOURNAL OF HAZARDOUS MATERIALS

Energy Metabolism of Osteocytes

(2021) Vivin Karthik et al.   Current Osteoporosis Reports

Arsenic-induced Autophagic Alterations and Mitochondrial Impairments in HPG-S Axis of Mature Male Mice Offspring (F1-generation): A persistent toxicity study

(2020) Mohammad Mehdi Ommati et al.   TOXICOLOGY LETTERS

Principles of fluoride toxicity and the cellular response: a review

(2020) Nichole R. Johnston et al.   ARCHIVES OF TOXICOLOGY

β-catenin mediates fluoride-induced aberrant osteoblasts activity and osteogenesis

(2020) Yanru Chu et al.   ENVIRONMENTAL POLLUTION

Increasing fluoride content deteriorates rat bone mechanical properties

(2020) Taraneh Rezaee et al.   BONE

The Role of Autophagy in Osteoclast Differentiation and Bone Resorption Function

(2020) Azadeh Montaseri et al.   Biomolecules

Role of Metabolism in Bone Development and Homeostasis

(2020) Akiko Suzuki et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The pathogenesis of endemic fluorosis: Research progress in the last 5 years

(2019) Wei Wei et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Beclin1 modulates bone homeostasis by regulating osteoclast and chondrocyte differentiation

(2019) Atsushi Arai et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Calcium Alleviates Fluoride-Induced Bone Damage by Inhibiting Endoplasmic Reticulum Stress and Mitochondrial Dysfunction

(2019) Jinming Wang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Fluoride contamination, health problems and remediation methods in Asian groundwater: A comprehensive review

(2019) Krishna Kumar Yadav et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Hydrogeochemical characterisation and health hazards of fluoride enriched groundwater in diverse aquifer types

(2019) Mobarok Hossain et al.   ENVIRONMENTAL POLLUTION

Fluoride-induced renal dysfunction via respiratory chain complex abnormal expression and fusion elevation in mice

(2019) Hong-wei Wang et al.   CHEMOSPHERE

Paternal exposure to arsenic resulted in oxidative stress, autophagy, and mitochondrial impairments in the HPG axis of pubertal male offspring

(2019) M.M. Ommati et al.   CHEMOSPHERE

Defective autophagy in osteoblasts induces endoplasmic reticulum stress and causes remarkable bone loss

(2018) Huixia Li et al.   Autophagy

Hypoxia regulates angeogenic-osteogenic coupling process via up-regulating IL-6 and IL-8 in human osteoblastic cells through hypoxia-inducible factor-1α pathway

(2018) Xiulong Niu et al.   CYTOKINE

Runx2, an inducer of osteoblast and chondrocyte differentiation

(2018) Toshihisa Komori   HISTOCHEMISTRY AND CELL BIOLOGY

Mechanism and medical implications of mammalian autophagy

(2018) Ivan Dikic et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Osteocytic oxygen sensing controls bone mass through epigenetic regulation of sclerostin

(2018) Steve Stegen et al.   Nature Communications

Fluoride induces apoptosis and autophagy through the IL-17 signaling pathway in mice hepatocytes

(2018) Yangfei Zhao et al.   ARCHIVES OF TOXICOLOGY

Clinical advantages and disadvantages of anabolic bone therapies targeting the WNT pathway

(2018) Natasha M. Appelman-Dijkstra et al.   Nature Reviews Endocrinology

Hypoxia inducible factor-1α regulates autophagy via the p27-E2F1 signaling pathway

(2017) Pan Wang et al.   Molecular Medicine Reports

Molecular mechanisms and physiological roles of Atg5/Atg7-independent alternative autophagy

(2017) Satoko ARAKAWA et al.   PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES

The role of the wnt/β-catenin signaling pathway in formation and maintenance of bone and teeth

(2016) Peipei Duan et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Gut microbiota induce IGF-1 and promote bone formation and growth

(2016) Jing Yan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Role of Collagen Organization on the Properties of Bone

(2015) Patrick Garnero   CALCIFIED TISSUE INTERNATIONAL

Hypoxia signalling manipulation for bone regeneration

(2015) Justin Drager et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

Anabolic Wnt/β-catenin signalling: osteocytes are key

(2015) Jenny Buckland   Nature Reviews Rheumatology

Evolution of Atg1 function and regulation

(2014) Edmond Y. Chan et al.   Autophagy

Autophagy in osteoblasts is involved in mineralization and bone homeostasis

(2014) Marie Nollet et al.   Autophagy

To Wnt or not to Wnt: the bone and joint health dilemma

(2013) Rik J. Lories et al.   Nature Reviews Rheumatology

Fluoride promotes osteoblastic differentiation through canonical Wnt/β-catenin signaling pathway

(2013) Leilei Pan et al.   TOXICOLOGY LETTERS

Sources and toxicity of fluoride in the environment

(2012) Aniruddha Ghosh et al.   RESEARCH ON CHEMICAL INTERMEDIATES

Role of HIF-1α in skeletal development

(2010) Chao Wan et al.   Annals of the New York Academy of Sciences

Molecular mechanisms of fluoride toxicity

(2010) Olivier Barbier et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Pathway-based genome-wide association analysis identified the importance of regulation-of-autophagy pathway for ultradistal radius BMD

(2010) Lishu Zhang et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Fluoride effects on bone crystals

(2010) Marc D. Grynpas   JOURNAL OF BONE AND MINERAL RESEARCH

Role of hypoxia-inducible factor-1α in angiogenic–osteogenic coupling

(2009) Ryan C. Riddle et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Targeted Deletion of the Sclerostin Gene in Mice Results in Increased Bone Formation and Bone Strength

(2008) Xiaodong Li et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Autophagy fights disease through cellular self-digestion

(2008) Noboru Mizushima et al.   NATURE