IFT-A structure reveals carriages for membrane protein transport into cilia
Published 2022 View Full Article
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Title
IFT-A structure reveals carriages for membrane protein transport into cilia
Authors
Keywords
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Journal
CELL
Volume 185, Issue 26, Pages 4971-4985.e16
Publisher
Elsevier BV
Online
2022-12-02
DOI
10.1016/j.cell.2022.11.010
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Note: Only part of the references are listed.- Phylogenetic profiling and cellular analyses of ARL16 reveal roles in traffic of IFT140 and INPP5E
- (2022) Skylar I. Dewees et al. MOLECULAR BIOLOGY OF THE CELL
- ColabFold: making protein folding accessible to all
- (2022) Milot Mirdita et al. NATURE METHODS
- Structure of the ciliogenesis-associated CPLANE complex
- (2022) Gerasimos Langousis et al. Science Advances
- Conversion of anterograde into retrograde trains is an intrinsic property of intraflagellar transport
- (2022) Adrian Pascal Nievergelt et al. CURRENT BIOLOGY
- Structure of the nutrient-sensing hub GATOR2
- (2022) Max L. Valenstein et al. NATURE
- Solving the nuclear pore puzzle
- (2022) Thomas U. Schwartz SCIENCE
- In situ architecture of the ciliary base reveals the stepwise assembly of intraflagellar transport trains
- (2022) Hugo van den Hoek et al. SCIENCE
- HTR6 and SSTR3 targeting to primary cilia
- (2021) Pablo Barbeito et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Molecular basis of ciliary defects caused by compound heterozygous IFT144/WDR19 mutations found in cranioectodermal dysplasia
- (2021) Yamato Ishida et al. HUMAN MOLECULAR GENETICS
- Adaptive Cartesian and torsional restraints for interactive model rebuilding
- (2021) Tristan Ian Croll et al. Acta Crystallographica Section D-Structural Biology
- The structural basis of intraflagellar transport at a glance
- (2021) Mareike A. Jordan et al. JOURNAL OF CELL SCIENCE
- In vivo imaging shows continued association of several IFT-A, IFT-B and dynein complexes while IFT trains U-turn at the tip
- (2021) Jenna L. Wingfield et al. JOURNAL OF CELL SCIENCE
- Highly accurate protein structure prediction with AlphaFold
- (2021) John Jumper et al. NATURE
- AlphaFold Protein Structure Database: massively expanding the structural coverage of protein-sequence space with high-accuracy models
- (2021) Mihaly Varadi et al. NUCLEIC ACIDS RESEARCH
- Direct imaging of intraflagellar-transport turnarounds reveals that motors detach, diffuse, and reattach to opposite-direction trains
- (2021) Zhiqing Zhang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A WDR35-dependent coat protein complex transports ciliary membrane cargo vesicles to cilia
- (2021) Tooba Quidwai et al. eLife
- SuperPlots: Communicating reproducibility and variability in cell biology
- (2020) Samuel J. Lord et al. JOURNAL OF CELL BIOLOGY
- Anterograde trafficking of ciliary MAP kinase-like ICK/CILK1 by the IFT machinery is required for intraciliary retrograde protein trafficking
- (2020) Kentaro Nakamura et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Intraflagellar transport trains and motors: Insights from structure
- (2020) Stephanie Webb et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- UCSF ChimeraX : Structure visualization for researchers, educators, and developers
- (2020) Eric F. Pettersen et al. PROTEIN SCIENCE
- Cooperation of the IFT-A complex with the IFT-B complex is required for ciliary retrograde protein trafficking and GPCR import
- (2020) Takuya Kobayashi et al. MOLECULAR BIOLOGY OF THE CELL
- Binding of IFT22 to the intraflagellar transport complex is essential for flagellum assembly
- (2019) Stefanie Wachter et al. EMBO JOURNAL
- Establishing and regulating the composition of cilia for signal transduction
- (2019) Maxence V. Nachury et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Ciliopathy-Associated Protein Kinase ICK Requires Its Non-Catalytic Carboxyl-Terminal Domain for Regulation of Ciliogenesis
- (2019) Yoon Seon Oh et al. Cells
- Structure of the dynein-2 complex and its assembly with intraflagellar transport trains
- (2019) Katerina Toropova et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Macromolecular structure determination using X-rays, neutrons and electrons: recent developments in Phenix
