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Title
Runx2, an inducer of osteoblast and chondrocyte differentiation
Authors
Keywords
Ihh, Sp7, Wnt, Cbfb, Osteoarthritis, Cancer
Journal
HISTOCHEMISTRY AND CELL BIOLOGY
Volume 149, Issue 4, Pages 313-323
Publisher
Springer Nature
Online
2018-01-22
DOI
10.1007/s00418-018-1640-6
References
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Note: Only part of the references are listed.- RUNX2 expression in thyroid and breast cancer requires the cooperation of three non-redundant enhancers under the control of BRD4 and c-JUN
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- Deletion of Runx2 in Articular Chondrocytes Decelerates the Progression of DMM-Induced Osteoarthritis in Adult Mice
- (2017) Lifan Liao et al. Scientific Reports
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- (2017) Atsushi Takahashi et al. Scientific Reports
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- (2016) Xin Wang et al. CANCER RESEARCH
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- (2016) Qing Jiang et al. JOURNAL OF BONE AND MINERAL RESEARCH
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- (2016) Martha C. Castaño-Betancourt et al. PLoS Genetics
- Histone Deacetylase Inhibitors Repress Tumoral Expression of the Proinvasive Factor RUNX2
- (2015) V. Sancisi et al. CANCER RESEARCH
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- Core Binding Factor β of Osteoblasts Maintains Cortical Bone Mass via Stabilization of Runx2 in Mice
- (2015) Kyung-Eun Lim et al. JOURNAL OF BONE AND MINERAL RESEARCH
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- (2015) Xin Qin et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Conditional Deletion of Indian Hedgehog in Limb Mesenchyme Results in Complete Loss of Growth Plate Formation but Allows Mature Osteoblast Differentiation
- (2015) Katsuhiko Amano et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Loss of Osteoblast Runx3 Produces Severe Congenital Osteopenia
- (2015) Omri Bauer et al. MOLECULAR AND CELLULAR BIOLOGY
- Deletion of core-binding factor β (Cbfβ) in mesenchymal progenitor cells provides new insights into Cbfβ/Runxs complex function in cartilage and bone development
- (2014) Mengrui Wu et al. BONE
- Runx2 Is a Novel Regulator of Mammary Epithelial Cell Fate in Development and Breast Cancer
- (2014) T. W. Owens et al. CANCER RESEARCH
- Runx2 activity in committed osteoblasts is not essential for embryonic skeletogenesis
- (2014) Mitra D. Adhami et al. CONNECTIVE TISSUE RESEARCH
- RUNX2 correlates with subtype-specific breast cancer in a human tissue microarray, and ectopic expression of Runx2 perturbs differentiation in the mouse mammary gland
- (2014) L. McDonald et al. Disease Models & Mechanisms
- Chondrocyte-specific Knockout of Cbfβ Reveals the Indispensable Function of Cbfβ in Chondrocyte Maturation, Growth Plate Development and Trabecular Bone Formation in Mice
- (2014) Mengrui Wu et al. International Journal of Biological Sciences
- Dlx5 and Mef2 Regulate a Novel Runx2 Enhancer for Osteoblast-Specific Expression
- (2014) Tetsuya Kawane et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Core Binding Factor Beta (Cbfβ) Controls the Balance of Chondrocyte Proliferation and Differentiation by Upregulating Indian hedgehog (Ihh) Expression and Inhibiting Parathyroid Hormone-Related Protein Receptor (PPR) Expression in Postnatal Cartilage and
- (2014) Fei Tian et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Runx2 Regulates Endochondral Ossification Through Control of Chondrocyte Proliferation and Differentiation
- (2014) Haiyan Chen et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Runx2-I Isoform Contributes to Fetal Bone Formation Even in the Absence of Specific N-Terminal Amino Acids
- (2014) Hideaki Okura et al. PLoS One
- Cbf deletion in mice recapitulates cleidocranial dysplasia and reveals multiple functions of Cbf required for skeletal development
- (2014) W. Chen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Decreased histone deacetylase 4 is associated with human osteoarthritis cartilage degeneration by releasing histone deacetylase 4 inhibition of runt-related transcription factor-2 and increasing osteoarthritis-related genes: a novel mechanism of human osteoarthritis cartilage degeneration
- (2014) Kun Cao et al. ARTHRITIS RESEARCH & THERAPY
