Starting a new chapter on class Ia ribonucleotide reductases

Global burden of bacterial antimicrobial resistance in 2019: a systematic analysis

(2022) Christopher JL Murray et al.   LANCET

Ribonucleotide reductase, a novel drug target for gonorrhea

(2022) Jana Narasimhan et al.   eLife

In‐Cell Characterization of the Stable Tyrosyl Radical in E. coli Ribonucleotide Reductase via Advanced EPR Spectroscopy

(2021) Shari Lorraine Meichsner et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Detection of Water Molecules on the Radical Transfer Pathway of Ribonucleotide Reductase by 17O Electron–Nuclear Double Resonance Spectroscopy

(2021) Fabian Hecker et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Glutamate Mediates Proton-Coupled Electron Transfer Between Tyrosines 730 and 731 in Escherichia coli Ribonucleotide Reductase

(2021) Clorice R. Reinhardt et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

RNR inhibitor binding studies of Chlamydia felis: insights from in silico molecular modeling, docking, and simulation studies

(2021) B. S. Ravindranath et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Characterization of ribonucleotide reductases of emerging pathogens Elizabethkingia anophelis and Elizabethkingia meningoseptica and streptonigrin as their inhibitor: a computational study

(2021) A. M. U. B Mahfuz et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Detection of Catalytically Linked Conformational Changes in Wild-Type Class Ia Ribonucleotide Reductase Using Reaction-Induced FTIR Spectroscopy

(2021) Ryan Atlee Watson et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Structural and Biochemical Investigation of Class I Ribonucleotide Reductase from the Hyperthermophile Aquifex aeolicus

(2021) Daniel Rehling et al.   BIOCHEMISTRY

The periodic table of ribonucleotide reductases

(2021) Terry B. Ruskoski et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural and functional insight into thiazolidinone derivatives as novel candidates for anticancer drug design: in vitro biological and in-silico strategies

(2021) Pervaiz Ali Channar et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Effects of chameleon dispense-to-plunge speed on particle concentration, complex formation, and final resolution: A case study using the Neisseria gonorrhoeae ribonucleotide reductase inactive complex

(2021) Talya S. Levitz et al.   JOURNAL OF STRUCTURAL BIOLOGY

Structure of a trapped radical transfer pathway within a ribonucleotide reductase holocomplex

(2020) Gyunghoon Kang et al.   SCIENCE

Ribonucleotide Reductases: Structure, Chemistry, and Metabolism Suggest New Therapeutic Targets

(2020) Brandon L. Greene et al.   Annual Review of Biochemistry

Conformational Motions and Water Networks at the α/β Interface in E. coli Ribonucleotide Reductase

(2020) Clorice R. Reinhardt et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Identification of interaction domains in the pseudorabies virus ribonucleotide reductase large and small subunits

(2020) Chuang Lyu et al.   VETERINARY MICROBIOLOGY

UCSF ChimeraX : Structure visualization for researchers, educators, and developers

(2020) Eric F. Pettersen et al.   PROTEIN SCIENCE

Elucidating the Inhibitory Effect of Resveratrol and Its Structural Analogs on Selected Nucleotide-Related Enzymes

(2020) Yifei Wu et al.   Biomolecules

Gated Proton Release during Radical Transfer at the Subunit Interface of Ribonucleotide Reductase

(2020) Chang Cui et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

3.3-Å resolution cryo-EM structure of human ribonucleotide reductase with substrate and allosteric regulators bound

(2018) Edward J Brignole et al.   eLife

Single-particle cryo-EM—How did it get here and where will it go

(2018) Yifan Cheng   SCIENCE

Long-range proton-coupled electron transfer in the Escherichia coli class Ia ribonucleotide reductase

(2017) Steven Y. Reece et al.   Essays in Biochemistry

Glutamate 52-β at the α/β subunit interface ofEscherichia coliclass Ia ribonucleotide reductase is essential for conformational gating of radical transfer

(2017) Qinghui Lin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Allosteric Inhibition of Human Ribonucleotide Reductase by dATP Entails the Stabilization of a Hexamer

(2016) Nozomi Ando et al.   BIOCHEMISTRY

Biophysical Characterization of Fluorotyrosine Probes Site-Specifically Incorporated into Enzymes: E. coli Ribonucleotide Reductase As an Example

(2016) Paul H. Oyala et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The development of cryo-EM into a mainstream structural biology technique

(2016) Eva Nogales   NATURE METHODS

Radical transfer in E. coli ribonucleotide reductase: a NH2Y731/R411A-α mutant unmasks a new conformation of the pathway residue 731

(2016) Müge Kasanmascheff et al.   Chemical Science

Molecular basis for allosteric specificity regulation in class Ia ribonucleotide reductase from Escherichia coli

(2016) Christina M Zimanyi et al.   eLife

Diversity in Overall Activity Regulation of Ribonucleotide Reductase

(2015) Venkateswara Rao Jonna et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A tyrosine–tryptophan dyad and radical-based charge transfer in a ribonucleotide reductase-inspired maquette

(2015) Cynthia V. Pagba et al.   Nature Communications

Ribonucleotide reductases: essential enzymes for bacterial life

(2014) Eduard Torrents   Frontiers in Cellular and Infection Microbiology

Reversible, Long-Range Radical Transfer in E. coli Class Ia Ribonucleotide Reductase

(2013) Ellen C. Minnihan et al.   ACCOUNTS OF CHEMICAL RESEARCH

Targeting ribonucleotide reductase for cancer therapy

(2013) Jimin Shao et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Generation of a stable, aminotyrosyl radical-induced  2 2 complex of Escherichia coli class Ia ribonucleotide reductase

(2013) E. C. Minnihan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tangled Up in Knots: Structures of Inactivated Forms of E. coli Class Ia Ribonucleotide Reductase

(2012) Christina M. Zimanyi et al.   STRUCTURE

Structural basis for allosteric regulation of human ribonucleotide reductase by nucleotide-induced oligomerization

(2011) James Wesley Fairman et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structural interconversions modulate activity of Escherichia coli ribonucleotide reductase

(2011) N. Ando et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Proton-Coupled Electron Transfer in Biology: Results from Synergistic Studies in Natural and Model Systems

(2009) Steven Y. Reece et al.   Annual Review of Biochemistry

RNRdb, a curated database of the universal enzyme family ribonucleotide reductase, reveals a high level of misannotation in sequences deposited to Genbank

(2009) Daniel Lundin et al.   BMC GENOMICS

Oligomerization Status Directs Overall Activity Regulation of theEscherichia coliClass Ia Ribonucleotide Reductase

(2008) Reza Rofougaran et al.   JOURNAL OF BIOLOGICAL CHEMISTRY