- (2019) Dorothee Liebschner et al. Acta Crystallographica Section D-Structural Biology
- The molecular machines that traffic signaling receptors into and out of cilia
- (2018) Maxence V Nachury CURRENT OPINION IN CELL BIOLOGY
- BBSome trains remove activated GPCRs from cilia by enabling passage through the transition zone
- (2018) Fan Ye et al. JOURNAL OF CELL BIOLOGY
- Characterisation of molecular motions in cryo-EM single-particle data by multi-body refinement in RELION
- (2018) Takanori Nakane et al. eLife
- Crystal structure of intraflagellar transport protein 80 reveals a homo-dimer required for ciliogenesis
- (2018) Michael Taschner et al. eLife
- ISOLDE: a physically realistic environment for model building into low-resolution electron-density maps
- (2018) Tristan Ian Croll Acta Crystallographica Section D-Structural Biology
- From the resolution revolution to evolution: structural insights into the evolutionary relationships between vesicle coats and the nuclear pore
- (2018) Martin Beck et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- TULP3 is required for localization of membrane-associated proteins ARL13B and INPP5E to primary cilia
- (2018) Sarina Han et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Intraflagellar Transport Complex A Genes Differentially Regulate Cilium Formation and Transition Zone Gating
- (2018) Noémie Scheidel et al. CURRENT BIOLOGY
- The cryo-EM structure of intraflagellar transport trains reveals how dynein is inactivated to ensure unidirectional anterograde movement in cilia
- (2018) Mareike A. Jordan et al. NATURE CELL BIOLOGY
- Ciliopathy-associated mutations of IFT122 impair ciliary protein trafficking but not ciliogenesis
- (2017) Mariko Takahara et al. HUMAN MOLECULAR GENETICS
- Tubby family proteins are adapters for ciliary trafficking of integral membrane proteins
- (2017) Hemant B. Badgandi et al. JOURNAL OF CELL BIOLOGY
- Intraflagellar transport-A complex mediates ciliary entry and retrograde trafficking of ciliary G protein–coupled receptors
- (2017) Tomoaki Hirano et al. MOLECULAR BIOLOGY OF THE CELL
- cryoSPARC: algorithms for rapid unsupervised cryo-EM structure determination
- (2017) Ali Punjani et al. NATURE METHODS
- Genes and molecular pathways underpinning ciliopathies
- (2017) Jeremy F. Reiter et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Functional exploration of the IFT-A complex in intraflagellar transport and ciliogenesis
- (2017) Bing Zhu et al. PLoS Genetics
- 9Å structure of the COPI coat reveals that the Arf1 GTPase occupies two contrasting molecular environments
- (2017) Svetlana O Dodonova et al. eLife
- Model-based local density sharpening of cryo-EM maps
- (2017) Arjen J Jakobi et al. eLife
- Dynamics of the IFT machinery at the ciliary tip
- (2017) Alexander Chien et al. eLife
- IFT trains in different stages of assembly queue at the ciliary base for consecutive release into the cilium
- (2017) Jenna L Wingfield et al. eLife
- Intraflagellar transport proteins 172, 80, 57, 54, 38, and 20 form a stable tubulin‐binding IFT‐B2 complex
- (2016) Michael Taschner et al. EMBO JOURNAL
- An inactivating mutation in intestinal cell kinase,ICK, impairs hedgehog signalling and causes short rib-polydactyly syndrome
- (2016) S. Paige Taylor et al. HUMAN MOLECULAR GENETICS
- Overall Architecture of the Intraflagellar Transport (IFT)-B Complex Containing Cluap1/IFT38 as an Essential Component of the IFT-B Peripheral Subcomplex
- (2016) Yohei Katoh et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Motile and non-motile cilia in human pathology: from function to phenotypes
- (2016) Hannah M Mitchison et al. JOURNAL OF PATHOLOGY
- The ciliopathy-associated CPLANE proteins direct basal body recruitment of intraflagellar transport machinery
- (2016) Michinori Toriyama et al. NATURE GENETICS
- Microtubule doublets are double-track railways for intraflagellar transport trains
- (2016) L. Stepanek et al. SCIENCE
- The Intraflagellar Transport Machinery
- (2016) Michael Taschner et al. Cold Spring Harbor Perspectives in Biology
- Open Sesame: How Transition Fibers and the Transition Zone Control Ciliary Composition
- (2016) Francesc R. Garcia-Gonzalo et al. Cold Spring Harbor Perspectives in Biology
