Ribonucleotide reductases: essential enzymes for bacterial life

Trace element content of sedimentary pyrite as a new proxy for deep-time ocean–atmosphere evolution

(2014) Ross R. Large et al.   EARTH AND PLANETARY SCIENCE LETTERS

Ribonucleotide reductase inhibitors hydroxyurea, didox, and trimidox inhibit human cytomegalovirus replication in vitro and synergize with ganciclovir

(2013) Sukhada Bhave et al.   ANTIVIRAL RESEARCH

A Small-Molecule Blocking Ribonucleotide Reductase Holoenzyme Formation Inhibits Cancer Cell Growth and Overcomes Drug Resistance

(2013) B. Zhou et al.   CANCER RESEARCH

Radical Scavengers as Ribonucleotide Reductase Inhibitors

(2013) Arijit Basu et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

H-NS Is a Novel Transcriptional Modulator of the Ribonucleotide Reductase Genes in Escherichia coli

(2013) M. d. M. Cendra et al.   JOURNAL OF BACTERIOLOGY

Cooperative and allosterically controlled nucleotide binding regulates the DNA binding activity of NrdR

(2013) Brandon L. McKethan et al.   MOLECULAR MICROBIOLOGY

Synthesis and Biological Evaluation of Apigenin Derivatives as Antibacterial and Antiproliferative Agents

(2013) Rui Liu et al.   MOLECULES

Ribonucleotide reductase class I with different radical generating clusters

(2012) Ane B. Tomter et al.   COORDINATION CHEMISTRY REVIEWS

Evidence That the β Subunit of Chlamydia trachomatis Ribonucleotide Reductase Is Active with the Manganese Ion of Its Manganese(IV)/Iron(III) Cofactor in Site 1

(2012) Laura M. K. Dassama et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Metallation and mismetallation of iron and manganese proteins in vitro and in vivo: the class I ribonucleotide reductases as a case study

(2012) Joseph A. Cotruvo et al.   Metallomics

Biofilm Modifies Expression of Ribonucleotide Reductase Genes in Escherichia coli

(2012) Maria del Mar Cendra et al.   PLoS One

Class I Ribonucleotide Reductases: Metallocofactor Assembly and Repair In Vitro and In Vivo

(2011) Joseph A. Cotruvo et al.   Annual Review of Biochemistry

DNA building blocks: keeping control of manufacture

(2011) Anders Hofer et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Shift in Ribonucleotide Reductase Gene Expression in Pseudomonas aeruginosa during Infection

(2011) Britt-Marie Sjöberg et al.   INFECTION AND IMMUNITY

CT406 Encodes a Chlamydial Ortholog of NrdR, a Repressor of Ribonucleotide Reductase

(2011) E. D. R. Case et al.   JOURNAL OF BACTERIOLOGY

NrdH-Redoxin Protein Mediates High Enzyme Activity in Manganese-reconstituted Ribonucleotide Reductase fromBacillus anthracis

(2011) Mikael Crona et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The alternative aerobic ribonucleotide reductase of Escherichia coli, NrdEF, is a manganese-dependent enzyme that enables cell replication during periods of iron starvation

(2011) Julia E. Martin et al.   MOLECULAR MICROBIOLOGY

Structural interconversions modulate activity of Escherichia coli ribonucleotide reductase

(2011) N. Ando et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Basis for Adenosylcobalamin Activation in AdoCbl-Dependent Ribonucleotide Reductases

(2010) Karl-Magnus Larsson et al.   ACS Chemical Biology

An Active Dimanganese(III)−Tyrosyl Radical Cofactor inEscherichia coliClass Ib Ribonucleotide Reductase

(2010) Joseph A. Cotruvo et al.   BIOCHEMISTRY

Ribonucleotide reduction - horizontal transfer of a required function spans all three domains

(2010) Daniel Lundin et al.   BMC EVOLUTIONARY BIOLOGY

Ribonucleotide Reductases of Salmonella Typhimurium: Transcriptional Regulation and Differential Role in Pathogenesis

(2010) Anaïs Panosa et al.   PLoS One

RNRdb, a curated database of the universal enzyme family ribonucleotide reductase, reveals a high level of misannotation in sequences deposited to Genbank

(2009) Daniel Lundin et al.   BMC GENOMICS

The Radical SAM Superfamily

(2008) Perry A. Frey et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Functional Analysis of the Streptomyces coelicolor NrdR ATP-Cone Domain: Role in Nucleotide Binding, Oligomerization, and DNA Interactions

(2008) I. Grinberg et al.   JOURNAL OF BACTERIOLOGY

Function and Regulation of Class I Ribonucleotide Reductase-Encoding Genes in Mycobacteria

(2008) Mohube B. Mowa et al.   JOURNAL OF BACTERIOLOGY

NrdI Essentiality for Class Ib Ribonucleotide Reduction in Streptococcus pyogenes

(2008) I. Roca et al.   JOURNAL OF BACTERIOLOGY

NrdI, a flavodoxin involved in maintenance of the diferric-tyrosyl radical cofactor in Escherichia coli class Ib ribonucleotide reductase

(2008) J. A. Cotruvo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA