CD27-Expressing Xenoantigen-Expanded Human Regulatory T Cells Are Efficient in Suppressing Xenogeneic Immune Response

Xenotransplantation: Current Status in Preclinical Research

(2020) Tianyu Lu et al.   Frontiers in Immunology

A novel humanized mouse model to study the function of human cutaneous memory T cells in vivo in human skin

(2020) Maria M. Klicznik et al.   Scientific Reports

CD70 expression determines the therapeutic efficacy of expanded human regulatory T cells

(2020) Rebeca Arroyo Hornero et al.   Communications Biology

Helios+ and Helios− Treg subpopulations are phenotypically and functionally distinct and express dissimilar TCR repertoires

(2019) Angela M. Thornton et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Peri‐graft porcine‐specific CD4 + FoxP3 + regulatory T cells by CD40‐CD154 blockade prevented the rejection of porcine islet graft in diabetic mice

(2019) Il‐Hee Yoon et al.   XENOTRANSPLANTATION

Foxp3 Instability Helps tTregs Distinguish Self and Non-self

(2019) Zhongmei Zhang et al.   Frontiers in Immunology

Ex Vivo Expanded Human Non-Cytotoxic CD8+CD45RClow/− Tregs Efficiently Delay Skin Graft Rejection and GVHD in Humanized Mice

(2018) Séverine Bézie et al.   Frontiers in Immunology

A Rapamycin-Based GMP-Compatible Process for the Isolation and Expansion of Regulatory T Cells for Clinical Trials

(2018) Henrieta Fraser et al.   Molecular Therapy-Methods & Clinical Development

In Vivo Costimulation Blockade-Induced Regulatory T Cells Demonstrate Dominant and Specific Tolerance to Porcine Islet Xenografts

(2017) Jingjing Wu et al.   TRANSPLANTATION

CD45RA Distinguishes CD4+CD25+CD127−/low TSDR Demethylated Regulatory T Cell Subpopulations With Differential Stability and Susceptibility to Tacrolimus-Mediated Inhibition of Suppression

(2017) Rebeca Arroyo Hornero et al.   TRANSPLANTATION

CD4+CD25Hi FoxP3+ regulatory T cells in long-term cardiac xenotransplantation

(2017) Avneesh K. Singh et al.   XENOTRANSPLANTATION

Ex vivo-expanded baboon CD39 +  regulatory T cells prevent rejection of porcine islet xenografts in NOD-SCID IL-2rγ−/− mice reconstituted with baboon peripheral blood mononuclear cells

(2017) Dandan Huang et al.   XENOTRANSPLANTATION

Interplay of Regulatory T Cell and Th17 Cells during Infectious Diseases in Humans and Animals

(2017) Sharvan Sehrawat et al.   Frontiers in Immunology

Transplantation Tolerance through Hematopoietic Chimerism: Progress and Challenges for Clinical Translation

(2017) Benedikt Mahr et al.   Frontiers in Immunology

Engineered Tolerance: Tailoring Development, Function, and Antigen-Specificity of Regulatory T Cells

(2017) Nicholas A. J. Dawson et al.   Frontiers in Immunology

Alloreactive regulatory T cells generated with retinoic acid prevent skin allograft rejection

(2014) Carolina Moore et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The importance of regulatory T-cell heterogeneity in maintaining self-tolerance

(2014) Xiaomei Yuan et al.   IMMUNOLOGICAL REVIEWS

Memory regulatory T cells reside in human skin

(2014) Robert Sanchez Rodriguez et al.   JOURNAL OF CLINICAL INVESTIGATION

CD28 Costimulation Is Essential for Human T Regulatory Expansion and Function

(2014) T. N. Golovina et al.   JOURNAL OF IMMUNOLOGY

CD27 Instructs CD4+ T Cells to Provide Help for the Memory CD8+ T Cell Response after Protein Immunization

(2014) Y. Xiao et al.   JOURNAL OF IMMUNOLOGY

Late Signals from CD27 Prevent Fas-Dependent Apoptosis of Primary CD8+ T Cells

(2014) D. V. Dolfi et al.   JOURNAL OF IMMUNOLOGY

The who's who of T-cell differentiation: Human memory T-cell subsets

(2013) Yolanda D. Mahnke et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Enhanced Suppression of the Xenogeneic T-Cell Response In Vitro by Xenoantigen Stimulated and Expanded Regulatory T Cells

(2013) Xi Jin et al.   TRANSPLANTATION

CD27 Signaling Increases the Frequency of Regulatory T Cells and Promotes Tumor Growth

(2012) C. Claus et al.   CANCER RESEARCH

Adoptive Transfer With In Vitro Expanded Human Regulatory T Cells Protects Against Porcine Islet Xenograft Rejection via Interleukin-10 in Humanized Mice

(2012) Shounan Yi et al.   DIABETES

The Role of IL-15 in Activating STAT5 and Fine-Tuning IL-17A Production in CD4 T Lymphocytes

(2012) Pushpa Pandiyan et al.   JOURNAL OF IMMUNOLOGY

Molecular Mechanisms of Treg-Mediated T Cell Suppression

(2012) Angelika Schmidt et al.   Frontiers in Immunology

Tregs prevent GVHD and promote immune reconstitution in HLA-haploidentical transplantation

(2011) M. Di Ianni et al.   BLOOD

CD44 expression positively correlates with Foxp3 expression and suppressive function of CD4+ Treg cells

(2009) Tie Liu et al.   Biology Direct

Suppressive Efficacy and Proliferative Capacity of Human Regulatory T Cells in Allogeneic and Xenogeneic Responses

(2008) Yih-Jyh Lin et al.   TRANSPLANTATION