Ex vivo-expanded baboon CD39 +  regulatory T cells prevent rejection of porcine islet xenografts in NOD-SCID IL-2rγ−/− mice reconstituted with baboon peripheral blood mononuclear cells

Integrin αvβ8-Mediated TGF-β Activation by Effector Regulatory T Cells Is Essential for Suppression of T-Cell-Mediated Inflammation

(2015) John J. Worthington et al.   IMMUNITY

The expression of CD39 on regulatory T cells is genetically driven and further upregulated at sites of inflammation

(2015) Anne Rissiek et al.   JOURNAL OF AUTOIMMUNITY

Central Role of CD45RA- Foxp3hi Memory Regulatory T Cells in Clinical Kidney Transplantation Tolerance

(2015) F. Braza et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Pig-to-Monkey Islet Xenotransplantation Using Multi-Transgenic Pigs

(2014) R. Bottino et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Functional dynamics of Foxp3+regulatory T cells in mice and humans

(2014) Khalid Bin Dhuban et al.   IMMUNOLOGICAL REVIEWS

Ex Vivo Expanded Human Regulatory T Cells Can Prolong Survival of a Human Islet Allograft in a Humanized Mouse Model

(2013) Douglas C. Wu et al.   TRANSPLANTATION

Adoptive Transfer With In Vitro Expanded Human Regulatory T Cells Protects Against Porcine Islet Xenograft Rejection via Interleukin-10 in Humanized Mice

(2012) Shounan Yi et al.   DIABETES

Ex-vivo expanded baboon CD4+ CD25Hi Treg cells suppress baboon anti-pig T and B cell immune response

(2012) Avneesh K. Singh et al.   XENOTRANSPLANTATION

Islet Xenotransplantation Using Gal-Deficient Neonatal Donors Improves Engraftment and Function

(2011) P. Thompson et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Immunologic unresponsiveness to alloantigen in vivo: a role for regulatory T cells

(2011) Kathryn J. Wood et al.   IMMUNOLOGICAL REVIEWS

Transgenic Overexpression of CD39 Protects Against Renal Ischemia-Reperfusion and Transplant Vascular Injury

(2010) S. Crikis et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Expression of CD39 by Human Peripheral Blood CD4+CD25+ T Cells Denotes a Regulatory Memory Phenotype

(2010) K. M. Dwyer et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Selective rejection of porcine islet xenografts by macrophages

(2010) Yiling Fu et al.   XENOTRANSPLANTATION

Regulatory T cells in transplantation: does extracellular adenosine triphosphate metabolism through CD39 play a crucial role?

(2010) Francisco Salcido-Ochoa et al.   Transplantation Reviews

Long-Term Controlled Normoglycemia in Diabetic Non-Human Primates After Transplantation with hCD46 Transgenic Porcine Islets

(2009) D. J. van der Windt et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Regulatory T cells enter the pancreas during suppression of type 1 diabetes and inhibit effector T cells and macrophages in a TGF-β-dependent manner

(2009) Daniel R. Tonkin et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Human Follicular Lymphoma CD39+-Infiltrating T Cells Contribute to Adenosine-Mediated T Cell Hyporesponsiveness

(2009) S. P. Hilchey et al.   JOURNAL OF IMMUNOLOGY

CD39+Foxp3+ Regulatory T Cells Suppress Pathogenic Th17 Cells and Are Impaired in Multiple Sclerosis

(2009) J. M. Fletcher et al.   JOURNAL OF IMMUNOLOGY

CD4+FoxP3+regulatory T cells confer infectious tolerance in a TGF-β–dependent manner

(2008) John Andersson et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A new Hu-PBL model for the study of human islet alloreactivity based on NOD-scid mice bearing a targeted mutation in the IL-2 receptor gamma chain gene

(2007) Marie King et al.   CLINICAL IMMUNOLOGY