- Role for the IFT-A Complex in Selective Transport to the Primary Cilium
- (2016) Wenxiang Fu et al. Cell Reports
- A novel RING finger in the C-terminal domain of the coatomer protein α-COP
- (2015) Gurmeet Kaur et al. Biology Direct
- In situ structural analysis of the human nuclear pore complex
- (2015) Alexander von Appen et al. NATURE
- A general method to improve fluorophores for live-cell and single-molecule microscopy
- (2015) Jonathan B Grimm et al. NATURE METHODS
- A structure of the COPI coat and the role of coat proteins in membrane vesicle assembly
- (2015) S. O. Dodonova et al. SCIENCE
- IFT–Cargo Interactions and Protein Transport in Cilia
- (2015) Karl F. Lechtreck TRENDS IN BIOCHEMICAL SCIENCES
- FLA8/KIF3B Phosphorylation Regulates Kinesin-II Interaction with IFT-B to Control IFT Entry and Turnaround
- (2014) Yinwen Liang et al. DEVELOPMENTAL CELL
- ICK is essential for cell type-specific ciliogenesis and the regulation of ciliary transport
- (2014) T. Chaya et al. EMBO JOURNAL
- Crystal structures of IFT70/52 and IFT52/46 provide insight into intraflagellar transport B core complex assembly
- (2014) Michael Taschner et al. JOURNAL OF CELL BIOLOGY
- Regulation of Cilium Length and Intraflagellar Transport by the RCK-Kinases ICK and MOK in Renal Epithelial Cells
- (2014) Joost R. Broekhuis et al. PLoS One
- The Ciliary G-Protein-Coupled Receptor Gpr161 Negatively Regulates the Sonic Hedgehog Pathway via cAMP Signaling
- (2013) Saikat Mukhopadhyay et al. CELL
- Rules for the recognition of dilysine retrieval motifs by coatomer
- (2013) Wenfu Ma et al. EMBO JOURNAL
- Evolution of modular intraflagellar transport from a coatomer-like progenitor
- (2013) T. J. P. van Dam et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Molecular Basis of Tubulin Transport Within the Cilium by IFT74 and IFT81
- (2013) S. Bhogaraju et al. SCIENCE
- Multiplex Genome Engineering Using CRISPR/Cas Systems
- (2013) L. Cong et al. SCIENCE
- Molecular Basis for Recognition of Dilysine Trafficking Motifs by COPI
- (2012) Lauren P. Jackson et al. DEVELOPMENTAL CELL
- The IFT-A complex regulates Shh signaling through cilia structure and membrane protein trafficking
- (2012) Karel F. Liem et al. JOURNAL OF CELL BIOLOGY
- RELION: Implementation of a Bayesian approach to cryo-EM structure determination
- (2012) Sjors H.W. Scheres JOURNAL OF STRUCTURAL BIOLOGY
- Fiji: an open-source platform for biological-image analysis
- (2012) Johannes Schindelin et al. NATURE METHODS
- Ciliopathies with Skeletal Anomalies and Renal Insufficiency due to Mutations in the IFT-A Gene WDR19
- (2011) Cecilie Bredrup et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Architecture and function of IFT complex proteins in ciliogenesis
- (2011) Michael Taschner et al. DIFFERENTIATION
- Crystal structure of the intraflagellar transport complex 25/27
- (2011) Sagar Bhogaraju et al. EMBO JOURNAL
- Subunit Interactions and Organization of theChlamydomonas reinhardtiiIntraflagellar Transport Complex A Proteins
- (2011) Robert H. Behal et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Probing the role of IFT particle complex A and B in flagellar entry and exit of IFT-dynein in Chlamydomonas
- (2011) Shana M. Williamson et al. PROTOPLASMA
- The tubby family proteins
- (2011) Saikat Mukhopadhyay et al. GENOME BIOLOGY
- Features and development ofCoot
- (2010) P. Emsley et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Trafficking to the Ciliary Membrane: How to Get Across the Periciliary Diffusion Barrier?
- (2010) Maxence V. Nachury et al. Annual Review of Cell and Developmental Biology
- Structure of Coatomer Cage Proteins and the Relationship among COPI, COPII, and Clathrin Vesicle Coats
- (2010) Changwook Lee et al. CELL
- TULP3 bridges the IFT-A complex and membrane phosphoinositides to promote trafficking of G protein-coupled receptors into primary cilia
- (2010) S. Mukhopadhyay et al. GENES & DEVELOPMENT
- Retrograde Intraflagellar Transport Mutants Identify Complex A Proteins With Multiple Genetic Interactions in Chlamydomonas reinhardtii
- (2009) C. Iomini et al. GENETICS
- Electron-tomographic analysis of intraflagellar transport particle trains in situ
- (2009) Gaia Pigino et al. JOURNAL OF CELL BIOLOGY
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