- An analysis of skeletal development in osteoblast-specific and chondrocyte-specific runt-related transcription factor-2 (Runx2) knockout mice
- (2013) Takeshi Takarada et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Clinical significance of RUNX2 expression in patients with nonsmall cell lung cancer: a 5-year follow-up study
- (2013) Hong Li et al. TUMOR BIOLOGY
- Runt-related transcription factor 2 in human colon carcinoma: A potent prognostic factor associated with estrogen receptor
- (2012) Tomohiko Sase et al. INTERNATIONAL JOURNAL OF CANCER
- Osterix Regulates Calcification and Degradation of Chondrogenic Matrices through Matrix Metalloproteinase 13 (MMP13) Expression in Association with Transcription Factor Runx2 during Endochondral Ossification
- (2012) Riko Nishimura et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The cancer-related transcription factor Runx2 modulates cell proliferation in human osteosarcoma cell lines
- (2012) Claudia M.J. Lucero et al. JOURNAL OF CELLULAR PHYSIOLOGY
- RUNX2 in mammary gland development and breast cancer
- (2012) Nicola Ferrari et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Runx2 Isoform I Controls a Panel of Proinvasive Genes Driving Aggressiveness of Papillary Thyroid Carcinomas
- (2012) Valentina Sancisi et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study
- (2012) LANCET
- SP7 Inhibits Osteoblast Differentiation at a Late Stage in Mice
- (2012) Carolina A. Yoshida et al. PLoS One
- Osteocyte Network; a Negative Regulatory System for Bone Mass Augmented by the Induction of Rankl in Osteoblasts and Sost in Osteocytes at Unloading
- (2012) Takeshi Moriishi et al. PLoS One
- Early onset of Runx2 expression caused craniosynostosis, ectopic bone formation, and limb defects
- (2011) Takafumi Maeno et al. BONE
- Indian hedgehog positively regulates calvarial ossification and modulates bone morphogenetic protein signaling
- (2011) Kelly Lenton et al. GENESIS
- C/EBPβ and RUNX2 cooperate to degrade cartilage with MMP-13 as the target and HIF-2α as the inducer in chondrocytes
- (2011) Makoto Hirata et al. HUMAN MOLECULAR GENETICS
- Runx2 contributes to murine Col10a1 gene regulation through direct interaction with its cis-enhancer
- (2011) Feifei Li et al. JOURNAL OF BONE AND MINERAL RESEARCH
- TNF-α's effects on proliferation and apoptosis in human mesenchymal stem cells depend on RUNX2 expression
- (2010) Olfa Ghali et al. JOURNAL OF BONE AND MINERAL RESEARCH
- The cancer-related Runx2 protein enhances cell growth and responses to androgen and TGFβ in prostate cancer cells
- (2010) Margaretha van der Deen et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Regulation of mechanical stress-induced MMP-13 and ADAMTS-5 expression by RUNX-2 transcriptional factor in SW1353 chondrocyte-like cells
- (2010) T. Tetsunaga et al. OSTEOARTHRITIS AND CARTILAGE
- Ectopic Runx2 Expression in Mammary Epithelial Cells Disrupts Formation of Normal Acini Structure: Implications for Breast Cancer Progression
- (2009) J. Pratap et al. CANCER RESEARCH
- Regulation of bone development and extracellular matrix protein genes by RUNX2
- (2009) Toshihisa Komori CELL AND TISSUE RESEARCH
- Runx2 regulates survivin expression in prostate cancer cells
- (2009) Minyoung Lim et al. LABORATORY INVESTIGATION
- Trafficking, development and hedgehog
- (2009) Fiona Simpson et al. MECHANISMS OF DEVELOPMENT
- Runx2 association with progression of prostate cancer in patients: mechanisms mediating bone osteolysis and osteoblastic metastatic lesions
- (2009) J Akech et al. ONCOGENE
- Runx2 Transcriptional Activation of Indian Hedgehog and a Downstream Bone Metastatic Pathway in Breast Cancer Cells
- (2008) J. Pratap et al. CANCER RESEARCH
- Co-stimulation of the Bone-relatedRunx2P1 Promoter in Mesenchymal Cells by SP1 and ETS Transcription Factors at Polymorphic Purine-rich DNA Sequences (Y-repeats)
- (2008) Ying Zhang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Positive Regulation of Adult Bone Formation by Osteoblast-Specific Transcription Factor Osterix
- (2008) Wook-Young Baek et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Dimorphic effects of Notch signaling in bone homeostasis
- (2008) Feyza Engin et al. NATURE MEDICINE
- Notch signaling maintains bone marrow mesenchymal progenitors by suppressing osteoblast differentiation
- (2008) Matthew J Hilton et al. NATURE MEDICINE
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